Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis

Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria

(2016) Valérie Guillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis

(2016) Misty L. Kuhn et al.   ACS Infectious Diseases

Protein Phosphatases of Pathogenic Bacteria: Role in Physiology and Virulence

(2015) Andaleeb Sajid et al.   Annual Review of Microbiology

Proteome-wide lysine acetylation profiling of the human pathogen Mycobacterium tuberculosis

(2015) Longxiang Xie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog

(2015) Suereta Fortuin et al.   Frontiers in Microbiology

Phosphorylation of Mycobacterium tuberculosis ParB Participates in Regulating the ParABS Chromosome Segregation System

(2015) Grégory Baronian et al.   PLoS One

The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria

(2014) Sabine Gavalda et al.   CHEMISTRY & BIOLOGY

Mycolic Acids: Structures, Biosynthesis, and Beyond

(2014) Hedia Marrakchi et al.   CHEMISTRY & BIOLOGY

Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

(2014) Catherine Vilchèze et al.   PLoS Pathogens

Mechanism and Regulation of Mycobactin Fatty Acyl-AMP Ligase FadD33

(2013) Olivia Vergnolle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32

(2013) S. A. Stanley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenylating Enzymes in Mycobacterium tuberculosis as Drug Targets

(2012) Benjamin P. Duckworth et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Phosphorylation of Mycobacterial PcaA Inhibits Mycolic Acid Cyclopropanation

(2012) Rosa Milagros Corrales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quinolinyl Pyrimidines: Potent Inhibitors of NDH-2 as a Novel Class of Anti-TB Agents

(2012) Pravin S. Shirude et al.   ACS Medicinal Chemistry Letters

Identifying Vulnerable Pathways in Mycobacterium tuberculosis by Using a Knockdown Approach

(2011) Paul Carroll et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system

(2011) Nawel Slama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain

(2011) Elke E Noens et al.   BMC BIOTECHNOLOGY

Phosphorylation of Mycobacterium tuberculosis Ser/Thr Phosphatase by PknA and PknB

(2011) Andaleeb Sajid et al.   PLoS One

Conditional Gene Expression in Mycobacterium abscessus

(2011) Mélanie Cortes et al.   PLoS One

Phosphorylation of Enoyl-Acyl Carrier Protein Reductase InhA Impacts Mycobacterial Growth and Survival

(2010) Shazia Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of theMycobacterium tuberculosisβ-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis

(2010) Romain Veyron-Churlet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis

(2010) Virginie Molle et al.   MOLECULAR MICROBIOLOGY

Division and cell envelope regulation by Ser/Thr phosphorylation:Mycobacteriumshows the way

(2010) Virginie Molle et al.   MOLECULAR MICROBIOLOGY

Development of a repressible mycobacterial promoter system based on two transcriptional repressors

(2010) Francesca Boldrin et al.   NUCLEIC ACIDS RESEARCH

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases

(2010) S. Prisic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An improved method to unravel phosphoacceptors in Ser/Thr protein kinase-phosphorylated substrates

(2010) Virginie Molle et al.   PROTEOMICS

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis

(2009) Mathieu Léger et al.   CHEMISTRY & BIOLOGY

The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids inMycobacterium tuberculosis

(2009) Sabine Gavalda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pristinamycin-inducible gene regulation in mycobacteria

(2009) Francesca Forti et al.   JOURNAL OF BIOTECHNOLOGY

Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression

(2009) Parvinder Kaur et al.   PLoS One

Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State

(2008) B. Zuber et al.   JOURNAL OF BACTERIOLOGY

TheMycobacterium tuberculosisβ-Ketoacyl-Acyl Carrier Protein Synthase III Activity Is Inhibited by Phosphorylation on a Single Threonine Residue

(2008) Romain Veyron-Churlet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential

(2007) Annemarie Wehenkel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS