Regulation of Cancer Cell Behavior by the Small GTPase Rab13

Rab13 Traffics on Vesicles Independent of Prenylation

(2016) Maria S. Ioannou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis

(2016) Yi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal–epithelial transition

(2015) Lin-Yan Zhu et al.   CANCER LETTERS

ANXA1Ac2-26 peptide reduces ID1 expression in cervical carcinoma cultures

(2015) Janesly Prates et al.   GENE

Ionizing radiation induces neuronal differentiation of Neuro-2a cells via PI3-kinase and p53-dependent pathways

(2015) Hyeon Soo Eom et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior

(2015) Maria S. Ioannou et al.   JOURNAL OF CELL BIOLOGY

Regulation of mammalian Ste20 (Mst) kinases

(2015) Sonali J. Rawat et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

(2014) Patricia A.J. Muller et al.   CANCER CELL

Bioinformatics analysis reveals disturbance mechanism of MAPK signaling pathway and cell cycle in Glioblastoma multiforme

(2014) Wusheng Li et al.   GENE

Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients

(2014) Kai Zhang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation

(2014) Ge Zhou et al.   MOLECULAR CELL

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking

(2014) A. Nishikimi et al.   Science Signaling

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

(2014) H. Kobayashi et al.   Biology Open

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins

(2013) Ayuko Sakane et al.   GENES TO CELLS

Protein Kinase D1-mediated Phosphorylations Regulate Vasodilator-stimulated Phosphoprotein (VASP) Localization and Cell Migration

(2013) Heike R. Döppler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thyroid Cancer Cell Resistance to gefitinib Depends on the Constitutive Oncogenic Activation of the ERK Pathway

(2013) Francesco Frasca et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Overexpression of ANXA1 in Penile Carcinomas Positive for High-Risk HPVs

(2013) Marilia Freitas Calmon et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy

(2012) S. K. McBrayer et al.   BLOOD

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

(2012) Tobias H Klöpper et al.   BMC BIOLOGY

Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells

(2012) Han Sang Kim et al.   BMC GENOMICS

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development

(2012) Ayuko Sakane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration

(2012) Elena Rainero et al.   JOURNAL OF CELL BIOLOGY

Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion

(2012) Y. Artemenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Rab13-dependent Trafficking of RhoA Is Required for Directional Migration and Angiogenesis

(2011) Chuanshen Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MICAL-like1 mediates epidermal growth factor receptor endocytosis

(2011) Nancy Abou-Zeid et al.   MOLECULAR BIOLOGY OF THE CELL

Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton

(2011) Andrea L. Marat et al.   MOLECULAR BIOLOGY OF THE CELL

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

(2011) X Ma et al.   MOLECULAR PSYCHIATRY

Initial steps of metastasis: Cell invasion and endothelial transmigration

(2011) Franziska van Zijl et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Frequent hyperphosphorylation of AS160 in breast cancer

(2010) Xiao-Hua Jiang et al.   CANCER BIOLOGY & THERAPY

Integrin Signaling Switches the Cytoskeletal and Exocytic Machinery that Drives Neuritogenesis

(2010) Stephanie L. Gupton et al.   DEVELOPMENTAL CELL

The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery

(2010) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

(2010) Shin-ichiro Yoshimura et al.   JOURNAL OF CELL BIOLOGY

p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma

(2010) Brendan Doyle et al.   JOURNAL OF PATHOLOGY

The Connecdenn DENN Domain: A GEF for Rab35 Mediating Cargo-Specific Exit from Early Endosomes

(2010) Patrick D. Allaire et al.   MOLECULAR CELL

Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells

(2010) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes

(2009) Koko Katagiri et al.   EMBO JOURNAL

Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking

(2009) Mathilde Chaineau et al.   FEBS LETTERS

Rab13 Regulates Neurite Outgrowth in PC12 Cells through Its Effector Protein, JRAB/MICAL-L2

(2009) A. Sakane et al.   MOLECULAR AND CELLULAR BIOLOGY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Filamins Regulate Cell Spreading and Initiation of Cell Migration

(2009) Massimiliano Baldassarre et al.   PLoS One

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

(2009) J. P. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Emerging Role of the Hippo Pathway in Cell Contact Inhibition, Organ Size Control, and Cancer Development in Mammals

(2008) Qi Zeng et al.   CANCER CELL

Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma

(2008) Wenxi Li et al.   INTERNATIONAL JOURNAL OF CANCER

Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells

(2008) Rita L. Nokes et al.   JOURNAL OF CELL BIOLOGY

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS

Involvement of Actinin-4 in the Recruitment of JRAB/MICAL-L2 to Cell-Cell Junctions and the Formation of Functional Tight Junctions

(2008) H. Nakatsuji et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions

(2008) Stavroula Mili et al.   NATURE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

The Interaction of JRAB/MICAL-L2 with Rab8 and Rab13 Coordinates the Assembly of Tight Junctions and Adherens Junctions

(2007) Rie Yamamura et al.   MOLECULAR BIOLOGY OF THE CELL