Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis

Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke

(2021) Jong-Won Chung et al.   NEUROLOGY

The effects of intravenous infusion of autologous mesenchymal stromal cells in patients with subacute middle cerebral artery infarct: a phase 2 randomized controlled trial on safety, tolerability and efficacy

(2021) Zhe Kang Law et al.   CYTOTHERAPY

Combining cell therapy with human autologous Schwann cell and bone marrow-derived mesenchymal stem cell in patients with subacute complete spinal cord injury: safety considerations and possible outcomes

(2021) Saeed Oraee-Yazdani et al.   Stem Cell Research & Therapy

The Efficacy of Mesenchymal Stem Cell Therapies in Rodent Models of Multiple Sclerosis: An Updated Systematic Review and Meta-Analysis

(2021) Jialin He et al.   Frontiers in Immunology

Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial

(2021) Antonio Uccelli et al.   LANCET NEUROLOGY

Transplantation of rat cranial bone-derived mesenchymal stem cells promotes functional recovery in rats with spinal cord injury

(2021) Yuyo Maeda et al.   Scientific Reports

The safety of MSC therapy over the past 15 years: a meta-analysis

(2021) Yang Wang et al.   Stem Cell Research & Therapy

PNS154 THE PRISMA 2020 STATEMENT: DEVELOPMENT OF AND KEY CHANGES IN AN UPDATED GUIDELINE FOR REPORTING SYSTEMATIC REVIEWS AND META-ANALYSES

(2020) J. Tetzlaff et al.   VALUE IN HEALTH

Autologous Mesenchymal Stem Cells Improve Motor Recovery in Subacute Ischemic Stroke: a Randomized Clinical Trial

(2020) Assia Jaillard et al.   Translational Stroke Research

Shattering barriers toward clinically meaningful MSC therapies

(2020) Oren Levy et al.   Science Advances

Clinical effects of intrathecal administration of expanded Wharton jelly mesenchymal stromal cells in patients with chronic complete spinal cord injury: a randomized controlled study

(2020) Sergiu Albu et al.   CYTOTHERAPY

Mesenchymal Stem Cell Immunomodulation: Mechanisms and Therapeutic Potential

(2020) Na Song et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis

(2020) Panayiota Petrou et al.   BRAIN

Repeated subarachnoid administrations of allogeneic human umbilical cord mesenchymal stem cells for spinal cord injury: a phase 1/2 pilot study

(2020) Yang Yang et al.   CYTOTHERAPY

Mitochondrial Transfer and Regulators of Mesenchymal Stromal Cell Function and Therapeutic Efficacy

(2020) Amina Mohammadalipour et al.   Frontiers in Cell and Developmental Biology

Mesenchymal Stem Cell Migration and Tissue Repair

(2019) Fu et al.   Cells

Phase I/II Study of Safety and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Chronic Stroke

(2019) Michael L. Levy et al.   STROKE

Autologous Mesenchymal Stem Cell Transplantation in Multiple Sclerosis: A Meta-Analysis

(2019) Yang Zhou et al.   Stem Cells International

Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis—A Phase I Study

(2019) Ellen Iacobaeus et al.   Journal of Clinical Medicine

Cell therapy with autologous mesenchymal stromal cells in post-traumatic syringomyelia

(2018) Jesús Vaquero et al.   CYTOTHERAPY

Intrathecal administration of autologous mesenchymal stromal cells for spinal cord injury: Safety and efficacy of the 100/3 guideline

(2018) Jesús Vaquero et al.   CYTOTHERAPY

Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis

(2018) Neil H. Riordan et al.   Journal of Translational Medicine

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study

(2018) Oscar Fernández et al.   PLoS One

Tissue repair and regeneration with endogenous stem cells

(2018) Huimin Xia et al.   Nature Reviews Materials

Phase I Trial of Intrathecal Mesenchymal Stem Cell-derived Neural Progenitors in Progressive Multiple Sclerosis

(2018) Violaine K. Harris et al.   EBioMedicine

Therapeutic Use of Intrathecal Mesenchymal Stem Cells in patients with Multiple Sclerosis: A Pilot Study with Booster Injection

(2018) Mohammad Ali Sahraian et al.   IMMUNOLOGICAL INVESTIGATIONS

Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial

(2018) Cecilie Gjerde et al.   Stem Cell Research & Therapy

Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

(2017) David C Hess et al.   LANCET NEUROLOGY

Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis

(2017) Jeffrey A Cohen et al.   Multiple Sclerosis Journal

Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis

(2017) Jeffrey A Cohen et al.   Multiple Sclerosis Journal

Autologous mesenchymal stromal cell transplantation for spinal cord injury: A Phase I pilot study

(2016) Humayoon Shafique Satti et al.   CYTOTHERAPY

Clinical safety of intrathecal administration of mesenchymal stromal cell–derived neural progenitors in multiple sclerosis

(2016) Violaine K. Harris et al.   CYTOTHERAPY

An approach to personalized cell therapy in chronic complete paraplegia: The Puerta de Hierro phase I/II clinical trial

(2016) Jesús Vaquero et al.   CYTOTHERAPY

A Phase III Clinical Trial Showing Limited Efficacy of Autologous Mesenchymal Stem Cell Therapy for Spinal Cord Injury

(2016) Sun Kyu Oh et al.   NEUROSURGERY

Clinical Outcomes of Transplanted Modified Bone Marrow–Derived Mesenchymal Stem Cells in Stroke

(2016) Gary K. Steinberg et al.   STROKE

Co-transplantation of autologous bone marrow mesenchymal stem cells and Schwann cells through cerebral spinal fluid for the treatment of patients with chronic spinal cord injury: safety and possible outcome

(2015) S Oraee-Yazdani et al.   SPINAL CORD

Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities

(2015) Antonio J. Salgado et al.   Frontiers in Cellular Neuroscience

Differential Migration of Mesenchymal Stem Cells to Ischemic Regions after Middle Cerebral Artery Occlusion in Rats

(2015) Soo Hyun Lee et al.   PLoS One

A Two-Year Follow-Up Study of Cotransplantation with Neural Stem/Progenitor Cells and Mesenchymal Stromal Cells in Ischemic Stroke Patients

(2014) Li-Yan Qiao et al.   CELL TRANSPLANTATION

The Potential of Human Umbilical Cord-Derived Mesenchymal Stem Cells as a Novel Cellular Therapy for Multiple Sclerosis

(2014) Jin-Feng Li et al.   CELL TRANSPLANTATION

Clinical observation of umbilical cord mesenchymal stem cell transplantation in treatment for sequelae of thoracolumbar spinal cord injury

(2014) Hongbin Cheng et al.   Journal of Translational Medicine

Randomized Placebo-Controlled Phase II Trial of Autologous Mesenchymal Stem Cells in Multiple Sclerosis

(2014) Sara Llufriu et al.   PLoS One

Safety and neurological assessments after autologous transplantation of bone marrow mesenchymal stem cells in subjects with chronic spinal cord injury

(2014) Marcus Vinícius Mendonça et al.   Stem Cell Research & Therapy

Human placenta-derived cells (PDA-001) for the treatment of adults with multiple sclerosis: A randomized, placebo-controlled, multiple-dose study

(2014) Fred D. Lublin et al.   Multiple Sclerosis and Related Disorders

Safety and possible outcome assessment of autologous Schwann cell and bone marrow mesenchymal stromal cell co-transplantation for treatment of patients with chronic spinal cord injury

(2013) Saeed Oraee Yazdani et al.   CYTOTHERAPY

Comparative analysis of curative effect of CT-guided stem cell transplantation and open surgical transplantation for sequelae of spinal cord injury

(2013) Guanghui Dai et al.   Journal of Translational Medicine

Clinical safety and primary efficacy of bone marrow mesenchymal cell transplantation in subacute spinal cord injured patients

(2012) Saeid Karamouzian et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

(2012) Peter Connick et al.   LANCET NEUROLOGY

Autologous Mesenchymal Stem Cell Therapy in Progressive Multiple Sclerosis: An Open Label Study

(2012) Mandana Mohyeddin Bonab et al.   Current Stem Cell Research & Therapy

Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion

(2012) E. Eggenhofer et al.   Frontiers in Immunology

Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke

(2011) O. Honmou et al.   BRAIN

Autologous mesenchymal stem cells in chronic spinal cord injury

(2011) Yanish Bhanot et al.   BRITISH JOURNAL OF NEUROSURGERY

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study

(2010) Bassem Yamout et al.   JOURNAL OF NEUROIMMUNOLOGY

The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study Group

(2010) Mark S Freedman et al.   Multiple Sclerosis Journal

Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study

(2009) Rakhi Pal et al.   CYTOTHERAPY