Synthesis and Biological Evaluation of Novel Thiazole Analogs with Both Anti‐Proliferative and Mechanistic Analyses and Molecular Docking Studies

New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation

(2022) Ali Oubella et al.   MOLECULES

Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis

(2021) Islam M. Abdel-Rahman et al.   BIOORGANIC CHEMISTRY

Hybrid of the 1,2,3‐triazole nucleus and sesquiterpene skeleton as a potential antitumor agent: Hemisynthesis, Molecular structure, Hirshfeld surface analysis, DFT , in vitro cytotoxic and apoptotic effects

(2021) Abdoullah Bimoussa et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Thiazolidinone-linked1,2,3-triazoles with monoterpenic skeleton as new potential anticancer agents: Design, synthesis and molecular docking studies

(2021) Ali Oubella et al.   BIOORGANIC CHEMISTRY

Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol

(2021) Yassine Laamari et al.   BIOORGANIC CHEMISTRY

Himachalol induces apoptosis in B16-F10 murine melanoma cells and protects against skin carcinogenesis

(2020) Wassim Shebaby et al.   JOURNAL OF ETHNOPHARMACOLOGY

Synthesis, cytotoxicity, and in vivo antitumor activity study of parthenolide semicarbazones and thiosemicarbazones

(2020) Xinxin Jia et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies

(2020) Eman A. Fayed et al.   BIOORGANIC CHEMISTRY

Synthesis and Antitumor Activity of Novel Heterocyclic Systems with Monoterpenic Skeleton Combining Dichlorocyclopropane and 1,3,4‐Thiadiazole Nucleus

(2020) Ali Oubella et al.   ChemistrySelect

Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1,2,4-oxadiazole hybrids as potential anticancer agents

(2020) Az-Eddine El Mansouri et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Efficient one-pot, three-component procedure to prepare new α-aminophosphonate and phosphonic acid acyclic nucleosides

(2020) Laila Baddi et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Design, synthesis and biological evaluation of some pyrazole derivatives containing (thio)semicarbazide as anti-inflammatory-antimicrobial agents

(2019) Zhaochang Liang et al.   Letters in Drug Design & Discovery

How to utilize academic research efforts in cancer drug discovery

(2019) Gervais Bérubé   Expert Opinion on Drug Discovery

Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis

(2019) Tahia K. Mohamed et al.   BIOORGANIC CHEMISTRY

Cell death: a review of the major forms of apoptosis, necrosis and autophagy

(2019) Mark S D’Arcy   CELL BIOLOGY INTERNATIONAL

Hemisynthesis, crystal structure and inhibitory effect of sesquiterpenic thiosemicarbazones and thiazolidin-4-ones on the corrosion behaviour of stainless steel in 1 M H2SO4 solution

(2019) Abdoullah Bimoussa et al.   Acta Crystallographica Section C-Structural Chemistry

Diastereoselective synthesis and cytotoxic evaluation of new isoxazoles and pyrazoles with monoterpenic skeleton

(2019) Ali Oubella et al.   JOURNAL OF MOLECULAR STRUCTURE

The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis

(2018) Hamid E. Daaboul et al.   BIOMEDICINE & PHARMACOTHERAPY

Synthesis of novel ring-contracted artemisinin dimers with potent anticancer activities

(2018) Ning Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and anticancer activity of new dihydropyrimidinone derivatives

(2018) Amany S. Mostafa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis pathway

(2018) Yunyun Wang et al.   BIOORGANIC CHEMISTRY

β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo

(2017) Hamid E. Daaboul et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot

(2016) Robin I. Taleb et al.   JOURNAL OF ETHNOPHARMACOLOGY

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation

(2014) Marcos Veríssimo de Oliveira Cardoso et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vitro antiparasitic activity of new thiosemicarbazones in strains of Trypanosoma cruzi

(2014) Adriana Moreno-Rodríguez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antioxidant activities of the nickel(II), iron(III) and oxovanadium(IV) complexes with N2O2 chelating thiosemicarbazones

(2014) Tülay Bal-Demirci et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Antiviral activity against the hepatitis C virus (HCV) of 1-indanone thiosemicarbazones and their inclusion complexes with hydroxypropyl-β-cyclodextrin

(2012) Romina J. Glisoni et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis, characterization and cytotoxicity of palladium(II) complex of 3-[(2-hydroxy-benzylidene)-amino]-2-thioxo-imidazolidin-4-one

(2012) Biljana Smit et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Isatin 1,2,3-triazoles as potent inhibitors against caspase-3

(2011) Yang Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Gabedit-A graphical user interface for computational chemistry softwares

(2010) Abdul-Rahman Allouche   JOURNAL OF COMPUTATIONAL CHEMISTRY

Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells

(2008) Dong-Hyung Cho et al.   CANCER LETTERS

Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivatives

(2007) Renata B. de Oliveira et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY