Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication

Chromatin mechanics dictates subdiffusion and coarsening dynamics of embedded condensates

(2021) Daniel S. W. Lee et al.   Nature Physics

Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation

(2021) Olga Vladimirova et al.   PLoS Pathogens

The HSV-1 Transcription Factor ICP4 Confers Liquid-Like Properties to Viral Replication Compartments

(2021) Michael Seyffert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Learning the molecular grammar of protein condensates from sequence determinants and embeddings

(2021) Kadi L. Saar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

(2021) Jasmine Cubuk et al.   Nature Communications

Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses

(2021) Florian Geiger et al.   EMBO JOURNAL

Viral Induced Protein Aggregation: A Mechanism of Immune Evasion

(2021) Elena Muscolino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Composition-dependent thermodynamics of intracellular phase separation

(2020) Joshua A. Riback et al.   NATURE

Human cytomegalovirus IE2 drives transcription initiation from a select subset of late infection viral promoters by host RNA polymerase II

(2020) Ming Li et al.   PLoS Pathogens

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

(2020) Serafima Guseva et al.   Science Advances

Copy-Paste Mutagenesis: A Method for Large-Scale Alteration of Viral Genomes

(2019) Jiajia Tang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Mechanism of DNA-Induced Phase Separation for Transcriptional Repressor VRN1

(2019) Huabin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA

(2019) Anastasia S. Singatulina et al.   Cell Reports

Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation

(2019) David Trombley McSwiggen et al.   eLife

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

(2019) Marta Alenquer et al.   Nature Communications

Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles

(2019) Yuqin Zhou et al.   JOURNAL OF VIROLOGY

Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences

(2019) David T. McSwiggen et al.   GENES & DEVELOPMENT

The liquid nucleome – phase transitions in the nucleus at a glance

(2019) Amy R. Strom et al.   JOURNAL OF CELL SCIENCE

Herpesviruses induce aggregation and selective autophagy of host signalling proteins NEMO and RIPK1 as an immune-evasion mechanism

(2019) Elena Muscolino et al.   Nature Microbiology

DNA-induced liquid phase condensation of cGAS activates innate immune signaling

(2018) Mingjian Du et al.   SCIENCE

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

(2018) Won-Ki Cho et al.   SCIENCE

Paraspeckles: Where Long Noncoding RNA Meets Phase Separation

(2018) Archa H. Fox et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

(2018) Bianca S. Heinrich et al.   mBio

Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome

(2018) Yongdae Shin et al.   CELL

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

(2018) Dan Bracha et al.   CELL

Differential Requirement of Human Cytomegalovirus UL112-113 Protein Isoforms for Viral Replication

(2017) Tim Schommartz et al.   JOURNAL OF VIROLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Negri bodies are viral factories with properties of liquid organelles

(2017) Jovan Nikolic et al.   Nature Communications

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis

(2016) Tim Schommartz et al.   JOURNAL OF VIROLOGY

Emerging Role of PML Nuclear Bodies in Innate Immune Signaling

(2016) Myriam Scherer et al.   JOURNAL OF VIROLOGY

Gene Expression Correlates with the Number of Herpes Viral Genomes Initiating Infection in Single Cells

(2016) Efrat M. Cohen et al.   PLoS Pathogens

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

UL84-independent replication of human cytomegalovirus strains conferred by a single codon change in UL122

(2015) David J. Spector   VIROLOGY

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Viral and cellular subnuclear structures in human cytomegalovirus-infected cells

(2014) B. L. Strang   JOURNAL OF GENERAL VIROLOGY

The pathogenesis of human cytomegalovirus

(2014) Paul Griffiths et al.   JOURNAL OF PATHOLOGY

Dynamic and Nucleolin-Dependent Localization of Human Cytomegalovirus UL84 to the Periphery of Viral Replication Compartments and Nucleoli

(2014) B. J. Bender et al.   JOURNAL OF VIROLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Analysis of the interactions of viral and cellular factors with human cytomegalovirus lytic origin of replication, oriLyt

(2012) Dominique Kagele et al.   VIROLOGY

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

The Carboxy-Terminal Segment of the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 Is Crucial for Viral Replication

(2010) L. A. Silva et al.   JOURNAL OF VIROLOGY

Role of the Specific Interaction of UL112-113 p84 with UL44 DNA Polymerase Processivity Factor in Promoting DNA Replication of Human Cytomegalovirus

(2010) Y.-E. Kim et al.   JOURNAL OF VIROLOGY

Herpesviruses carrying a Brainbow cassette reveal replication and expression of limited numbers of incoming genomes

(2010) Oren Kobiler et al.   Nature Communications

The Human Cytomegalovirus UL112-113 Locus Can Activate the Full Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Cycle

(2009) R. Wells et al.   JOURNAL OF VIROLOGY

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E

(2008) C. Sinzger et al.   JOURNAL OF GENERAL VIROLOGY