Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice

Intermedin/adrenomedullin 2 polypeptide promotes adipose tissue browning and reduces high-fat diet-induced obesity and insulin resistance in mice

(2016) H Zhang et al.   INTERNATIONAL JOURNAL OF OBESITY

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

(2014) Yun Sok Lee et al.   CELL

Eicosapentaenoic Acid Protects against Palmitic Acid-Induced Endothelial Dysfunction via Activation of the AMPK/eNOS Pathway

(2014) Che-Hsin Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The synergistic effect of homocysteine and lipopolysaccharide on the differentiation and conversion of raw264.7 macrophages

(2014) Shanshan Gao et al.   Journal of Inflammation-London

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?

(2014) Michael James Kraakman et al.   Frontiers in Immunology

Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach

(2013) Tao Huang et al.   BMC GENOMICS

Intermedin protects against myocardial ischemia-reperfusion injury in diabetic rats

(2013) Hong Li et al.   Cardiovascular Diabetology

Intermedin inhibits macrophage foam-cell formation via tristetraprolin-mediated decay of CD36 mRNA

(2013) Xiao-Yan Dai et al.   CARDIOVASCULAR RESEARCH

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

(2013) Rémi Mounier et al.   Cell Metabolism

An unbalanced monocyte polarisation in peripheral blood and bone marrow of patients with type 2 diabetes has an impact on microangiopathy

(2013) G. P. Fadini et al.   DIABETOLOGIA

Hyperhomocysteinemia Promotes Insulin Resistance by Inducing Endoplasmic Reticulum Stress in Adipose Tissue

(2013) Yang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Intermedin Attenuates LPS-induced Inflammation in the Rat Testis

(2013) Lei Li et al.   PLoS One

Severe Hyperhomocysteinemia Promotes Bone Marrow–Derived and Resident Inflammatory Monocyte Differentiation and Atherosclerosis in LDLr/CBS-Deficient Mice

(2012) Daqing Zhang et al.   CIRCULATION RESEARCH

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Increased stability of phosphatase and tensin homolog by intermedin leading to scavenger receptor A inhibition of macrophages reduces atherosclerosis in apolipoprotein E-deficient mice

(2012) Xiao-Yan Dai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Extracellular signal-regulated kinase 1/2 activation is involved in intermedin1–53 attenuating myocardial oxidative stress injury induced by ischemia/reperfusion

(2012) Lei Zhao et al.   PEPTIDES

The pharmacology of Adrenomedullin 2/Intermedin

(2011) Yanguo Hong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Innate immunity, insulin resistance and type 2 diabetes

(2011) J. M. Fernández-Real et al.   DIABETOLOGIA

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

(2011) Sandra Galic et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

(2010) Zhenggang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis

(2009) Bilal Omar et al.   CELLULAR SIGNALLING

Hyperhomocysteinemia Promotes Inflammatory Monocyte Generation and Accelerates Atherosclerosis in Transgenic Cystathionine β-Synthase–Deficient Mice

(2009) Daqing Zhang et al.   CIRCULATION

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

(2009) Shigeki Sugii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased plasma levels of the mature and intermediate forms of adrenomedullin in obesity

(2009) Ikuo Nomura et al.   REGULATORY PEPTIDES

Adipose Tissue Macrophages, Low Grade Inflammation and Insulin Resistance in Human Obesity

(2008) Leonie Heilbronn et al.   CURRENT PHARMACEUTICAL DESIGN

Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro

(2008) Y. Li et al.   DIABETES

Intermedin (adrenomedullin-2): a novel counter-regulatory peptide in the cardiovascular and renal systems

(2007) D Bell et al.   BRITISH JOURNAL OF PHARMACOLOGY