Silencing IQGAP1 alleviates hepatic fibrogenesis via blocking bone marrow mesenchymal stromal cell recruitment to fibrotic liver
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Silencing IQGAP1 alleviates hepatic fibrogenesis via blocking bone marrow mesenchymal stromal cell recruitment to fibrotic liver
Authors
Keywords
IQGAP1, sphingosine 1-phosphate receptor 3, bone marrow mesenchymal stromal cells, migration, liver fibrosis, Cdc42, Rac1, F-actin
Journal
Molecular Therapy-Nucleic Acids
Volume 27, Issue -, Pages 471-483
Publisher
Elsevier BV
Online
2021-12-18
DOI
10.1016/j.omtn.2021.12.020
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MicroRNA-124 inhibits hepatic stellate cells inflammatory cytokines secretion by targeting IQGAP1 through NF-κB pathway
- (2021) Junfa Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions
- (2021) Marisa P McGinley et al. LANCET
- Comprehensive profiling of circular RNA expressions reveals potential diagnostic and prognostic biomarkers in multiple myeloma
- (2020) Fan Zhou et al. BMC CANCER
- De novo variants in exomes of congenital heart disease patients identify risk genes and pathways
- (2020) Cigdem Sevim Bayrak et al. Genome Medicine
- IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation
- (2020) Haibo Wang et al. ANGIOGENESIS
- Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking
- (2020) Sayaka Ishihara et al. BMC BIOLOGY
- IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma
- (2020) Chun-fen Mo et al. BRITISH JOURNAL OF CANCER
- Migratory cues controlling B‐lymphocyte trafficking in human lymph nodes
- (2020) Saem Mul Park et al. IMMUNOLOGY AND CELL BIOLOGY
- Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration
- (2020) Alfonso Bolado-Carrancio et al. eLife
- Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells
- (2020) Yong Joo Park et al. Scientific Reports
- IQGAP1 mediates podocyte injury in diabetic kidney disease by regulating nephrin endocytosis
- (2019) Yipeng Liu et al. CELLULAR SIGNALLING
- IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling
- (2019) Wei Hu et al. Scientific Reports
- MicroRNA-26b-5p Inhibits Mouse Liver Fibrogenesis and Angiogenesis by Targeting PDGF Receptor-Beta
- (2019) Le Yang et al. Molecular Therapy-Nucleic Acids
- Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis
- (2019) David P. Sullivan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination
- (2018) Meilin Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- mDia1 and Cdc42 Regulate Activin B-Induced Migration of Bone Marrow-Derived Mesenchymal Stromal Cells
- (2018) Xueer Wang et al. STEM CELLS
- The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice
- (2017) Yongqing Wang et al. HEPATOLOGY
- Targeted Recycling of the Lateral Border Recycling Compartment Precedes Adherens Junction Dissociation during Transendothelial Migration
- (2016) Annette M. Gonzalez et al. AMERICAN JOURNAL OF PATHOLOGY
- HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis
- (2016) Na Chang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment
- (2016) Yamila I. Rodriguez et al. Frontiers in Oncology
- Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury
- (2016) Jieshi Xie et al. Scientific Reports
- Sphingosine 1-phosphate Receptor 2 Signaling Suppresses Macrophage Phagocytosis and Impairs Host Defense against Sepsis
- (2015) JinChao Hou et al. ANESTHESIOLOGY
- Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration
- (2015) Richard L. Watson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
- (2015) Evan W. Weber et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IQGAP1 Regulates Endothelial Barrier Function via EB1-Cortactin Cross Talk
- (2014) Y. Tian et al. MOLECULAR AND CELLULAR BIOLOGY
- Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
- (2014) Masayuki Nagahashi et al. Biomed Research International
- IQGAP1 links PDGF receptor-β signal to focal adhesions involved in vascular smooth muscle cell migration: role in neointimal formation after vascular injury
- (2013) Takashi Kohno et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver
- (2013) Chunsheng Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia
- (2012) M. Bhattacharya et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways
- (2011) Peter V. Usatyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload
- (2011) Mauro Sbroggiò et al. CARDIOVASCULAR RESEARCH
- IQGAP1 and its binding proteins control diverse biological functions
- (2011) Colin D. White et al. CELLULAR SIGNALLING
- ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1
- (2011) M. Sbroggio et al. JOURNAL OF CELL SCIENCE
- Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase
- (2011) Evgeny V. Berdyshev et al. PLoS One
- Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility
- (2010) Changyong Li et al. JOURNAL OF HEPATOLOGY
- Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis
- (2009) Changyong Li et al. JOURNAL OF HEPATOLOGY
- Activation of Signal Transducers and Activators of Transcription 3 and Focal Adhesion Kinase by Stromal Cell-Derived Factor 1 Is Required for Migration of Human Mesenchymal Stem Cells in Response to Tumor Cell-Conditioned Medium
- (2009) Hui Gao et al. STEM CELLS
- Proteomic analysis of CTGF-activated lung fibroblasts: identification of IQGAP1 as a key player in lung fibroblast migration
- (2008) Galina S. Bogatkevich et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now