Disruption of the Sjögren-Larsson Syndrome GeneAldh3a2in Mice Increases Keratinocyte Growth and Retards Skin Barrier Recovery

Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification

(2015) Takuya Kitamura et al.   BIOCHEMICAL JOURNAL

Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation

(2015) Yusuke Ohno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Method to Simultaneously Determine the Sphingosine 1-Phosphate Breakdown Product (2E)-Hexadecenal and Its Fatty Acid Derivatives Using Isotope-Dilution HPLC–Electrospray Ionization–Quadrupole/Time-of-Flight Mass Spectrometry

(2014) Corinna Neuber et al.   ANALYTICAL CHEMISTRY

Activation of the Kelch-like ECH-Associated Protein 1 (Keap1)/NF-E2-Related Factor 2 (Nrf2) Pathway through Covalent Modification of the 2-Alkenal Group of Aliphatic Electrophiles in Coriandrum sativum L.

(2014) Yumi Abiko et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dual Functions of theTrans-2-Enoyl-CoA Reductase TER in the Sphingosine 1-Phosphate Metabolic Pathway and in Fatty Acid Elongation

(2014) Takeshi Wakashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the phytosphingosine metabolic pathway leading to odd-numbered fatty acids

(2014) Natsuki Kondo et al.   Nature Communications

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway

(2013) Aya Ohkuni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1

(2013) Takuya Kitamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of lipids in the formation and maintenance of the cutaneous permeability barrier

(2013) Kenneth R. Feingold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fatty aldehyde and fatty alcohol metabolism: Review and importance for epidermal structure and function

(2013) William B. Rizzo   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids

(2013) Akio Kihara   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production

(2013) T. Sassa et al.   MOLECULAR AND CELLULAR BIOLOGY

Nrf2 links epidermal barrier function with antioxidant defense

(2012) Matthias Schäfer et al.   EMBO Molecular Medicine

Lack of Plakoglobin in Epidermis Leads to Keratoderma

(2012) Deqiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Sjögren-Larsson Syndrome Gene Encodes a Hexadecenal Dehydrogenase of the Sphingosine 1-Phosphate Degradation Pathway

(2012) Kanae Nakahara et al.   MOLECULAR CELL

PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

(2012) Anaïs Grall et al.   NATURE GENETICS

The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism

(2012) Yoichiro Mitsuishi et al.   Frontiers in Oncology

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Altered lipid profiles in the stratum corneum of Sjögren-Larsson syndrome

(2011) Kimiko Nakajima et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Ichthyosis in the Sjögren-Larsson syndrome

(2010) S. Jagell et al.   CLINICAL GENETICS

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2

(2009) Henryk Dreger et al.   CARDIOVASCULAR RESEARCH

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

(2008) Angel Catalá   CHEMISTRY AND PHYSICS OF LIPIDS

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

(2008) Satori A Marchitti et al.   Expert Opinion on Drug Metabolism & Toxicology

Omega-O-acylceramide, a lipid essential for mammalian survival

(2008) Yoshikazu Uchida et al.   JOURNAL OF DERMATOLOGICAL SCIENCE