Improvement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

(2015) Natasha Zamudio et al.   GENES & DEVELOPMENT

Impact of sperm DNA chromatin in the clinic

(2015) Dimitrios Ioannou et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Hydrogen sulfide protects testicular germ cells against heat-induced injury

(2015) Guang Li et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies

(2015) Mancheng Gong et al.   PLoS One

Role of genetic mutations in folate-related enzyme genes on Male Infertility

(2015) Kang Liu et al.   Scientific Reports

Germline Methylation Patterns Determine the Distribution of Recombination Events in the Dog Genome

(2014) Jonas Berglund et al.   Genome Biology and Evolution

Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of theMTHFR677C>T (c.665C>T) Variant

(2014) Danielle N. Meadows et al.   HUMAN MUTATION

Unmetabolized Folic Acid Is Detected in Nearly All Serum Samples from US Children, Adolescents, and Adults

(2014) Christine M Pfeiffer et al.   JOURNAL OF NUTRITION

Oxidative Stress Induces Persistent Telomeric DNA Damage Responsible for Nuclear Morphology Change in Mammalian Cells

(2014) Elisa Coluzzi et al.   PLoS One

Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase byS-adenosylmethionine

(2014) June Ereño-Orbea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The importance of the one carbon cycle nutritional support in human male fertility: a preliminary clinical report

(2014) Maurizio Dattilo et al.   Reproductive Biology and Endocrinology

DNA Methylation in Mammals

(2014) E. Li et al.   Cold Spring Harbor Perspectives in Biology

Histone hyperacetylation during meiosis interferes with large-scale chromatin remodeling, axial chromatid condensation and sister chromatid separation in the mammalian oocyte

(2013) Feikun Yang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Zinc Absorption by Young Adults from Supplemental Zinc Citrate Is Comparable with That from Zinc Gluconate and Higher than from Zinc Oxide

(2013) Rita Wegmüller et al.   JOURNAL OF NUTRITION

The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment

(2013) Sheena E.M. Lewis et al.   REPRODUCTIVE BIOMEDICINE ONLINE

MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults

(2012) Xianhui Qin et al.   Nutrition Journal

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Association of the Methylenetetrahydrofolate Reductase Gene A1298C Polymorphism with Male Infertility: A Meta-Analysis

(2011) Ouxi Shen et al.   ANNALS OF HUMAN GENETICS

The role of antioxidant therapy in the treatment of male infertility: an overview

(2011) Francesco Lombardo et al.   ASIAN JOURNAL OF ANDROLOGY

Meiotic recombination and male infertility: from basic science to clinical reality?

(2011) Michael C Hann et al.   ASIAN JOURNAL OF ANDROLOGY

Poly(ADP-Ribose) Polymerases PARP1 and PARP2 Modulate Topoisomerase II Beta (TOP2B) Function During Chromatin Condensation in Mouse Spermiogenesis1

(2011) Mirella L. Meyer-Ficca et al.   BIOLOGY OF REPRODUCTION

Mathematical Modeling Predicts the Effect of Folate Deficiency and Excess on Cancer-Related Biomarkers

(2011) M. L. Neuhouser et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Divergent effects of the 677C>T mutation of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene on ovarian responsiveness and anti-Müllerian hormone concentrations

(2011) Roman Pavlik et al.   FERTILITY AND STERILITY

The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy

(2011) P. Gharagozloo et al.   HUMAN REPRODUCTION

Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism

(2011) Ruma Banerjee   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic polymorphisms of the enzymes involved in DNA methylation and synthesis in elite athletes

(2011) Ileana Terruzzi et al.   PHYSIOLOGICAL GENOMICS

Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy

(2011) Nathan R. Treff et al.   PLoS Genetics

Deletion of murine choline dehydrogenase results in diminished sperm motility

(2010) Amy R. Johnson et al.   FASEB JOURNAL

Transgenerational epigenetic inheritance: More questions than answers

(2010) L. Daxinger et al.   GENOME RESEARCH

Protamine contents and P1/P2 ratio in human spermatozoa from smokers and non-smokers

(2010) M. Hammadeh et al.   HUMAN REPRODUCTION

A liquid chromatography–tandem mass spectrometric method for quantitative determination of native 5-methyltetrahydrofolate and its polyglutamyl derivatives in raw vegetables

(2010) Chao Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

DNA damage and repair in human oocytes and embryos: a review

(2010) Yves Ménézo et al.   ZYGOTE

Persistent circulating unmetabolised folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification?

(2009) Mary R Sweeney et al.   BMC PUBLIC HEALTH

Variations in folate pathway genes are associated with unexplained female infertility

(2009) Signe Altmäe et al.   FERTILITY AND STERILITY

Folate Content in Tomato (Lycopersicon esculentum). Influence of Cultivar, Ripeness, Year of Harvest, and Pasteurization and Storage Temperatures

(2009) M. Dolores Iniesta et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Function of sperm chromatin structural elements in fertilization and development

(2009) W. S. Ward   MOLECULAR HUMAN REPRODUCTION

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human genetic selection on the MTHFR 677C>T polymorphism

(2008) Álvaro Mayor-Olea et al.   BMC Medical Genetics

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE