miR-4324 inhibits ovarian cancer progression by targeting FEN1

miR‑140‑5p inhibits cervical cancer cell phenotypes via downregulating FEN1 to halt the cell cycle

(2020) Yanrong Guo et al.   Molecular Medicine Reports

FEN1 mediates miR-200a methylation and promotes breast cancer cell growth via MET and EGFR signaling

(2019) Xue Zeng et al.   FASEB JOURNAL

Downregulation of microRNA-4324 promotes the EMT of esophageal squamous-cell carcinoma cells via upregulating FAK

(2019) Jian Zhou et al.   OncoTargets and Therapy

TGFβ1- miR-140-5p axis mediated up-regulation of Flap Endonuclease 1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

(2019) Chuanfei Li et al.   Aging-US

Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1

(2019) Hong Zhu et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNA-140 impedes DNA repair by targeting FEN1 and enhances chemotherapeutic response in breast cancer

(2019) Xiao Lu et al.   ONCOGENE

MiR‐195 and miR‐497 suppress tumorigenesis in lung cancer by inhibiting SMURF2‐induced TGF‐β receptor I ubiquitination

(2019) Dong‐Kyu Chae et al.   Molecular Oncology

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

(2018) Keqiang Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Up-regulation of miR-383-5p suppresses proliferation and enhances chemosensitivity in ovarian cancer cells by targeting TRIM27

(2018) Jing Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladder cancer

(2018) Qiangqiang Ge et al.   INTERNATIONAL JOURNAL OF CANCER

Structural basis of 5′ flap recognition and protein–protein interactions of human flap endonuclease 1

(2018) Hong Xu et al.   NUCLEIC ACIDS RESEARCH

miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells

(2015) Xue-tao Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

(2014) KEJIA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

(2014) Tarek M.A. Abdel-Fatah et al.   Molecular Oncology

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

(2012) Amy E. Pasquinelli   NATURE REVIEWS GENETICS