Metabolomic signature and mitochondrial dynamics outline the difference between vulnerability and resilience to chronic stress

Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone

(2021) Paola Brivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The coupling of RACK1 with the beta isoform of the glucocorticoid receptor promotes resilience to chronic stress exposure

(2021) Paola Brivio et al.   Neurobiology of Stress

Acute Stress Induces Cognitive Improvement in the Novel Object Recognition Task by Transiently Modulating Bdnf in the Prefrontal Cortex of Male Rats

(2020) Paola Brivio et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Effect of lurasidone treatment on chronic mild stress-induced behavioural deficits in male rats: The potential role for glucocorticoid receptor signalling

(2020) Francesca Calabrese et al.   JOURNAL OF PSYCHOPHARMACOLOGY

An integrated meta-analysis of peripheral blood metabolites and biological functions in major depressive disorder

(2020) Juncai Pu et al.   MOLECULAR PSYCHIATRY

Cerebral Mitochondrial Function and Cognitive Performance during Aging: A Longitudinal Study in NMRI Mice

(2020) Martina Reutzel et al.   Oxidative Medicine and Cellular Longevity

Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice

(2020) Tim L. Emmerzaal et al.   Translational Psychiatry

Chronic Restraint Stress Inhibits the Response to a Second Hit in Adult Male Rats: A Role for BDNF Signaling

(2020) Paola Brivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of chronic stress on energy metabolism

(2020) Michael A. van der Kooij   MOLECULAR AND CELLULAR NEUROSCIENCE

Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum

(2020) Peter J. Hamilton et al.   Scientific Reports

Alterations of Glutamatergic Markers in the Prefrontal Cortex of Serotonin Transporter Knockout Rats: A Developmental Timeline

(2019) Paola Brivio et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neurobiology of Resilience: Interface Between Mind and Body

(2019) Flurin Cathomas et al.   BIOLOGICAL PSYCHIATRY

Chronic vortioxetine treatment improves the responsiveness to an acute stress acting through the ventral hippocampus in a glucocorticoid-dependent way

(2019) Paola Brivio et al.   PHARMACOLOGICAL RESEARCH

Metabolomics meets machine learning: Longitudinal metabolite profiling in serum of normal versus overconditioned cows and pathway analysis

(2019) Morteza H. Ghaffari et al.   JOURNAL OF DAIRY SCIENCE

Hippocampal proteomic changes of susceptibility and resilience to depression or anxiety in a rat model of chronic mild stress

(2019) Min Tang et al.   Translational Psychiatry

Citrulline prevents age-related LTP decline in old rats

(2019) Antonin Ginguay et al.   Scientific Reports

Integrated metabolomics and lipidomics profiling of hippocampus reveal metabolite biomarkers in a rat model of chronic unpredictable mild stress-induced depression

(2019) Chunmei Geng et al.   Annals of Translational Medicine

The effects of chronic stress on the human brain: From neurotoxicity, to vulnerability, to opportunity

(2018) Sonia J. Lupien et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Mitochondria at the neuronal presynapse in health and disease

(2018) Michael J. Devine et al.   NATURE REVIEWS NEUROSCIENCE

Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

(2018) Ziqing Kong et al.   NUCLEIC ACIDS RESEARCH

Hippocampal metabolic differences implicate distinctions between physical and psychological stress in four rat models of depression

(2018) Lanxiang Liu et al.   Translational Psychiatry

Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study

(2018) Jun-Xi Pan et al.   Translational Psychiatry

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

(2018) Christoph Anacker et al.   NATURE

Acetyl-l-carnitine deficiency in patients with major depressive disorder

(2018) Carla Nasca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers for major depressive and bipolar disorders using metabolomics: A systematic review

(2018) Kellie MacDonald et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

(2017) Laura C. Graham et al.   Molecular Neurodegeneration

Mitochondrial diseases: the contribution of organelle stress responses to pathology

(2017) Anu Suomalainen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

(2017) Carla Nasca et al.   NEURON

Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases

(2017) Renee R. Handley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism

(2017) Kimberley D. Bruce et al.   Frontiers in Endocrinology

Bifidobacterium in the gut microbiota confer resilience to chronic social defeat stress in mice

(2017) Chun Yang et al.   Scientific Reports

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

(2016) Rosemary C. Bagot et al.   NEURON

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

(2016) Benedetta Bigio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy

(2015) Anne Hamacher-Brady et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of stress in the brain

(2015) Bruce S McEwen et al.   NATURE NEUROSCIENCE

Combined Metabolomics and Proteomics Analysis of Major Depression in an Animal Model: Perturbed Energy Metabolism in the Chronic Mild Stressed Rat Cerebellum

(2015) Wei-hua Shao et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Mitochondrial function in the brain links anxiety with social subordination

(2015) Fiona Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

(2014) R. Faria et al.   NEUROSCIENCE

Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress

(2014) Georgia E. Hodes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty Acids in Energy Metabolism of the Central Nervous System

(2014) Alexander Panov et al.   Biomed Research International

Glutamate and GABA imbalance promotes neuronal apoptosis in hippocampus after stress

(2014) Ce Yang   MEDICAL SCIENCE MONITOR

Glucose Regulates Hypothalamic Long-chain Fatty Acid Metabolism via AMP-activated Kinase (AMPK) in Neurons and Astrocytes

(2013) Bouchra Taïb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain

(2013) Peter Schönfeld et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Neuronal Responses to Physiological Stress

(2012) Konstantinos Kagias et al.   Frontiers in Genetics

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Mitochondrial involvement in psychiatric disorders

(2008) Ling Shao et al.   ANNALS OF MEDICINE

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism