Coordinative Modulation of Chlorothricin Biosynthesis by Binding of the Glycosylated Intermediates and End Product to a Responsive Regulator ChlF1

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins

(2015) Zhenhua Tian et al.   Nature Chemical Biology

Spirotetronate Polyketides as Leads in Drug Discovery

(2014) Michelle H. Lacoske et al.   JOURNAL OF NATURAL PRODUCTS

A γ-butyrolactone-sensing activator/repressor, JadR3, controls a regulatory mini-network for jadomycin biosynthesis

(2014) Zhengzhong Zou et al.   MOLECULAR MICROBIOLOGY

Characterization of AvaR1, an autoregulator receptor that negatively controls avermectins production in a high avermectin-producing strain

(2013) Jian-Bo Wang et al.   BIOTECHNOLOGY LETTERS

Deglycosylation as a Mechanism of Inducible Antibiotic Resistance Revealed Using a Global Relational Tree for One-Component Regulators

(2013) Leslie Cuthbertson et al.   CHEMISTRY & BIOLOGY

The TetR Family of Regulators

(2013) L. Cuthbertson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase

(2013) Sumei Li et al.   ORGANIC LETTERS

Nomimicin, a new spirotetronate-class polyketide from an actinomycete of the genus Actinomadura

(2012) Yasuhiro Igarashi et al.   JOURNAL OF ANTIBIOTICS

A Two-Step Mechanism for the Activation of Actinorhodin Export and Resistance in Streptomyces coelicolor

(2012) Y. Xu et al.   mBio

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A finely tuned regulatory circuit of the nicotinic acid degradation pathway in Pseudomonas putida

(2011) José Ignacio Jiménez et al.   ENVIRONMENTAL MICROBIOLOGY

A novel role of ‘pseudo’γ-butyrolactone receptors in controlling γ-butyrolactone biosynthesis in Streptomyces

(2011) Juan Wang et al.   MOLECULAR MICROBIOLOGY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

Insights into Bacterial 6-Methylsalicylic Acid Synthase and Its Engineering to Orsellinic Acid Synthase for Spirotetronate Generation

(2010) Wei Ding et al.   CHEMISTRY & BIOLOGY

“Pseudo” γ-Butyrolactone Receptors Respond to Antibiotic Signals to Coordinate Antibiotic Biosynthesis

(2010) Gangming Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis

(2009) R. Li et al.   MICROBIOLOGY-SGM

PolY, a transcriptional regulator with ATPase activity, directly activates transcription ofpolRin polyoxin biosynthesis inStreptomyces cacaoi

(2009) Rui Li et al.   MOLECULAR MICROBIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator

(2009) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type II Thioesterase ScoT, Associated with Streptomyces coelicolor A3(2) Modular Polyketide Synthase Cpk, Hydrolyzes Acyl Residues and Has a Preference for Propionate

(2008) M. Kotowska et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY