Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression

The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression

(2021) Emma Rhodes et al.   JOURNAL OF ALZHEIMERS DISEASE

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

(2021) Jacob W. Vogel et al.   NATURE MEDICINE

Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data

(2021) Arman Eshaghi et al.   Nature Communications

Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes

(2021) Junhao Wen et al.   MEDICAL IMAGE ANALYSIS

A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure

(2021) Zhijian Yang et al.   Nature Communications

How well do elderly patients with major depressive disorder respond to antidepressants: a systematic review and single-group meta-analysis

(2020) Katharina Gutsmiedl et al.   BMC Psychiatry

Cognitive functioning and lifetime Major Depressive Disorder in UK Biobank

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Late-life related subtypes of depression – a data-driven approach on cognitive domains and physical frailty

(2020) Astrid Lugtenburg et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

(2020) Xueyi Shen et al.   Nature Communications

Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies

(2020) Na Cai et al.   HUMAN MOLECULAR GENETICS

Subtyping late-life depression according to inflammatory and metabolic dysregulation: a prospective study

(2020) K. J. E. Kokkeler et al.   PSYCHOLOGICAL MEDICINE

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Depression in neurodegenerative diseases: Common mechanisms and current treatment options

(2019) Ciaran P.C. Galts et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mechanisms and treatment of late-life depression

(2019) George S. Alexopoulos   Translational Psychiatry

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Prevalence of Depression in the Community from 30 Countries between 1994 and 2014

(2018) Grace Y. Lim et al.   Scientific Reports

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

(2018) Alexandra L Young et al.   Nature Communications

HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework

(2017) Erdem Varol et al.   NEUROIMAGE

Systematic review and meta-analysis of genetic studies of late-life depression

(2017) Ruby S.M. Tsang et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

fMRI clustering and false-positive rates

(2017) Robert W. Cox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A continuum of genetic liability for minor and major depression

(2017) E C Corfield et al.   Translational Psychiatry

Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

(2017) Xueyi Shen et al.   Scientific Reports

White matter hyperintensities and imaging patterns of brain ageing in the general population

(2016) Mohamad Habes et al.   BRAIN

CHIMERA: Clustering of Heterogeneous Disease Effects via Distribution Matching of Imaging Patterns

(2016) Aoyan Dong et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Impact of Depressive Symptoms on Conversion from Mild Cognitive Impairment Subtypes to Alzheimer’s Disease: A Community-Based Longitudinal Study

(2016) Jiro Kida et al.   JOURNAL OF ALZHEIMERS DISEASE

Resting-state connectivity biomarkers define neurophysiological subtypes of depression

(2016) Andrew T Drysdale et al.   NATURE MEDICINE

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

(2016) Karla L Miller et al.   NATURE NEUROSCIENCE

MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection

(2016) Jimit Doshi et al.   NEUROIMAGE

Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer’s disease

(2016) Xiuming Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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(2016)   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men

(2016) Marina Daskalopoulou et al.   PLoS One

The relationship between depression and frailty syndrome: a systematic review

(2014) Cristina Buigues et al.   AGING & MENTAL HEALTH

Diffusion tensor imaging studies in late-life depression: systematic review and meta-analysis

(2014) Ming-Ching Wen et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Brain grey matter volume alterations in late-life depression

(2014) Mingying Du et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies

(2013) Breno S. Diniz et al.   BRITISH JOURNAL OF PSYCHIATRY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

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Magnetic Resonance Imaging in Late-Life Depression

(2012) Claire E. Sexton et al.   ARCHIVES OF GENERAL PSYCHIATRY

Association of microstructural white matter abnormalities with cognitive dysfunction in geriatric patients with major depression

(2012) Gilberto Sousa Alves et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Depression and Risk of Stroke Morbidity and Mortality

(2011) An Pan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

N4ITK: Improved N3 Bias Correction

(2010) Nicholas J Tustison et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Age- and gender-specific prevalence of depression in latest-life – Systematic review and meta-analysis

(2010) M. Luppa et al.   JOURNAL OF AFFECTIVE DISORDERS

DRAMMS: Deformable registration via attribute matching and mutual-saliency weighting

(2010) Yangming Ou et al.   MEDICAL IMAGE ANALYSIS

Depression severity is correlated to the integrity of white matter fiber tracts in late-onset major depression

(2010) Rikke Beese Dalby et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Diffuse Microstructural Abnormalities of Normal-Appearing White Matter in Late Life Depression: A Diffusion Tensor Imaging Study

(2009) Joshua S. Shimony et al.   BIOLOGICAL PSYCHIATRY

Longitudinal progression of Alzheimer's-like patterns of atrophy in normal older adults: the SPARE-AD index

(2009) C. Davatzikos et al.   BRAIN

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hippocampal Morphology and Distinguishing Late-Onset From Early-Onset Elderly Depression

(2007) Martina Ballmaier et al.   AMERICAN JOURNAL OF PSYCHIATRY

Tract probability maps in stereotaxic spaces: Analyses of white matter anatomy and tract-specific quantification

(2007) Kegang Hua et al.   NEUROIMAGE