Promotion of tumor progression by exosome transmission of circular RNA circSKA3

Circ-SKA3 upregulates ID3 expression by decoying miR-326 to accelerate the development of medulloblastoma

(2021) Xinde Zhao et al.   JOURNAL OF CLINICAL NEUROSCIENCE

A Neuroligin Isoform Translated by circNlgn Contributes to Cardiac Remodeling

(2021) William W. Du et al.   CIRCULATION RESEARCH

An antisense circular RNA circSCRIB enhances cancer progression by suppressing parental gene splicing and translation

(2021) Jian Ma et al.   MOLECULAR THERAPY

Exosome-transmitted miRNA-335-5p promotes colorectal cancer invasion and metastasis by facilitating EMT via targeting RASA1

(2021) Xuecheng Sun et al.   Molecular Therapy-Nucleic Acids

miR-1207-5p suppresses laryngeal squamous cell carcinoma progression by downregulating SKA3 and inhibiting epithelial-mesenchymal transition

(2021) Yongyan Wu et al.   Molecular Therapy-Oncolytics

Circ-SKA3 Enhances Doxorubicin Toxicity in AC16 Cells Through miR-1303/TLR4 Axis

(2021) Bin Li et al.   International Heart Journal

Exosome miR-155 Derived from Gastric Carcinoma Promotes Angiogenesis by Targeting the c-MYB/VEGF Axis of Endothelial Cells

(2020) Ting Deng et al.   Molecular Therapy-Nucleic Acids

The Circular RNA circSKA3 Binds Integrin β1 to Induce Invadopodium Formation Enhancing Breast Cancer Invasion

(2020) William W. Du et al.   MOLECULAR THERAPY

Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice

(2020) Yuto Nakamura et al.   MOLECULAR THERAPY

Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

(2020) Chenfei Zhou et al.   CELL DEATH AND DIFFERENTIATION

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1–AKT axis-mediated glycolysis

(2020) Wei Gao et al.   Cell Death & Disease

YAP Circular RNA, circYap, Attenuates Cardiac Fibrosis via Binding with Tropomyosin-4 and Gamma-Actin Decreasing Actin Polymerization

(2020) Nan Wu et al.   MOLECULAR THERAPY

Exosome mediated miR-29 transfer reduces muscle atrophy and kidney fibrosis in mice

(2019) Haidong Wang et al.   MOLECULAR THERAPY

CircRNA.33186 Contributes to the Pathogenesis of Osteoarthritis by Sponging miR-127-5p

(2019) Zhi-bin Zhou et al.   MOLECULAR THERAPY

Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in osteosarcoma chemo-resistance

(2019) Kun-Peng Zhu et al.   MOLECULAR THERAPY

Translation of yes-associated protein (YAP) was antagonized by its circular RNA via suppressing the assembly of the translation initiation machinery

(2019) Nan Wu et al.   CELL DEATH AND DIFFERENTIATION

circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer

(2019) Yuting Sang et al.   MOLECULAR THERAPY

Angiotensin II inhibits apoptosis of mouse aortic smooth muscle cells through regulating the circNRG-1/miR-193b-5p/NRG-1 axis

(2019) Yan Sun et al.   Cell Death & Disease

Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective

(2019) Laura Santer et al.   MOLECULAR THERAPY

Peripheral circulating exosomes-mediated delivery of miR-155 as a novel mechanism for acute lung inflammation

(2019) Kangfeng Jiang et al.   MOLECULAR THERAPY

The circular RNA circ-Ccnb1 dissociates Ccnb1/Cdk1 complex suppressing cell invasion and tumorigenesis

(2019) Ling Fang et al.   CANCER LETTERS

ncRNA-Encoded Peptides or Proteins and Cancer

(2019) Jizhong Wang et al.   MOLECULAR THERAPY

Interleukin-10 Deficiency Alters Endothelial Progenitor Cell–Derived Exosome Reparative Effect on Myocardial Repair via Integrin-Linked Kinase Enrichment

(2019) Yujia Yue et al.   CIRCULATION RESEARCH

circCAMSAP1 Promotes Tumor Growth in Colorectal Cancer via the miR-328-5p/E2F1 Axis

(2019) Chi Zhou et al.   MOLECULAR THERAPY

Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses

(2018) Duo Zhang et al.   MOLECULAR THERAPY

The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/ FAM65B pathway

(2018) Lu-Yu Zhou et al.   CELL DEATH AND DIFFERENTIATION

Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes

(2018) Yajun Chen et al.   CELL DEATH AND DIFFERENTIATION

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

An Unchartered Journey for Ribosomes: Circumnavigating Circular RNAs to Produce Proteins

(2017) Deirdre C. Tatomer et al.   MOLECULAR CELL

Sensing Self and Foreign Circular RNAs by Intron Identity

(2017) Y. Grace Chen et al.   MOLECULAR CELL

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

(2017) Zhen-Guo Yang et al.   MOLECULAR THERAPY

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

Identifying and Characterizing circRNA-Protein Interaction

(2017) William W Du et al.   Theranostics

Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

(2016) William W Du et al.   CELL DEATH AND DIFFERENTIATION

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Exosome isolation: a microfluidic road-map

(2015) A. Liga et al.   LAB ON A CHIP

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The pseudogene TUSC2P promotes TUSC2 function by binding multiple microRNAs

(2014) Zina Jeyapalan Rutnam et al.   Nature Communications

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion

(2011) C. C. Mader et al.   CANCER RESEARCH

Single-cell gene expression profiling using reverse transcription quantitative real-time PCR

(2010) Anders Ståhlberg et al.   METHODS

Versican G3 Promotes Mouse Mammary Tumor Cell Growth, Migration, and Metastasis by Influencing EGF Receptor Signaling

(2010) William Weidong Du et al.   PLoS One

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

(2009) Mark Shackleton et al.   CELL

Stable kinetochore–microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3

(2009) Thomas N Gaitanos et al.   EMBO JOURNAL