A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation

A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes

(2021) François Kroll et al.   eLife

Fli1+ cells transcriptional analysis reveals an Lmo2–Prdm16 axis in angiogenesis

(2021) Gianfranco Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Efficient Synthetic CRISPR RNA/Cas9-Based Mutagenesis for Rapid Cardiovascular Phenotypic Screening in F0 Zebrafish

(2021) Rachael E. Quick et al.   Frontiers in Cell and Developmental Biology

Regulation of mRNA export through API5 and nuclear FGF2 interaction

(2020) Seoung Min Bong et al.   NUCLEIC ACIDS RESEARCH

Assessing the Role of Rare Genetic Variation in Patients With Heart Failure

(2020) Gundula Povysil et al.   JAMA Cardiology

Advancing Personalized Medicine Through the Application of Whole Exome Sequencing and Big Data Analytics

(2019) Pawel Suwinski et al.   Frontiers in Genetics

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated with Cardiac Morphogenesis and Heart Failure Development

(2019) Nay Aung et al.   CIRCULATION

An omics perspective on drug target discovery platforms

(2019) Jussi Paananen et al.   BRIEFINGS IN BIOINFORMATICS

Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish

(2018) Jean E. Copper et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis

(2018) Emily J. Mercer et al.   DEVELOPMENTAL BIOLOGY

A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish

(2018) Roland S. Wu et al.   DEVELOPMENTAL CELL

An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination

(2018) Jason J Early et al.   eLife

A Review of Automated Microinjection of Zebrafish Embryos

(2018) Yuliang Zhao et al.   Micromachines

Little Fish, Big Data: Zebrafish as a Model for Cardiovascular and Metabolic Disease

(2017) Philipp Gut et al.   PHYSIOLOGICAL REVIEWS

HSPB7 is indispensable for heart development by modulating actin filament assembly

(2017) Tongbin Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity

(2017) Wern-Chir Liao et al.   PLoS Genetics

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

(2017) Ulrike Esslinger et al.   PLoS One

Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes

(2016) Alexa Burger et al.   DEVELOPMENT

Long Noncoding RNA LOC100129973 Suppresses Apoptosis by Targeting miR-4707-5p and miR-4767 in Vascular Endothelial Cells

(2016) Wei Lu et al.   Scientific Reports

LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration

(2016) Shu Meng et al.   Journal of the American Heart Association

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

LMO2 at 25 years: a paradigm of chromosomal translocation proteins

(2015) Jennifer Chambers et al.   Open Biology

New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes

(2014) M. Senni et al.   EUROPEAN HEART JOURNAL

GATA5 loss-of-function mutation in familial dilated cardiomyopathy

(2014) XIAN-LING ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

(2014) David Cook et al.   NATURE REVIEWS DRUG DISCOVERY

Fishing for Teratogens: A Consortium Effort for a Harmonized Zebrafish Developmental Toxicology Assay

(2014) Jonathan S. Ball et al.   TOXICOLOGICAL SCIENCES

Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis

(2013) Gabriel E. Rosenfeld et al.   DEVELOPMENTAL BIOLOGY

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias

(2013) F J Calero-Nieto et al.   ONCOGENE

A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function

(2013) Thomas Parker et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation

(2012) JY Gu et al.   Clinics

Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos

(2012) Omri Weiss et al.   DEVELOPMENTAL BIOLOGY

Prevalence and spectrum of GATA5 mutations associated with congenital heart disease

(2012) Jin-Qi Jiang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

GATA5 Loss-of-Function Mutation Responsible for the Congenital Ventriculoseptal Defect

(2012) Dong Wei et al.   PEDIATRIC CARDIOLOGY

A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy

(2011) Eric Villard et al.   EUROPEAN HEART JOURNAL

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay – Progress report on phase I

(2011) A.-L. Gustafson et al.   REPRODUCTIVE TOXICOLOGY

Left Ventricular Remodeling in Heart Failure

(2011) Marvin A. Konstam et al.   JACC-Cardiovascular Imaging

Common Variants in HSPB7 and FRMD4B Associated With Advanced Heart Failure

(2010) Thomas P. Cappola et al.   Circulation-Cardiovascular Genetics

Alternative promoter and GATA5 transcripts in mouse

(2009) Bohao Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY