Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition

(2021) Sravan Gopalkrishnashetty Sreenivasmurthy et al.   PHYTOMEDICINE

Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease

(2021) Ashok Iyaswamy et al.   PHYTOMEDICINE

A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Ab oligomers from Alzheimer brain

(2020) Shaomin Li et al.   JOURNAL OF NEUROCHEMISTRY

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study

(2020) Rola Ismail et al.   Journal of Neuroinflammation

Magnetic nanoemulsions as candidates for alzheimer’s disease dual imaging theranostics

(2020) Orestis Antonoglou et al.   NANOTECHNOLOGY

How Does the Mono-Triazole Derivative Modulate Aβ42 Aggregation and Disrupt a Protofibril Structure: Insights from Molecular Dynamics Simulations

(2020) Amandeep Kaur et al.   ACS Omega

Aβ oligomers trigger and accelerate Aβ seeding

(2019) Natalie Katzmarski et al.   BRAIN PATHOLOGY

NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models

(2019) Ashok Iyaswamy et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

(2019) Ju‐Xian Song et al.   AGING CELL

Phosphorylation Signaling in APP Processing in Alzheimer’s Disease

(2019) Tao Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aging and Alzheimer's disease pathology

(2019) Renpei Sengoku   NEUROPATHOLOGY

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

(2018) Rosa Puertollano et al.   EMBO JOURNAL

Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer’s disease

(2018) Boaz Styr et al.   NATURE NEUROSCIENCE

Temporal and regional progression of Alzheimer’s disease-like pathology in 3xTg-AD mice

(2018) Ramona Belfiore et al.   AGING CELL

Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity

(2017) Yinhui Li et al.   Chemical Science

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

(2016) Yinhui Li et al.   BIOMATERIALS

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

From Companion Diagnostics to Theranostics: A New Avenue for Alzheimer’s Disease?

(2016) Maria Laura Bolognesi et al.   JOURNAL OF MEDICINAL CHEMISTRY

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing A  Generation and Amyloid Plaque Pathogenesis

(2015) Q. Xiao et al.   JOURNAL OF NEUROSCIENCE

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

(2014) Michela Guglielmotto et al.   Autophagy

Past and Recent Progress of Molecular Imaging Probes for β-Amyloid Plaques in the Brain

(2013) Mengchao Cui   CURRENT MEDICINAL CHEMISTRY

Conformational Differences between Two Amyloid β Oligomers of Similar Size and Dissimilar Toxicity

(2012) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural features and cytotoxicity of amyloid oligomers: Implications in Alzheimer's disease and other diseases with amyloid deposits

(2012) Massimo Stefani   PROGRESS IN NEUROBIOLOGY

Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau

(2012) Yang Hong-Qi et al.   Translational Neurodegeneration

Inhibition of Beta-Amyloid Peptide Aggregation by Multifunctional Carbazole-Based Fluorophores

(2011) Wanggui Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Autophagy failure in Alzheimer's disease—locating the primary defect

(2011) Ralph A. Nixon et al.   NEUROBIOLOGY OF DISEASE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE