Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis

Targeting Ferroptosis to Treat Cardiovascular Diseases: A New Continent to Be Explored

(2021) Fangze Huang et al.   Frontiers in Cell and Developmental Biology

miR‑21/PTEN pathway mediates the cardioprotection of geniposide against oxidized low‑density�lipoprotein‑induced endothelial injury via suppressing oxidative stress and inflammatory response

(2020) Song Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

(2020) Xuexian Fang et al.   CIRCULATION RESEARCH

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Transferrin Receptor Is a Specific Ferroptosis Marker

(2020) Huizhong Feng et al.   Cell Reports

Inhibition of autophagy by geniposide protects against myocardial ischemia/reperfusion injury

(2020) Xuexiu Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection

(2020) Tanya Ravingerová et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors

(2020) Jinghan Zhu et al.   Oxidative Medicine and Cellular Longevity

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidative Property and Molecular Mechanisms Underlying Geniposide-Mediated Therapeutic Effects in Diabetes Mellitus and Cardiovascular Disease

(2019) Ning Li et al.   Oxidative Medicine and Cellular Longevity

Myocardial ischemia and coronary disease in heart failure

(2019) Beniamino R. Pagliaro et al.   HEART FAILURE REVIEWS

Guanine-rich RNA binding protein GRSF1 inhibits myoblast differentiation through repressing mitochondrial ROS production

(2019) Wenxin Yin et al.   EXPERIMENTAL CELL RESEARCH

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

(2019) Tae-Jun Park et al.   Cell Death & Disease

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

(2019) Eunhee Park et al.   Cell Death & Disease

Liproxstatin-1 protects the mouse myocardium against ischemia/reperfusion injury by decreasing VDAC1 levels and restoring GPX4 levels

(2019) Yansheng Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway

(2019) Ting Jiang et al.   TOXICOLOGY IN VITRO

Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes

(2018) Yuichi Baba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Geniposide prevents H2 O2 -induced oxidative damage in melanocytes by activating the PI3K-Akt signalling pathway

(2018) W. Lu et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Pathological Roles of Iron in Cardiovascular Disease

(2018) Motoi Kobayashi et al.   CURRENT DRUG TARGETS

Targeting of regulated necrosis in kidney disease

(2018) Diego Martin-Sanchez et al.   NEFROLOGIA

Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway

(2018) Xin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Trends in mortality and recurrent coronary heart disease events after an acute myocardial infarction among Medicare beneficiaries, 2001-2009

(2015) Todd M. Brown et al.   AMERICAN HEART JOURNAL

Redox- and non-redox-metal-induced formation of free radicals and their role in human disease

(2015) Marian Valko et al.   ARCHIVES OF TOXICOLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Trends in the Incidence and Mortality of Coronary Heart Disease in Asian Pacific Region

(2014) Chin Meng Khoo et al.   Journal of Atherosclerosis and Thrombosis

Cell Death and Inflammatory Bowel Diseases: Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium

(2014) Tiago Nunes et al.   Biomed Research International

Mechanisms of Mammalian Iron Homeostasis

(2012) Kostas Pantopoulos et al.   BIOCHEMISTRY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The Biology of the RNA Binding Protein Guanine-Rich Sequence Binding Factor 1

(2012) Christoph Ufer   CURRENT PROTEIN & PEPTIDE SCIENCE

Antithrombotic activities of aqueous extract fromGardenia jasminoidesand its main constituent

(2012) Hai-yan Zhang et al.   PHARMACEUTICAL BIOLOGY

Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development

(2008) C. Ufer et al.   GENES & DEVELOPMENT