Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue

Targeting transcription factors by small compounds—Current strategies and future implications

(2016) Judith Hagenbuchner et al.   BIOCHEMICAL PHARMACOLOGY

Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation

(2016) Laura A. Jaenicke et al.   MOLECULAR CELL

Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation

(2015) Jian An et al.   MOLECULAR CELL

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression

(2015) Wenjian Gan et al.   MOLECULAR CELL

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing

(2015) Saravana P. Selvanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

(2014) Michelle Marques Howarth et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

(2014) David J. Elzi et al.   JOURNAL OF PROTEOME RESEARCH

The Colossus of Ubiquitylation: Decrypting a Cellular Code

(2013) Adam Williamson et al.   MOLECULAR CELL

Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma

(2012) Aleksandar Boro et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

(2012) S Sankar et al.   ONCOGENE

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

(2012) Silke Schlottmann et al.   Frontiers in Oncology

Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors

(2011) Peter C. Hollenhorst et al.   Annual Review of Biochemistry

Global Identification of Modular Cullin-RING Ligase Substrates

(2011) Michael J. Emanuele et al.   CELL

STEAP1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors

(2011) T. G. P. Grunewald et al.   MOLECULAR CANCER RESEARCH

COP1 is a tumour suppressor that causes degradation of ETS transcription factors

(2011) Alberto C. Vitari et al.   NATURE

EWS/FLI and Its Downstream Target NR0B1 Interact Directly to Modulate Transcription and Oncogenesis in Ewing's Sarcoma

(2009) M. Kinsey et al.   CANCER RESEARCH

O-GlcNAcylation is involved in the transcriptional activity of EWS-FLI1 in Ewing's sarcoma

(2009) R Bachmaier et al.   ONCOGENE

Translocation-Related Sarcomas

(2009) Fredrik Mertens et al.   SEMINARS IN ONCOLOGY

Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage

(2008) Iva V. Klevernic et al.   BIOCHEMICAL JOURNAL

EWS-FLI-1 Expression Triggers a Ewing's Sarcoma Initiation Program in Primary Human Mesenchymal Stem Cells

(2008) N. Riggi et al.   CANCER RESEARCH

Changes in Incidence and Survival of Ewing Sarcoma Patients Over the Past 3 Decades

(2008) Natia Esiashvili et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Identification of SCF Ubiquitin Ligase Substrates by Global Protein Stability Profiling

(2008) H.-C. S. Yen et al.   SCIENCE

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE