The effect of local IL-4 delivery or CCL2 blockade on implant fixation and bone structural properties in a mouse model of wear particle induced osteolysis

Local delivery of mutant CCL2 protein-reduced orthopaedic implant wear particle-induced osteolysis and inflammation in vivo

(2015) Xinyi Jiang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Modulation of mouse macrophage polarizationin vitrousing IL-4 delivery by osmotic pumps

(2014) Jukka Pajarinen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Characterization of macrophage polarizing cytokines in the aseptic loosening of total hip replacements

(2014) Eemeli Jämsen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement

(2014) S. B. Goodman et al.   Journal of the Royal Society Interface

Interaction of materials and biology in total joint replacement – successes, challenges and future directions

(2014) J. Pajarinen et al.   Journal of Materials Chemistry B

Rethinking Regenerative Medicine: A Macrophage-Centered Approach

(2014) Bryan N. Brown et al.   Frontiers in Immunology

The response of macrophages to titanium particles is determined by macrophage polarization

(2013) Jukka Pajarinen et al.   Acta Biomaterialia

Mutant MCP-1 protein delivery from layer-by-layer coatings on orthopedic implants to modulate inflammatory response

(2013) Michael Keeney et al.   BIOMATERIALS

Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles

(2013) Zhenyu Yao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Macrophages-Key cells in the response to wear debris from joint replacements

(2013) Christophe Nich et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Revision joint replacement, wear particles, and macrophage polarization

(2012) Allison J. Rao et al.   Acta Biomaterialia

Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss

(2012) Emmanuel Gibon et al.   BIOMATERIALS

Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium

(2012) Allison J. Rao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Fracture healing under healthy and inflammatory conditions

(2012) Lutz Claes et al.   Nature Reviews Rheumatology

Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles

(2011) Emmanuel Gibon et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Cellular chemotaxis induced by wear particles from joint replacements

(2010) Stuart B. Goodman et al.   BIOMATERIALS

Continuous Infusion of UHMWPE Particles Induces Increased Bone Macrophages and Osteolysis

(2010) Pei-Gen Ren et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Expression of markers of activity in cultured human osteoblasts: Effects of interleukin-4 and interleukin-13

(2010) Carl-Johan Silfverswärd et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

An in vivo murine model of continuous intramedullary infusion of polyethylene particles

(2008) Ting Ma et al.   BIOMATERIALS