Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

Therapeutic Manipulation of Tumor-associated Macrophages: Facts and Hopes from a Clinical and Translational Perspective

(2021) Paola Allavena et al.   CLINICAL CANCER RESEARCH

Macrophage M2 Co-expression Factors Correlate With the Immune Microenvironment and Predict Outcome of Renal Clear Cell Carcinoma

(2021) Yutao Wang et al.   Frontiers in Genetics

The new biology of PTCL‐NOS and AITL: current status and future clinical impact

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Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases

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Biology and Molecular Pathogenesis of Mature T-Cell Lymphomas

(2020) José R. Cortés et al.   Cold Spring Harbor Perspectives in Medicine

VAV1 mutations contribute to development of T-cell neoplasms in mice

(2020) Kota Fukumoto et al.   BLOOD

Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

(2019) Yosaku Watatani et al.   LEUKEMIA

Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity

(2019) Joshua D. Welch et al.   CELL

Reproducing the Molecular Subclassification of Peripheral T-cell Lymphoma-NOS by Immunohistochemistry

(2019) Catalina Amador et al.   BLOOD

NicheNet: modeling intercellular communication by linking ligands to target genes

(2019) Robin Browaeys et al.   NATURE METHODS

Pathogenesis of Peripheral T Cell Lymphoma

(2018) Marco Pizzi et al.   Annual Review of Pathology-Mechanisms of Disease

RhoA G17V is sufficient to induce autoimmunity and promotes T cell lymphomagenesis in mice

(2018) Samuel Y. Ng et al.   BLOOD

RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis

(2018) Jose R. Cortes et al.   CANCER CELL

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

(2018) Leona Gabryšová et al.   NATURE IMMUNOLOGY

seq-ImmuCC: Cell-Centric View of Tissue Transcriptome Measuring Cellular Compositions of Immune Microenvironment From Mouse RNA-Seq Data

(2018) Ziyi Chen et al.   Frontiers in Immunology

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C − Cells

(2017) Alexander Mildner et al.   IMMUNITY

Activation of RHOA–VAV1 signaling in angioimmunoblastic T-cell lymphoma

(2017) M Fujisawa et al.   LEUKEMIA

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

(2017) Yu Liu et al.   NATURE GENETICS

Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas

(2017) Francesco Abate et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Elevated serum interleukin-10 level and M2 macrophage infiltration are associated with poor survival in angioimmunoblastic T-cell lymphoma

(2017) Jun Soo Ham et al.   Oncotarget

Inference of immune cell composition on the expression profiles of mouse tissue

(2017) Ziyi Chen et al.   Scientific Reports

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

(2016) R. L. Boddicker et al.   BLOOD

The 2016 revision of the World Health Organization classification of lymphoid neoplasms

(2016) S. H. Swerdlow et al.   BLOOD

The curious origins of angioimmunoblastic T-cell lymphoma

(2016) José R. Cortés et al.   CURRENT OPINION IN HEMATOLOGY

GATA3 expression correlates with poor prognosis and tumor-associated macrophage infiltration in peripheral T cell lymphoma

(2016) Wei Editor et al.   Oncotarget

Inactivating mutations in GNA13 and RHOA in Burkitt’s lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells

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GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features

(2014) T. Wang et al.   BLOOD

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

(2014) J. Iqbal et al.   BLOOD

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(2014) Teresa Palomero et al.   NATURE GENETICS

T-Cell Receptor Signaling in Peripheral T-Cell Lymphoma – A Review of Patterns of Alterations in a Central Growth Regulatory Pathway

(2013) Kathrin Warner et al.   Current Hematologic Malignancy Reports

Generation of CD4CreERT2transgenic mice to study development of peripheral CD4-T-cells

(2012) Katayoun Aghajani et al.   GENESIS

Accurate detection of the tumor clone in peripheral T-cell lymphoma biopsies by flow cytometric analysis of TCR-Vβ repertoire

(2012) Dimitri Salameire et al.   MODERN PATHOLOGY

The genetic landscape of mutations in Burkitt lymphoma

(2012) Cassandra Love et al.   NATURE GENETICS

TET2andDNMT3AMutations in Human T-Cell Lymphoma

(2012) Lucile Couronné et al.   NEW ENGLAND JOURNAL OF MEDICINE

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

(2012) J. G. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements

(2012) Aditi Kanhere et al.   Nature Communications

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

(2011) Kelly Moran-Crusio et al.   CANCER CELL

A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment

(2011) Shawn Rose et al.   CYTOMETRY PART A

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

Impaired TH2 response in patients with Vav1-deficient common variable immunodeficiency with T-cell defects

(2010) Nagaja Capitani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

(2009) Gang Wei et al.   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

International Peripheral T-Cell and Natural Killer/T-Cell Lymphoma Study: Pathology Findings and Clinical Outcomes

(2008)   JOURNAL OF CLINICAL ONCOLOGY

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology