Single-Dose Intra-Cartilage Delivery of Kartogenin Using a Cationic Multi-Arm Avidin Nanocarrier Suppresses Cytokine-Induced Osteoarthritis-Related Catabolism

Resveratrol and Curcumin Attenuate Ex Vivo Sugar-Induced Cartilage Glycation, Stiffening, Senescence, and Degeneration

(2021) Shikhar Mehta et al.   Cartilage

Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis

(2021) Mingzhuang Hou et al.   Cell Death & Disease

3D Printed Poly(ε-Caprolactone)/Meniscus Extracellular Matrix Composite Scaffold Functionalized With Kartogenin-Releasing PLGA Microspheres for Meniscus Tissue Engineering

(2021) Hao Li et al.   Frontiers in Bioengineering and Biotechnology

Management of Osteoarthritis: Expert Opinion on NSAIDs

(2021) Alberto Magni et al.   Pain and Therapy

A Systematic Review of Current Clinical Practice Guidelines on Intra-articular Hyaluronic Acid, Corticosteroid, and Platelet-Rich Plasma Injection for Knee Osteoarthritis: An International Perspective

(2021) Mark Phillips et al.   Orthopaedic Journal of Sports Medicine

Development of KA34 as a cartilage regenerative therapy for Osteoarthritis

(2020) K.A. Johnson et al.   OSTEOARTHRITIS AND CARTILAGE

Avidin grafted dextran nanostructure enables a month-long intra-discal retention

(2020) Erica K. Wagner et al.   Scientific Reports

Overcoming negatively charged tissue barriers: Drug delivery using cationic peptides and proteins

(2020) Armin Vedadghavami et al.   Nano Today

Recent advances in targeted drug delivery for treatment of osteoarthritis

(2020) Shikhar Mehta et al.   CURRENT OPINION IN RHEUMATOLOGY

Hyaluronic Acid-Based Shape-Memory Cryogel Scaffolds for Focal Cartilage Defect Repair

(2020) Tengfei He et al.   TISSUE ENGINEERING PART A

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

(2019) Shannon Brown et al.   Acta Biomaterialia

Osteoarthritis

(2019) David J Hunter et al.   LANCET

Intra-articular Injection of Kartogenin-Incorporated Thermogel Enhancing Osteoarthritis Treatment

(2019) Shao-Jie Wang et al.   Frontiers in Chemistry

Effects of cartilage-targeting moieties on nanoparticle biodistribution in healthy and osteoarthritic joints

(2019) Shannon B. Brown et al.   Acta Biomaterialia

Multi-arm Avidin nano-construct for intra-cartilage delivery of small molecule drugs

(2019) Tengfei He et al.   JOURNAL OF CONTROLLED RELEASE

Intra-articular injection of kartogenin-conjugated polyurethane nanoparticles attenuates the progression of osteoarthritis

(2018) Wenshuai Fan et al.   DRUG DELIVERY

Recent advances in kartogenin for cartilage regeneration

(2018) Gaorui Cai et al.   JOURNAL OF DRUG TARGETING

Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10

(2018) Ji Ye Kwon et al.   Scientific Reports

Cartilage penetrating cationic peptide carriers for applications in drug delivery to avascular negatively charged tissues

(2018) Armin Vedadghavami et al.   Acta Biomaterialia

Cartilage-targeting drug delivery: can electrostatic interactions help?

(2017) Ambika G. Bajpayee et al.   Nature Reviews Rheumatology

Hyaluronic Acid Hydrogel Functionalized with Self-Assembled Micelles of Amphiphilic PEGylated Kartogenin for the Treatment of Osteoarthritis

(2017) Mi-Lan Kang et al.   TISSUE ENGINEERING PART A

Kartogenin treatment prevented joint degeneration in a rodent model of osteoarthritis: A pilot study

(2016) Geetha Mohan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term

(2016) A.G. Bajpayee et al.   OSTEOARTHRITIS AND CARTILAGE

A rabbit model demonstrates the influence of cartilage thickness on intra-articular drug delivery and retention within cartilage

(2015) Ambika G. Bajpayee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

PEGylated Cationic Polylactides for Hybrid Biosynthetic Gene Delivery

(2015) Charles H. Jones et al.   MOLECULAR PHARMACEUTICS

Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis

(2015) Y. Li et al.   OSTEOARTHRITIS AND CARTILAGE

Full-thickness cartilage defects are repaired via a microfracture technique and intraarticular injection of the small-molecule compound kartogenin

(2015) Xingquan Xu et al.   ARTHRITIS RESEARCH & THERAPY

Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration

(2014) Mi Lan Kang et al.   BIOMATERIALS

Electrostatic interactions enable rapid penetration, enhanced uptake and retention of intra-articular injected avidin in rat knee joints

(2014) Ambika G. Bajpayee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes

(2014) Yohei Ono et al.   Cartilage

Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis

(2013) Ambika G. Bajpayee et al.   BIOMATERIALS

Progress in intra-articular therapy

(2013) Christopher H. Evans et al.   Nature Reviews Rheumatology

Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

(2013) Mickaël Hiligsmann et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

A Novel Designed Chitosan Based Hydrogel Which is Capable of Consecutively Controlled Release of TGF-Beta 1 and BMP-7

(2013) İbrahim YILMAZ et al.   Turkiye Klinikleri Tip Bilimleri Dergisi

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

A Stem Cell-Based Approach to Cartilage Repair

(2012) K. Johnson et al.   SCIENCE

Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis

(2011) Ichiro Sekiya et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines

(2011) Yihong CS Lu et al.   ARTHRITIS RESEARCH & THERAPY

Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion

(2010) I. PATY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Synovial fluid mesenchymal stem cells in health and early osteoarthritis: Detection and functional evaluation at the single-cell level

(2008) Elena A. Jones et al.   ARTHRITIS AND RHEUMATISM

Hyaluronan promotes the chondrocyte response to BMP-7

(2008) R.A. Andhare et al.   OSTEOARTHRITIS AND CARTILAGE

Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M

(2007) M. Durigova et al.   OSTEOARTHRITIS AND CARTILAGE