Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes

Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans

(2015) Ming-Jiang Xu et al.   GASTROENTEROLOGY

Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis

(2015) Xu Xu et al.   HEPATOLOGY

CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis

(2015) Cédric Langhi et al.   HEPATOLOGY

Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice

(2015) Linkang Zhou et al.   Nature Communications

The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

(2015) David Barneda et al.   eLife

Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

(2014) Peter Dietrich et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Lipid droplet biogenesis

(2014) Florian Wilfling et al.   CURRENT OPINION IN CELL BIOLOGY

Rab8a-AS160-MSS4 Regulatory Circuit Controls Lipid Droplet Fusion and Growth

(2014) Lizhen Wu et al.   DEVELOPMENTAL CELL

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

(2014) Florian Wilfling et al.   eLife

FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes

(2013) Tan Hooi Min Grahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fasting regulates FSP27 expression in the liver

(2013) Vishwajeet Puri   JOURNAL OF LIPID RESEARCH

The genetic contribution of CIDEA polymorphisms, haplotypes and loci interaction to obesity in a Han Chinese population

(2013) Jingjing Wu et al.   MOLECULAR BIOLOGY REPORTS

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic Regulation of Hepatic Lipid Droplet Properties by Diet

(2013) Amanda E. Crunk et al.   PLoS One

Cidea controls lipid droplet fusion and lipid storage in brown and white adipose tissue

(2013) LiZhen Wu et al.   Science China-Life Sciences

Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

(2013) Zhiqi Sun et al.   Nature Communications

CIDE Proteins and Lipid Metabolism

(2012) Li Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Controlling the size of lipid droplets: lipid and protein factors

(2012) Hongyuan Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Cidea promotes hepatic steatosis by sensing dietary fatty acids

(2012) Linkang Zhou et al.   HEPATOLOGY

Fsp27/CIDECis a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate

(2012) Anna Vilà-Brau et al.   JOURNAL OF LIPID RESEARCH

Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation

(2012) Xuanhe Li et al.   JOURNAL OF LIPID RESEARCH

Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

(2011) Natalie Krahmer et al.   Cell Metabolism

Murine Diacylglycerol Acyltransferase-2 (DGAT2) Can Catalyze Triacylglycerol Synthesis and Promote Lipid Droplet Formation Independent of Its Localization to the Endoplasmic Reticulum

(2011) Pamela J. McFie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

Role of lipid droplet proteins in liver steatosis

(2011) Toshikatsu Okumura   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation

(2011) Srikarthika Jambunathan et al.   PLoS One

Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation

(2011) D. A. Gross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fat-specific Protein 27 Undergoes Ubiquitin-dependent Degradation Regulated by Triacylglycerol Synthesis and Lipid Droplet Formation

(2010) Zongqian Nian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Which CIDE are you on? Apoptosis and energy metabolism

(2010) Tomo Yonezawa et al.   Molecular BioSystems

Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA

(2009) Kun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid Droplets Finally Get a Little R-E-S-P-E-C-T

(2009) Robert V. Farese et al.   CELL

Cideb, an ER- and Lipid Droplet-Associated Protein, Mediates VLDL Lipidation and Maturation by Interacting with Apolipoprotein B

(2009) Jing Ye et al.   Cell Metabolism

CIDE proteins and metabolic disorders

(2009) Jingyi Gong et al.   CURRENT OPINION IN LIPIDOLOGY

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC

(2009) Oscar Rubio-Cabezas et al.   EMBO Molecular Medicine

Hepatic lipid metabolism and non-alcoholic fatty liver disease

(2009) P. Tessari et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Hepatic Expression of Cell Death–inducing DFFA-like Effector C in Obese Subjects Is Reduced by Marked Weight Loss

(2009) Angela M. Hall et al.   Obesity

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

The Metabolic Syndrome

(2008) Marc-Andre Cornier et al.   ENDOCRINE REVIEWS

Cell death–inducing DNA fragmentation factor α–like effector A (CIDEA) gene V115F (G→T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men

(2008) Ling Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Up-Regulation of Mitochondrial Activity and Acquirement of Brown Adipose Tissue-Like Property in the White Adipose Tissue of Fsp27 Deficient Mice

(2008) Shen Yon Toh et al.   PLoS One

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

(2008) G MUSSO et al.   PROGRESS IN LIPID RESEARCH