Journal
JOURNAL OF BIOMECHANICS
Volume 49, Issue 2, Pages 193-204Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2015.12.015
Keywords
Hyperthermia; Hypertension; Low-Density Lipoprotein; Analytical Solution
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Funding
- UniNA
- Compagnia di San Paolo
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An analytical solution for Low-Density Lipoprotein transport through an arterial wall under hyperthermia conditions is established in this work. A four-layer model is used to characterize the arterial wall. Transport governing equations are obtained as a combination between Staverman-Kedem-Katchalsky membrane equations and volume-averaged porous media equations. Temperature and solute transport fields are coupled by means of Ludwig-Soret effect. Results are in excellent agreement with numerical and analytical literature data under isothermal conditions, and with numerical literature data for the hyperthermia case. Effects of hypertension combined with hyperthermia, are also analyzed in this work. (C) 2015 Elsevier Ltd. All rights reserved.
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