Article
Medicine, General & Internal
Ying Zhao, Ze-Yu Wang, Xue-Dong Zhang, Yao Wang, Wen-Hang Yang, Ying-Chun Xu
Summary: This study validated that common and rare bacteria and fungi can be detected by testing peptidoglycan (PGN), lipopolysaccharide (LPS), and (1,3)-Beta-D-Glucan (BDG) in the plasma. The diagnostic efficacy of PGN, LPS, and BDG was consistent with clinical diagnosis, with high sensitivity, specificity, and total coincidence rate. The positive rates and multi-marker detection approach for PGN, LPS, and BDG were significantly higher than that of blood culture. Plasma PGN, LPS, and BDG perform well in the early diagnosis of bloodstream infections caused by various pathogens.
Article
Fisheries
Bingying Xu, Gangwei Zhang, Lei Wang, Gladstone Sagada, Jinzhi Zhang, Qingjun Shao
Summary: The study found that an appropriate level of beta-1,3-glucan can improve the growth performance and feed utilization of Pacific white shrimp, as well as enhance their antioxidative capacity. The optimal supplemental level was around 0.156 g kg^(-1) based on weight gain in the results.
AQUACULTURE NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Sylwia Staczek, Agnieszka Zdybicka-Barabas, Iwona Wojda, Adrian Wiater, Pawel Mak, Piotr Suder, Krzysztof Skrzypiec, Malgorzata Cytrynska
Summary: The study found that the immune system of greater wax moth can recognize and trigger defense response to Aspergillus niger alpha-1,3-glucan. Various hemolymph proteins interacting with this glucan play important roles in the immune system, promoting the expression of defense peptides and increasing antifungal activity.
Article
Biochemistry & Molecular Biology
Raul Garcia, Kaori Itto-Nakama, Jose Manuel Rodriguez-Pena, Xiaolin Chen, Ana Belen Sanz, Alba de Lorenzo, Monica Pavon-Verges, Karen Kubo, Shinsuke Ohnuki, Cesar Nombela, Laura Popolo, Yoshikazu Ohya, Javier Arroyo
Summary: The study found that PA inhibits beta-1,3-glucan synthesis and affects other related enzymatic activities. Its mode of action involves the activation of the cell-wall integrity and high-osmolarity glycerol signaling pathways, distinguishing it from other antifungal agents.
Article
Fisheries
El-Sayed Hemdan Eissa, Ragaa A. Ahmed, Nadia A. Abd Elghany, Amal Elfeky, Saadea Saadony, Norhan H. Ahmed, Salah El-Sayed Sakr, Geraldine B. Dayrit, Charlene Princess S. Tolenada, Adlene Anne C. Atienza, Mahmoud Mabrok, Hala F. Ayoub
Summary: In this study, the potential effects of dietary supplementation with beta-1,3 glucan and fructooligosaccharides on the antioxidant activities, immunological response, and growth performance of Pacific white shrimp were investigated. The results showed that the supplementation significantly improved shrimp weight gain, feed conversion ratio, and digestive enzyme profiles. The antioxidants and immune biomarkers activities were also significantly elevated with increasing levels of beta-1,3 GF in the shrimp diet. The study recommends an optimal level of 1.5 g kg(-1) for enhancing growth performance and improving antioxidant activities, immunity, and disease resistance of the shrimp.
Article
Plant Sciences
Diego Rebaque, Irene del Hierro, Gemma Lopez, Laura Bacete, Francisco Vilaplana, Pietro Dallabernardina, Fabian Pfrengle, Lucia Jorda, Andrea Sanchez-Vallet, Rosa Perez, Frederic Brunner, Antonio Molina, Hugo Melida
Summary: The study found that MLGs are a group of carbohydrate-based molecular patterns perceived by plants, with MLG43 being the smallest structure capable of triggering strong pattern-triggered immunity responses and disease resistance. The mechanism of MLG43 recognition differs from that of other carbohydrate MAMPs, providing potential insights into plant immunity mechanisms.
Article
Immunology
Qian Meng, Pei-Pei Wu, Miao-Miao Li, Rui-Hao Shu, Gui-Ling Zhou, Ji-Hong Zhang, Huan Zhang, Haobo Jiang, Qi-Lian Qin, Zhen Zou
Summary: Melanization and encapsulation are important defense responses against microbes in host insects. In the ghost moth Thitarodes xiaojinensis, the proteins beta GRP1 and IML8 play crucial roles in modulating immune responses, while O. sinensis may evade melanization by preventing beta GRP1 recognition.
JOURNAL OF IMMUNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Junwen Ma, Zhen Qin, Peng Zhou, Ruiming Wang, Qiaojuan Yan, Zhengqiang Jiang, Shaoqing Yang
Summary: In this study, we reported the complex structures and recognition patterns of a fungal GH family 81 endo-beta-1,3-glucanase from Rhizomucor miehei (RmLam81A). Our results provide a structural basis for understanding the diverse physiological functions of beta-1,3-glucanases.
ENZYME AND MICROBIAL TECHNOLOGY
(2022)
Article
Engineering, Biomedical
Jing Wei Jin, Min Zhi Rong, Ming Qiu Zhang, Wing-Leung Wong
Summary: The water-soluble aminated beta-1,3-D-glucan (AG) showed no obvious cytotoxicity at certain concentrations and exhibited significant anti-inflammatory effects. AG/pDNA nanocomposites prepared by electrostatic interaction have appropriate particle sizes and zeta potentials, leading to significantly increased transfection efficiencies in cells.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Immunology
Wisarut Junprung, Premruethai Supungul, Nutthapon Sangklai, Anchalee Tassanakajon
Summary: Recent studies show that LvHSP70 binds to the pattern recognition receptor LvLGBP and activates the prophenoloxidase system, leading to the immune response in shrimp.
JOURNAL OF IMMUNOLOGY
(2022)
Article
Fisheries
Saengchan Senapin, Ha Thanh Dong, Watcharachai Meemetta, Akasit Siriphongphaew, Walaiporn Charoensapsri, Wanida Santimanawong, Warren A. Turner, Channarong Rodkhum, Boonsirm Withyachumnarnkul, Rapeepun Vanichviriyakit
Article
Fisheries
Pakkakul Sangsuriya, Walaiporn Charoensapsri, Sudarat Chomwong, Saengchan Senapin, Anchalee Tassanakajon, Piti Amparyup
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2016)
Article
Fisheries
H. T. Dong, C. Techatanakitarnan, P. Jindakittikul, A. Thaiprayoon, S. Taengphu, W. Charoensapsri, P. Khunrae, T. Rattanarojpong, S. Senapin
JOURNAL OF FISH DISEASES
(2017)
Article
Biochemical Research Methods
Thanunthon Bowornsakulwong, Walaiporn Charoensapsri, Triwit Rattanarojpong, Pongsak Khunrae
PROTEIN EXPRESSION AND PURIFICATION
(2017)
Article
Fisheries
Kantamas Apitanyasai, Piti Amparyup, Walaiporn Charoensapsri, Pakkakul Sangsuriya, Anchalee Tassanakajon
FISH & SHELLFISH IMMUNOLOGY
(2018)
Article
Fisheries
Sudarat Chomwong, Walaiporn Charoensapsri, Piti Amparyup, Anchalee Tassanakajon
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2018)
Article
Fisheries
Akapon Vaniksampanna, Siwaporn Longyant, Walaiporn Charoensapsri, Paisarn Sithigorngul, Parin Chaivisuthangkura
FISH & SHELLFISH IMMUNOLOGY
(2019)
Article
Fisheries
Piti Amparyup, Walaiporn Charoensapsri, Nusree Samaluka, Parichat Chumtong, Patchari Yocawibun, Chanprapa Imjongjirak
FISH & SHELLFISH IMMUNOLOGY
(2020)
Article
Fisheries
Piti Amparyup, Walaiporn Charoensapsri, Suthinee Soponpong, Miti Jearaphunt, Ratree Wongpanya, Anchalee Tassanakajon
Summary: The cytosolic DNA-sensing immune response plays a crucial role in recognizing and establishing effective host immune responses to pathogens. The discovery of the Penaeus monodon stimulator of interferon gene (PmSTING) and interferon regulatory factor (PmIRF) genes highlights their important roles in host defense against viral infections, mediating antiviral immune defenses via signaling cascade in P. monodon.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Piti Amparyup, Supakarn Sungkaew, Walaiporn Charoensapsri, Paveena Tapaneeyaworawong, Parichat Chumtong, Patchari Yocawibun, Prarthana Pantong, Ratree Wongpanya, Chanprapa Imjongjirak, Sorawit Powtongsook
Summary: In this study, we identified PUFA biosynthesis-related genes in A. royi and found that copepodid and adult stages are high in LC-PUFAs. The increased gene expression in the adult stages is correlated with the higher concentration of DHA and EPA.
AQUACULTURE REPORTS
(2022)
Article
Fisheries
Piti Amparyup, Supakarn Sungkaew, Walaiporn Charoensapsri, Parichat Chumtong, Patchari Yocawibun, Paveena Tapaneeyaworawong, Ratree Wongpanya, Chanprapa Imjongjirak
Summary: This study conducted genome sequencing and analysis of Apocyclops royi, a small aquatic crustacean. The researchers identified genes related to the shrimp Toll pathway and discovered a novel antimicrobial peptide. The expression analysis indicated the importance of these genes in the immune response of copepods. This knowledge can be applied to future functional studies and disease prevention in copepod aquaculture.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Fisheries
Thitiya Rattanadilog Na Phuket, Walaiporn Charoensapsri, Piti Amparyup, Chanprapa Imjongjirak
Summary: The crab proline-rich AMP SpPR-AMP1 has potent antimicrobial activity against both Gram-positive and Gram-negative bacteria. This study demonstrates that SpPR-AMP1 has therapeutic effects against AHPND infection caused by Vibrio campbellii VH-639 and can enhance the innate immune response in shrimp Litopenaeus vannamei. SpPR-AMP1 disrupts the bacterial cell membrane and promotes shrimp's resistance against V. campbellii VH-639 infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Kornsunee Phiwsaiya, Walaiporn Charoensapsri, Suwimon Taengphu, Ha T. Dong, Pakkakul Sangsuriya, Giang T. T. Nguyen, Hung Q. Pham, Piti Amparyup, Kallaya Sritunyalucksana, Suparat Taengchaiyaphum, Parin Chaivisuthangkura, Siwaporn Longyant, Paisarn Sithigorngul, Saengchan Senapin
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2017)
Article
Fisheries
Chanprapa Imjongjirak, Pawanrat Amphaiphan, Walaiporn Charoensapsri, Piti Amparyup
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2017)
Article
Fisheries
H. T. Dong, S. Taengphu, P. Sangsuriya, W. Charoensapsri, K. Phiwsaiya, T. Sornwatana, P. Khunrae, T. Rattanarojpong, S. Senapin
