Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis

Control of Capsid Transformations during Reovirus Entry

(2021) Stephanie L. Gummersheimer et al.   Viruses-Basel

Interferon-Induced Transmembrane Protein 3 Blocks Fusion of Diverse Enveloped Viruses by Altering Mechanical Properties of Cell Membranes

(2021) Xiangyang Guo et al.   ACS Nano

Role of Lipid Transfer Proteins (LTPs) in the Viral Life Cycle

(2021) Kiran Avula et al.   Frontiers in Microbiology

Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons

(2020) Pavithra Aravamudhan et al.   PLoS Pathogens

Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infection

(2020) Kelly Urbanek et al.   JOURNAL OF VIROLOGY

Ins and Outs of Reovirus: Vesicular Trafficking in Viral Entry and Egress

(2020) Alexa N. Roth et al.   TRENDS IN MICROBIOLOGY

Lipid–Protein Interactions in Niemann–Pick Type C Disease: Insights from Molecular Modeling

(2019) Simon Wheeler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Annexins—Coordinators of Cholesterol Homeostasis in Endocytic Pathways

(2018) Carles Rentero et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Breach: Host Membrane Penetration and Entry by Nonenveloped Viruses

(2018) Chandra Shekhar Kumar et al.   TRENDS IN MICROBIOLOGY

Viral escape from endosomes and host detection at a glance

(2018) Jacqueline Staring et al.   JOURNAL OF CELL SCIENCE

Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial

(2017) Daniel S Ory et al.   LANCET

A CRISPR toolbox to study virus–host interactions

(2017) Andreas S. Puschnik et al.   NATURE REVIEWS MICROBIOLOGY

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease

(2017) Romain Bouziat et al.   SCIENCE

Entry of Bluetongue Virus Capsid Requires the Late Endosome-specific Lipid Lysobisphosphatidic Acid

(2016) Avnish Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipids Cooperate with the Reovirus Membrane Penetration Peptide to Facilitate Particle Uncoating

(2016) Anthony J. Snyder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion

(2016) Kai Liu et al.   JOURNAL OF CELL BIOLOGY

Distinct Entry Mechanisms for Nonenveloped and Quasi-Enveloped Hepatitis E Viruses

(2016) Xin Yin et al.   JOURNAL OF VIROLOGY

The Intracellular Cholesterol Transport Inhibitor U18666A Inhibits the Exosome-Dependent Release of Mature Hepatitis C Virus

(2016) Fabian Elgner et al.   JOURNAL OF VIROLOGY

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Discovery of a proteinaceous cellular receptor for a norovirus

(2016) R. C. Orchard et al.   SCIENCE

Fusion of Enveloped Viruses in Endosomes

(2016) Judith M. White et al.   TRAFFIC

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

(2016) Jennifer S. Spence et al.   mBio

CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

(2016) Jonas Dehairs et al.   Scientific Reports

Lipid Membranes Facilitate Conformational Changes Required for Reovirus Cell Entry

(2015) Anthony J. Snyder et al.   JOURNAL OF VIROLOGY

Cholesterol Flux Is Required for Endosomal Progression of African Swine Fever Virions during the Initial Establishment of Infection

(2015) Miguel Ángel Cuesta-Geijo et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

The role of spontaneous lipid curvature in the interaction of interfacially active peptides with membranes

(2014) Daniel Koller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Nogo Receptor NgR1 Mediates Infection by Mammalian Reovirus

(2014) Jennifer L. Konopka-Anstadt et al.   Cell Host & Microbe

Interferon-inducible Transmembrane Protein 3 (IFITM3) Restricts Reovirus Cell Entry

(2013) Amanda A. Anafu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry

(2013) D. Silva-Ayala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Impaired proteolysis underlies autophagic dysfunction in Niemann–Pick type C disease

(2012) Matthew J. Elrick et al.   HUMAN MOLECULAR GENETICS

Normalization of Cholesterol Homeostasis by 2-Hydroxypropyl-β-cyclodextrin in Neurons and Glia from Niemann-Pick C1 (NPC1)-deficient Mice

(2012) Kyle B. Peake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reovirus Uses Multiple Endocytic Pathways for Cell Entry

(2012) W. L. Schulz et al.   JOURNAL OF VIROLOGY

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

(2011) Mee Kian Poh et al.   ANTIVIRAL RESEARCH

The future is cold: cryo-preparation methods for transmission electron microscopy of cells

(2011) Ilse Hurbain et al.   BIOLOGY OF THE CELL

Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

(2011) C. L. Moyer et al.   JOURNAL OF VIROLOGY

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Cell entry of enveloped viruses

(2011) Richard K Plemper   Current Opinion in Virology

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

The use of RNAi-based screens to identify host proteins involved in viral replication

(2010) Alec J Hirsch   Future Microbiology

Niemann-Pick disease type C

(2010) Marie T Vanier   Orphanet Journal of Rare Diseases

Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

(2010) A. I. Rosenbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An N-terminal domain of adenovirus protein VI fragments membranes by inducing positive membrane curvature

(2010) Oana Maier et al.   VIROLOGY

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

(2009) Hyock Joo Kwon et al.   CELL

Requirements for the Formation of Membrane Pores by the Reovirus Myristoylated  1N Peptide

(2009) L. Zhang et al.   JOURNAL OF VIROLOGY

Virus entry by macropinocytosis

(2009) Jason Mercer et al.   NATURE CELL BIOLOGY

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

(2009) B. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation, Exposure and Penetration of Virally Encoded, Membrane-Active Polypeptides During Non-Enveloped Virus Entry

(2008) John Johnson et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Peptides released from reovirus outer capsid form membrane pores that recruit virus particles

(2008) Tijana Ivanovic et al.   EMBO JOURNAL