Toll-like receptor agonist combinations augment mouse T-cell anti-tumor immunity via IL-12- and interferon ß-mediated suppression of immune checkpoint receptor expression

B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity

(2022) Aubrey S Smith et al.   Journal for ImmunoTherapy of Cancer

Memory IgM protects endogenous insulin from autoimmune destruction

(2021) Timm Amendt et al.   EMBO JOURNAL

Identification of Immune Cell Infiltration in Murine Pheochromocytoma during Combined Mannan-BAM, TLR Ligand, and Anti-CD40 Antibody-Based Immunotherapy

(2021) Ondrej Uher et al.   Cancers

COVID-19 vaccine side effects: The positives about feeling bad

(2021) Jonathan Sprent et al.   Science Immunology

COVID-19 Vaccine Frontrunners and Their Nanotechnology Design

(2020) Young Hun Chung et al.   ACS Nano

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

(2020) Rinke Bos et al.   npj Vaccines

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

(2019) Nicolas Jacquelot et al.   CELL RESEARCH

TLR2 Stimulation Increases Cellular Metabolism in CD8+ T Cells and Thereby Enhances CD8+ T Cell Activation, Function, and Antiviral Activity

(2019) Ejuan Zhang et al.   JOURNAL OF IMMUNOLOGY

TIGIT as an emerging immune checkpoint

(2019) H. Harjunpää et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Anti-CTLA-4 antibodies in cancer immunotherapy: selective depletion of intratumoral regulatory T cells or checkpoint blockade?

(2018) Fei Tang et al.   Cell and Bioscience

TLR Stimulation During T-cell Activation Lowers PD-1 Expression on CD8+ T Cells

(2018) Christopher D. Zahm et al.   Cancer Immunology Research

Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis

(2018) Andrea C Tricco et al.   BMJ-British Medical Journal

The Emerging Role of CD244 Signaling in Immune Cells of the Tumor Microenvironment

(2018) Laura Agresta et al.   Frontiers in Immunology

Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8 + T Cells

(2017) Christopher D. Zahm et al.   Cancer Immunology Research

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

(2016) Henrique Lemos et al.   CANCER RESEARCH

In situvaccination for the treatment of cancer

(2016) Linda Hammerich et al.   Immunotherapy

The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer

(2016) Heikki Huhta et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Species-specific TLR signalling — insight into human disease

(2016) Darren J. Perkins et al.   Nature Reviews Rheumatology

The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlates with Disease Progression in HIV-Infected Subjects

(2015) Xiaoling Tian et al.   JOURNAL OF IMMUNOLOGY

The Combination of ISCOMATRIX Adjuvant and TLR Agonists Induces Regression of Established Solid Tumors In Vivo

(2015) Anabel Silva et al.   JOURNAL OF IMMUNOLOGY

PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization

(2015) B. T. Rekoske et al.   Cancer Immunology Research

PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo

(2015) R. Takemura et al.   Cancer Immunology Research

Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine

(2014) Azadeh Sajadian et al.   ARCHIVES OF VIROLOGY

Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion

(2014) Robert L. Ferris et al.   JOURNAL OF IMMUNOLOGY

CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression

(2014) Selena Viganò et al.   PLoS Pathogens

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The androgen receptor: a biologically relevant vaccine target for the treatment of prostate cancer

(2012) Brian M. Olson et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Enterovirus 71 blocks selectively type I interferon production through the 3C viral protein in mice

(2012) Yi-Ping Lee et al.   JOURNAL OF MEDICAL VIROLOGY

Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice

(2012) S Domingos-Pereira et al.   Mucosal Immunology

Mice, men and the relatives: cross-species studies underpin innate immunity

(2012) C. E. Bryant et al.   Open Biology

Interplay between CD8α+ Dendritic Cells and Monocytes in Response to Listeria monocytogenes Infection Attenuates T Cell Responses

(2011) Dilnawaz Kapadia et al.   PLoS One

Therapeutic Targeting of TLR9 Inhibits Cell Growth and Induces Apoptosis in Neuroblastoma

(2010) C. Brignole et al.   CANCER RESEARCH

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

(2010) H.-T. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFN-  Enhances Peptide Vaccine-Induced CD8+ T Cell Numbers, Effector Function, and Antitumor Activity

(2009) A. G. Sikora et al.   JOURNAL OF IMMUNOLOGY

Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival

(2009) Q. Chen et al.   JOURNAL OF IMMUNOLOGY