MiR‐195 and miR‐497 suppress tumorigenesis in lung cancer by inhibiting SMURF2‐induced TGF‐β receptor I ubiquitination

E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer

(2019) Fee Klupp et al.   Cancer Management and Research

Identification of miR-195-3p as an oncogene in RCC

(2017) Lu Jin et al.   Molecular Medicine Reports

The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis

(2017) Xiang Chen et al.   Scientific Reports

LPA Gene Polymorphisms and Gene Expression Associated with Coronary Artery Disease

(2017) Zi-Kai Song et al.   Biomed Research International

microRNA-497 Modulates Breast Cancer Cell Proliferation, Invasion, and Survival by Targeting SMAD7

(2016) Jingjing Liu et al.   DNA AND CELL BIOLOGY

Experimental evidences for hsa-miR-497-5p as a negative regulator of SMAD3 gene expression

(2016) Meisam Jafarzadeh et al.   GENE

Role of miR-497 in VEGF-A-mediated cancer cell growth and invasion in non-small cell lung cancer

(2016) Aiqin Gu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TGF-β1 regulating miR-205/miR-195 expression affects the TGF-β signal pathway by respectively targeting SMAD2/SMAD7

(2016) Yingjun Duan et al.   ONCOLOGY REPORTS

Diagnostic and prognostic value of plasma microRNA-195 in patients with non-small cell lung cancer

(2016) Keli Su et al.   World Journal of Surgical Oncology

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

(2015) A S Chandhoke et al.   CELL DEATH AND DIFFERENTIATION

miR-15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer

(2015) WEN-LONG ZHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1)

(2015) Zhiyuan Han et al.   Oncotarget

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis

(2015) Jianwei Xu et al.   Oncotarget

Two Faces of TGF-Beta1 in Breast Cancer

(2014) Joanna Magdalena Zarzynska   MEDIATORS OF INFLAMMATION

Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis

(2014) Shan Cao et al.   MOLECULAR BIOLOGY OF THE CELL

miR-195 inhibits the growth and metastasis of NSCLC cells by targeting IGF1R

(2014) Xiaoli Wang et al.   TUMOR BIOLOGY

miR-195 Targets HDGF to inhibit proliferation and invasion of NSCLC cells

(2014) Haizhou Guo et al.   TUMOR BIOLOGY

Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner

(2014) Diana David et al.   Cell Division

Downregulation of miR-497 promotes tumor growth and angiogenesis by targeting HDGF in non-small cell lung cancer

(2013) Wen-yan Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma

(2013) Mayuko Furuta et al.   PLoS One

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

(2012) Long Zhang et al.   NATURE CELL BIOLOGY

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

(2012) Michael Blank et al.   NATURE MEDICINE

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

Crosstalk between TGF-β signaling and the microRNA machinery

(2012) Henriett Butz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of TGF-β receptor activity

(2012) Fei Huang et al.   Cell and Bioscience

Analysis of MiR-195 and MiR-497 Expression, Regulation and Role in Breast Cancer

(2011) D. Li et al.   CLINICAL CANCER RESEARCH

miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2

(2011) Wei Zhu et al.   MEDICAL ONCOLOGY

MicroRNA: Biogenesis, Function and Role in Cancer

(2010) Leigh-Ann MacFarlane et al.   CURRENT GENOMICS

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

(2010) Guo-Kun Wang et al.   EUROPEAN HEART JOURNAL

Smad Ubiquitylation Regulatory Factor 1/2 (Smurf1/2) Promotes p53 Degradation by Stabilizing the E3 Ligase MDM2

(2010) Jing Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and Invasiveness

(2009) C. Jin et al.   CANCER RESEARCH

Pin1 Down-regulates Transforming Growth Factor-β (TGF-β) Signaling by Inducing Degradation of Smad Proteins

(2009) Ayako Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice

(2008) Qiuqian Wu et al.   ARTHRITIS AND RHEUMATISM

Caveolin-1, transforming growth factor-β receptor internalization, and the pathogenesis of systemic sclerosis

(2008) Francesco Del Galdo et al.   CURRENT OPINION IN RHEUMATOLOGY

Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma

(2008) Richard J Flavin et al.   MODERN PATHOLOGY