Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site

Physiological Roles of Acid-Base Sensors

(2015) Lonny R. Levin et al.   Annual Review of Physiology

Structure, mechanism, and regulation of soluble adenylyl cyclases — similarities and differences to transmembrane adenylyl cyclases

(2014) Clemens Steegborn   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Central role of soluble adenylyl cyclase and cAMP in sperm physiology

(2014) Mariano G. Buffone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice

(2014) George G. Holz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bithionol inhibits ovarian cancer cell growth In Vitro- studies on mechanism(s) of action

(2014) Vijayalakshmi N Ayyagari et al.   BMC CANCER

Crystal Structure of Human Soluble Adenylate Cyclase Reveals a Distinct, Highly Flexible Allosteric Bicarbonate Binding Pocket

(2014) Susanne M. Saalau-Bethell et al.   ChemMedChem

Structural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes - implications for cyclase catalysis and evolution

(2014) Silke Kleinboelting et al.   FEBS Journal

Advances in targeting cyclic nucleotide phosphodiesterases

(2014) Donald H. Maurice et al.   NATURE REVIEWS DRUG DISCOVERY

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate

(2014) S. Kleinboelting et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification, crystallization and preliminary X-ray diffraction analysis of a mammalian type 10 adenylyl cyclase

(2014) Silke Kleinboelting et al.   Acta Crystallographica Section F-Structural Biology Communications

Better models by discarding data?

(2013) K. Diederichs et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Biological roles of cAMP: variations on a theme in the different kingdoms of life

(2013) Juana M. Gancedo   BIOLOGICAL REVIEWS

CO2/HCO3−- and Calcium-regulated Soluble Adenylyl Cyclase as a Physiological ATP Sensor

(2013) Jonathan H. Zippin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS

(2012) Michael Krug et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

(2012) Uwe Mueller et al.   JOURNAL OF SYNCHROTRON RADIATION

Metabolic Communication between Astrocytes and Neurons via Bicarbonate-Responsive Soluble Adenylyl Cyclase

(2012) Hyun B. Choi et al.   NEURON

Regulation of Anterior Chamber Drainage by Bicarbonate-sensitive Soluble Adenylyl Cyclase in the Ciliary Body

(2011) Yong S. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular cAMP signaling by soluble adenylyl cyclase

(2011) Martin Tresguerres et al.   KIDNEY INTERNATIONAL

Inhibitors of membranous adenylyl cyclases

(2011) Roland Seifert et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Novel Inhibitors Complexed with Glutamate Dehydrogenase

(2009) Ming Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capturing adenylyl cyclases as potential drug targets

(2009) Sandra Pierre et al.   NATURE REVIEWS DRUG DISCOVERY

Structure-Based Development of Novel Adenylyl Cyclase Inhibitors

(2008) Christine Schlicker et al.   JOURNAL OF MEDICINAL CHEMISTRY