A Deafness- and Diabetes-associated tRNA Mutation Causes Deficient Pseudouridinylation at Position 55 in tRNAGluand Mitochondrial Dysfunction

The defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

(2016) Danni Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Hypertension-Associated tRNAAlaMutation Alters tRNA Metabolism and Mitochondrial Function

(2016) Pingping Jiang et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxidative stress in inherited mitochondrial diseases

(2015) Genki Hayashi et al.   FREE RADICAL BIOLOGY AND MEDICINE

The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation

(2015) Pingping Jiang et al.   HUMAN MOLECULAR GENETICS

Mitochondrial tRNASer(UCN) variants in 2651 Han Chinese subjects with hearing loss

(2015) Xiaowen Tang et al.   MITOCHONDRION

Maternally inherited diabetes is associated with a homoplasmic T10003C mutation in the mitochondrial tRNAGly gene

(2015) Hao Liu et al.   MITOCHONDRION

A peep into mitochondrial disorder: multifaceted from mitochondrial DNA mutations to nuclear gene modulation

(2015) Chao Chen et al.   Protein & Cell

Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier

(2015) Ana Martínez-Zamora et al.   PLoS One

Leber's hereditary optic neuropathy caused by the homoplasmic ND1 m.3635G>A mutation in nine Han Chinese families

(2014) Juanjuan Zhang et al.   MITOCHONDRION

A deafness-associated tRNAHismutation alters the mitochondrial function, ROS production and membrane potential

(2014) Shasha Gong et al.   NUCLEIC ACIDS RESEARCH

A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs

(2014) T. Suzuki et al.   NUCLEIC ACIDS RESEARCH

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

(2014) M. Picard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multilevel functional and structural defects induced by two pathogenic mitochondrial tRNA mutations

(2013) Meng Wang et al.   BIOCHEMICAL JOURNAL

Coronary heart disease is associated with a mutation in mitochondrial tRNA

(2013) Zidong Jia et al.   HUMAN MOLECULAR GENETICS

Effect of mtDNA point mutations on cellular bioenergetics

(2012) Joanna Szczepanowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness

(2012) Nuno Raimundo et al.   CELL

Mitochondrial tRNA mutations associated with deafness

(2012) Jing Zheng et al.   MITOCHONDRION

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases

(2011) Tsutomu Suzuki et al.   Annual Review of Genetics

Maternally Inherited Essential Hypertension Is Associated With the Novel 4263A>G Mutation in the Mitochondrial tRNA Ile Gene in a Large Han Chinese Family

(2011) Shiwen Wang et al.   CIRCULATION RESEARCH

Mitochondrial Dysfunction andβ-Cell Failure in Type 2 Diabetes Mellitus

(2011) Zhongmin Alex Ma et al.   Experimental Diabetes Research

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial DNA disease: new options for prevention

(2011) L. Craven et al.   HUMAN MOLECULAR GENETICS

Bcl-xLregulates mitochondrial energetics by stabilizing the inner membrane potential

(2011) Ying-bei Chen et al.   JOURNAL OF CELL BIOLOGY

Maternally transmitted late-onset non-syndromic deafness is associated with the novel heteroplasmic T12201C mutation in the mitochondrial tRNAHis gene

(2011) X. Yan et al.   JOURNAL OF MEDICAL GENETICS

Nucleotide modifications and tRNA anticodon-mRNA codon interactions on the ribosome

(2011) O. Allner et al.   RNA

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

(2010) Mary-Elizabeth Patti et al.   ENDOCRINE REVIEWS

The heteroplasmic m.14709T>C mutation in the tRNAGlu gene in two Tunisian families with mitochondrial diabetes

(2010) Najla Mezghani et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Human Mitochondrial Leucyl-tRNA Synthetase Corrects Mitochondrial Dysfunctions Due to the tRNALeu(UUR) A3243G Mutation, Associated with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Symptoms and Diabetes

(2010) R. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus

(2010) Kazuo Ishida et al.   NUCLEIC ACIDS RESEARCH

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial haplotypes may modulate the phenotypic manifestation of the deafness-associated 12S rRNA 1555A>G mutation

(2009) Jianxin Lu et al.   MITOCHONDRION

Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation

(2008) R. Murphy et al.   DIABETIC MEDICINE

Evaluation of chemiluminescence and flow cytometry as tools in assessing production of hydrogen peroxide and superoxide anion in human spermatozoa

(2008) Reda Mahfouz et al.   FERTILITY AND STERILITY

Mitochondrial tRNAThr G15927A mutation may modulate the phenotypic manifestation of ototoxic 12S rRNA A1555G mutation in four Chinese families

(2008) Xinjian Wang et al.   Pharmacogenetics and Genomics