Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction

Counter-regulation of T cell effector function by differentially activated p38

(2014) Muhammad S. Alam et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells

(2014) Julio Gomez-Rodriguez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of Epidermal p38α Signaling Prevents UVR-Induced Inflammation via Acute and Chronic Mechanisms

(2014) Yasuyo Sano et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tuning of Protein Kinase Circuitry by p38α Is Vital for Epithelial Tissue Homeostasis

(2013) Celia Caballero-Franco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p38  Senses Environmental Stress To Control Innate Immune Responses via Mechanistic Target of Rapamycin

(2013) K. Katholnig et al.   JOURNAL OF IMMUNOLOGY

Cross Talk between the Akt and p38  Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

(2013) V. A. McGuire et al.   MOLECULAR AND CELLULAR BIOLOGY

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

(2012) Gonghua Huang et al.   NATURE IMMUNOLOGY

Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease

(2012) P. Ritprajak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

(2011) R. Noubade et al.   BLOOD

Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation

(2011) L. Jirmanova et al.   BLOOD

A novel cardioprotective p38-MAPK/mTOR pathway

(2011) Gonzalo Hernández et al.   EXPERIMENTAL CELL RESEARCH

The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation

(2011) Xing Chang et al.   IMMUNITY

Phosphorylation of Raptor by p38β Participates in Arsenite-induced Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation

(2011) Xiao-Nan Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic analysis of specific and redundant roles for p38  and p38  MAPKs during mouse development

(2011) I. del Barco Barrantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Effects of p38α Deletion in Myeloid Lineage and Gut Epithelia in Mouse Models of Inflammatory Bowel Disease

(2010) Motoyuki Otsuka et al.   GASTROENTEROLOGY

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo

(2010) Rachel A. Gottschalk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

T Cell Receptor-mediated Activation of p38α by Mono-phosphorylation of the Activation Loop Results in Altered Substrate Specificity

(2009) Paul R. Mittelstadt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic disruption of p38  Tyr323 phosphorylation prevents T-cell receptor-mediated p38  activation and impairs interferon-  production

(2008) L. Jirmanova et al.   BLOOD

The kinase p38α serves cell type–specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression

(2008) Chun Kim et al.   NATURE IMMUNOLOGY

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA