Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study

(2022) Dinh S Bui et al.   Lancet Respiratory Medicine

Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

(2022) Alvar Agustí et al.   Lancet Respiratory Medicine

Genetics of chronic obstructive pulmonary disease: understanding the pathobiology and heterogeneity of a complex disorder

(2022) Michael H Cho et al.   Lancet Respiratory Medicine

Ambient air pollution exposure and chronic bronchitis in the Lifelines cohort

(2021) Dany Doiron et al.   THORAX

COPD awareness in the urban slums and rural areas around Pune city in India

(2021) Deesha Deepak Ghorpade et al.   npj Primary Care Respiratory Medicine

Pulmonary tuberculosis as a risk factor for chronic obstructive pulmonary disease: a systematic review and meta-analysis

(2021) Huanhuan Fan et al.   Annals of Translational Medicine

Impact of early life exposures on COPD in adulthood: A systematic review and meta‐analysis

(2021) Pengfei Duan et al.   RESPIROLOGY

Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

(2021) Surajit Dey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chronic obstructive pulmonary disease and lung cancer incidence in never smokers: a cohort study

(2020) Hye Yun Park et al.   THORAX

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Joan B Soriano et al.   Lancet Respiratory Medicine

Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

(2020) Peter Burney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Importance of Early COPD in Young Adults for Development of Clinical COPD. Findings from the Copenhagen General Population Study

(2020) Yunus Çolak et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic Airway Diseases Early Stratification (CADSET): a new ERS Clinical Research Collaboration

(2019) Alvar Agusti et al.   EUROPEAN RESPIRATORY JOURNAL

Health Effects of Household Solid Fuel Use: Findings from 11 Countries within the Prospective Urban and Rural Epidemiology Study

(2019) Perry Hystad et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Solid Fuel Use and Incident COPD in Chinese Adults: Findings from the China Kadoorie Biobank

(2019) Jiachen Li et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Geographic distribution of COPD prevalence in the World displayed by Geographic Information System maps

(2019) Ignacio Blanco et al.   EUROPEAN RESPIRATORY JOURNAL

Lung function trajectories in health and disease

(2019) Alvar Agusti et al.   Lancet Respiratory Medicine

Chronic Obstructive Pulmonary Disease Prevalence Among Adults Who Have Never Smoked, by Industry and Occupation — United States, 2013–2017

(2019) Girija Syamlal et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Management of Asthma COPD Overlap

(2019) Diego Jose Maselli et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Air pollution, lung function and COPD: results from the population-based UK Biobank study

(2019) Dany Doiron et al.   EUROPEAN RESPIRATORY JOURNAL

It is time for the world to take COPD seriously: a statement from the GOLD board of directors

(2019) David M.G. Halpin et al.   EUROPEAN RESPIRATORY JOURNAL

The occupations at increased risk of COPD: analysis of lifetime job-histories in the population-based UK Biobank Cohort

(2019) Sara De Matteis et al.   EUROPEAN RESPIRATORY JOURNAL

Primary human bronchial epithelial cell responses to diesel and biodiesel emissions at an air-liquid interface

(2019) Annalicia Vaughan et al.   TOXICOLOGY IN VITRO

Determinants of impaired lung function and lung cancer prediction among never-smokers in the UK Biobank cohort

(2019) Matthew T. Warkentin et al.   EBioMedicine

Significant chronic airway abnormalities in never‐smoking HIV ‐infected patients

(2019) G Besutti et al.   HIV MEDICINE

The GOLD Summit on chronic obstructive pulmonary disease in low- and middle-income countries

(2019) D. M. G. Halpin et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Airflow Obstruction and Use of Solid Fuels for Cooking or Heating. BOLD (Burden of Obstructive Lung Disease) Results

(2018) André F. S. Amaral et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association between Household Air Pollution Exposure and Chronic Obstructive Pulmonary Disease Outcomes in 13 Low- and Middle-Income Country Settings

(2018) Trishul Siddharthan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease

(2018) Fernando J. Martinez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ambient Air Pollution and Chronic Bronchitis in a Cohort of U.S. Women

(2018) Laura G. Hooper et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prevalence, risk factors and clinical correlates of COPD in a rural setting in Tanzania

(2018) Ng'weina Francis Magitta et al.   EUROPEAN RESPIRATORY JOURNAL

ERS/ATS workshop report on respiratory health effects of household air pollution

(2018) Akshay Sood et al.   EUROPEAN RESPIRATORY JOURNAL

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

(2018) Steven L. Taylor et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling

(2018) Junfei Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

(2018) Chen Wang et al.   LANCET

Prevalence and trend of COPD from 1995–1997 to 2006–2008: The HUNT study, Norway

(2018) Laxmi Bhatta et al.   RESPIRATORY MEDICINE

Letter from India

(2018) Sundeep Salvi   RESPIROLOGY

Prevalence of chronic obstructive pulmonary disease in the global population with HIV: a systematic review and meta-analysis

(2018) Jean Joel Bigna et al.   Lancet Global Health

COPD beyond smoking: new paradigm, novel opportunities

(2018) Alvar Agustí et al.   Lancet Respiratory Medicine

Solid Fuel Use and Risks of Respiratory Diseases: A Cohort Study of 280,000 Chinese Never-Smokers

(2018) Ka Hung Chan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic bronchitis and airflow obstruction is associated with household cooking fuel use among never-smoking women: a community-based cross-sectional study in Odisha, India

(2018) Asmi Panigrahi et al.   BMC PUBLIC HEALTH

Rural Residence and Poverty are Independent Risk Factors for COPD in the United States

(2018) Sarath Raju et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bacterial load and defective monocyte-derived macrophage bacterial phagocytosis in biomass-smoke COPD

(2018) Baishakhi Ghosh et al.   EUROPEAN RESPIRATORY JOURNAL

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Gregory A Roth et al.   LANCET

The effect of diesel emission exposure on primary human bronchial epithelial cells from a COPD cohort: N-acetylcysteine as a potential protective intervention

(2018) Annalicia Vaughan et al.   ENVIRONMENTAL RESEARCH

Differences between asthma–COPD overlap syndrome and adult-onset asthma

(2017) Minna Tommola et al.   EUROPEAN RESPIRATORY JOURNAL

Defining asthma–COPD overlap syndrome: a population-based study

(2017) Tobias N. Bonten et al.   EUROPEAN RESPIRATORY JOURNAL

Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma

(2017) Pieter-Paul Hekking et al.   EUROPEAN RESPIRATORY JOURNAL

Monocyte Adhesion, Migration, and Extracellular Matrix Breakdown Are Regulated by Integrin αVβ3 inMycobacterium tuberculosisInfection

(2017) Sara Brilha et al.   JOURNAL OF IMMUNOLOGY

Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking

(2017) Robert M. Reed et al.   PLoS One

COPD in HIV-Infected Patients: CD4 Cell Count Highly Correlated

(2017) Karine Risso et al.   PLoS One

A Low Peripheral Blood CD4/CD8 Ratio Is Associated with Pulmonary Emphysema in HIV

(2017) Matthew Triplette et al.   PLoS One

Dung biomass smoke activates inflammatory signaling pathways in human small airway epithelial cells

(2016) Claire E. McCarthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

¿Son adecuados los criterios diagnósticos del fenotipo mixto EPOC-asma en la enfermedad pulmonar obstructiva crónica por humo de biomasa?

(2016) Rafael Golpe et al.   ARCHIVOS DE BRONCONEUMOLOGIA

A Subnational Analysis of Mortality and Prevalence of COPD in China From 1990 to 2013

(2016) Peng Yin et al.   CHEST

Indoor Particulate Matter < 2.5 μm in Mean Aerodynamic Diameter and Carbon Monoxide Levels During the Burning of Mosquito Coils and Their Association With Respiratory Health

(2016) Devashri Salvi et al.   CHEST

Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam Study

(2016) Natalie Terzikhan et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

The Risk Factors and Characteristics of COPD Among Nonsmokers in Korea: An Analysis of KNHANES IV and V

(2016) Su Hwan Lee et al.   LUNG

Gene expression profiling of the effects of organic dust in lung epithelial and THP-1 cells reveals inductive effects on inflammatory and immune response genes

(2016) Vijay Boggaram et al.   PHYSIOLOGICAL GENOMICS

Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood

(2016) Jennifer L. Perret et al.   RESPIROLOGY

HIV and COPD: a conspiracy of risk factors

(2016) Umesh G. Lalloo et al.   RESPIROLOGY

Majority of never-smokers with airflow limitation do not have asthma: the Copenhagen General Population Study

(2016) Yunus Çolak et al.   THORAX

¿Son adecuados los criterios diagnósticos del fenotipo mixto EPOC-asma en la enfermedad pulmonar obstructiva crónica por humo de biomasa?

(2016) Rafael Golpe et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Sex differences of COPD phenotypes in nonsmoking patients

(2016) Yoonki Hong et al.   International Journal of Chronic Obstructive Pulmonary Disease

HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation

(2016) Kieran A. Brune et al.   PLoS One

Household Air Pollution Causes Dose-Dependent Inflammation and Altered Phagocytosis in Human Macrophages

(2015) Jamie Rylance et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary function in an international sample of HIV-positive, treatment-naïve adults with CD4 counts > 500 cells/μL: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial

(2015) KM Kunisaki et al.   HIV MEDICINE

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

(2015) Peter Lange et al.   NEW ENGLAND JOURNAL OF MEDICINE

Occupational COPD among Danish never-smokers: a population-based study

(2015) Else Toft Würtz et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Prevalence and determinants of chronic obstructive pulmonary disease in HIV infected patients in an African country with low level of tobacco smoking

(2015) Eric Walter Pefura-Yone et al.   RESPIRATORY MEDICINE

COPD prevalence in a north-eastern Italian general population

(2015) Massimo Guerriero et al.   RESPIRATORY MEDICINE

Prevalence and risk factors of COPD among never-smokers in two areas of Sweden – Occupational exposure to gas, dust or fumes is an important risk factor

(2015) Stig Hagstad et al.   RESPIRATORY MEDICINE

Global burden of COPD

(2015) José Luis López-Campos et al.   RESPIROLOGY

Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

(2015) W C Tan et al.   THORAX

Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea

(2015) Seok Jeong Lee et al.   International Journal of Chronic Obstructive Pulmonary Disease

The silent epidemic of COPD in Africa

(2015) Sundeep Salvi   Lancet Global Health

FEV1Decline in Patients with Chronic Obstructive Pulmonary Disease Associated with Biomass Exposure

(2014) Alejandra Ramírez-Venegas et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Distribución de fenotipos clínicos en pacientes con enfermedad pulmonar obstructiva crónica por humo de biomasa y por tabaco

(2014) Rafael Golpe et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Increased Risk of Radiographic Emphysema in HIV Is Associated With Elevated Soluble CD14 and Nadir CD4

(2014) Engi F. Attia et al.   CHEST

Occupational Risk Factors for COPD Phenotypes in the Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study

(2014) Brent Doney et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

COPD in nonsmokers: the biomass hypothesis - to be or not to be?

(2014) L. Gnatiuc et al.   EUROPEAN RESPIRATORY JOURNAL

Prevalence and correlates of airflow obstruction in  317 000 never-smokers in China

(2014) M. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Anti-cyclic citrullinated peptide (CCP) antibody in patients with wood-smoke-induced chronic obstructive pulmonary disease (COPD) without rheumatoid arthritis

(2014) Naseh Sigari et al.   RHEUMATOLOGY INTERNATIONAL

Comparison of clinical features between non-smokers with COPD and smokers with COPD: a retrospective observational study

(2014) Jing Zhang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Source of Biomass Cooking Fuel Determines Pulmonary Response to Household Air Pollution

(2013) Thomas E. Sussan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effect of Occupational Exposure to Vapors, Gases, Dusts, and Fumes on COPD Mortality Risk Among Swedish Construction Workers

(2013) Kjell Torén et al.   CHEST

Chronic Obstructive Pulmonary Disease in Non-smokers: A Case-Comparison Study

(2013) Paul Sexton et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

COPD phenotypes in biomass smoke- versus tobacco smoke-exposed Mexican women

(2013) P. G. Camp et al.   EUROPEAN RESPIRATORY JOURNAL

Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Gonghuan Yang et al.   LANCET

Characteristics and outcomes of chronic obstructive pulmonary disease in never smokers in Denmark: a prospective population study

(2013) Mette Thomsen et al.   Lancet Respiratory Medicine

Occupational Exposure to Dusts, Gases, and Fumes and Incidence of Chronic Obstructive Pulmonary Disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults

(2012) Amar J. Mehta et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airflow Obstruction in Never Smokers in Five Latin American Cities: The PLATINO Study

(2012) Rogelio Perez-Padilla et al.   ARCHIVES OF MEDICAL RESEARCH

Secondhand Smoke Exposure Predicted COPD and Other Tobacco-Related Mortality in a 17-Year Cohort Study in China

(2012) Yao He et al.   CHEST

COPD among non-smokers – Report from the Obstructive Lung Disease in Northern Sweden (OLIN) studies

(2012) Stig Hagstad et al.   RESPIRATORY MEDICINE

Prevalence of COPD and its association with socioeconomic status in China: Findings from China Chronic Disease Risk Factor Surveillance 2007

(2011) Peng Yin et al.   BMC PUBLIC HEALTH

COPD in China

(2011) Xiaocong Fang et al.   CHEST

Effect of Bronchoconstriction on Airway Remodeling in Asthma

(2011) Christopher L. Grainge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Respiratory health effects of diesel particulate matter

(2011) ZORAN D. RISTOVSKI et al.   RESPIROLOGY

Respiratory disease associated with solid biomass fuel exposure in rural women and children: systematic review and meta-analysis

(2011) J. Y. T. Po et al.   THORAX

Risk Factors for Chronic Obstructive Pulmonary Disease in a European Cohort of Young Adults

(2010) Roberto de Marco et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

COPD in Never Smokers

(2010) Bernd Lamprecht et al.   CHEST

Association of Environmental Tobacco Smoke Exposure in Childhood With Early Emphysema in Adulthood Among Nonsmokers: The MESA-Lung Study

(2009) G. S. Lovasi et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

COPD in Chinese nonsmokers

(2009) Y. Zhou et al.   EUROPEAN RESPIRATORY JOURNAL

Recent trends in COPD prevalence in Spain: a repeated cross-sectional survey 1997-2007

(2009) J. B. Soriano et al.   EUROPEAN RESPIRATORY JOURNAL

Distinct clinical phenotypes of airways disease defined by cluster analysis

(2009) M. Weatherall et al.   EUROPEAN RESPIRATORY JOURNAL

Airway Obstruction Is Increased in Pneumocystis-Colonized Human Immunodeficiency Virus-Infected Outpatients

(2009) A. Morris et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Chronic obstructive pulmonary disease in non-smokers

(2009) Sundeep S Salvi et al.   LANCET

Proportional classifications of COPD phenotypes

(2008) S E Marsh et al.   THORAX