Characterization of a Cryptic NRPS Gene Cluster in Bacillus velezensis FZB42 Reveals a Discrete Oxidase Involved in Multithiazole Biosynthesis

Branched Chain Lipid Metabolism As a Determinant of the N-Acyl Variation of Streptomyces Natural Products

(2021) Neil P. J. Price et al.   ACS Chemical Biology

Genomics-Driven Activation of Silent Biosynthetic Gene Clusters in Burkholderia gladioli by Screening Recombineering System

(2021) Hanna Chen et al.   MOLECULES

Establishment of recombineering genome editing system in Paraburkholderia megapolitana empowers activation of silent biosynthetic gene clusters

(2020) Wentao Zheng et al.   Microbial Biotechnology

Investigation of Indigoidine Synthetase Reveals a Conserved Active-Site Base Residue of Nonribosomal Peptide Synthetase Oxidases

(2020) Bo Pang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison

(2019) Dmitry Ghilarov et al.   MOLECULAR CELL

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi

(2019) Yohei Morishita et al.   ORGANIC LETTERS

Genome mining and prospects for antibiotic discovery

(2019) Lucy Foulston   CURRENT OPINION IN MICROBIOLOGY

Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species

(2018) Tawatchai Thongkongkaew et al.   ACS Chemical Biology

Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome

(2018) Eric J. N. Helfrich et al.   Nature Microbiology

Novel Methoxymethacrylate Natural Products Uncovered by Statistics-Based Mining of the Myxococcus fulvus Secondary Metabolome

(2018) Fabian Panter et al.   ACS Chemical Biology

ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes

(2017) Hailong Wang et al.   NUCLEIC ACIDS RESEARCH

RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles

(2017) Adrian L. Pietkiewicz et al.   ACS Medicinal Chemistry Letters

Swarming motility plays the major role in migration during tomato root colonization by Bacillus subtilis SWR01

(2016) Shengfeng Gao et al.   BIOLOGICAL CONTROL

Bacillus velezensis is not a later heterotypic synonym of Bacillus amyloliquefaciens; Bacillus methylotrophicus, Bacillus amyloliquefaciens subsp. plantarum and ‘Bacillus oryzicola’ are later heterotypic synonyms of Bacillus velezensis based on phylogenomics

(2016) Christopher A. Dunlap et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Engineering microbial hosts for production of bacterial natural products

(2016) Mingzi M. Zhang et al.   NATURAL PRODUCT REPORTS

Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster in Bacillus subtilis via Red/ET recombineering

(2016) Qingshu Liu et al.   Scientific Reports

Unusual non-enzymatic flavin catalysis enhances understanding of flavoenzymes

(2015) Erick A. Argueta et al.   FEBS LETTERS

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

High-Titer Heterologous Production in E. coli of Lyngbyatoxin, a Protein Kinase C Activator from an Uncultured Marine Cyanobacterium

(2013) Sarah E. Ongley et al.   ACS Chemical Biology

Flavoprotein oxidases: classification and applications

(2013) Willem P. Dijkman et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases

(2013) Joel O. Melby et al.   BIOCHEMISTRY

Direct Cloning, Genetic Engineering, and Heterologous Expression of the Syringolin Biosynthetic Gene Cluster inE. colithrough Red/ET Recombineering

(2012) Xiaoying Bian et al.   CHEMBIOCHEM

Marthiapeptide A, an Anti-infective and Cytotoxic Polythiazole Cyclopeptide from a 60 L Scale Fermentation of the Deep Sea-Derived Marinactinospora thermotolerans SCSIO 00652

(2012) Xiao Zhou et al.   JOURNAL OF NATURAL PRODUCTS

Identification and Characterization of the Echinocandin B Biosynthetic Gene Cluster from Emericella rugulosa NRRL 11440

(2012) Ralph A. Cacho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting

(2012) Jun Fu et al.   NATURE BIOTECHNOLOGY

A structure–activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity

(2012) Seong Jong Kim et al.   MedChemComm

Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates

(2011) Joel O Melby et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Comparative Analysis of the Biosynthetic Gene Clusters and Pathways for Three Structurally Related Antitumor Antibiotics: Bleomycin, Tallysomycin, and Zorbamycin

(2011) Ute Galm et al.   JOURNAL OF NATURAL PRODUCTS

Structural Basis of the Antiproliferative Activity of Largazole, a Depsipeptide Inhibitor of the Histone Deacetylases

(2011) Kathryn E. Cole et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tracking Flavin Conformations in Protein Crystal Structures with Raman Spectroscopy and QM/MM Calculations

(2010) Åsmund Kjendseth Røhr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

(2009) John A. McIntosh et al.   NATURAL PRODUCT REPORTS

Role of DptE and DptF in the lipidation reaction of daptomycin

(2008) Melanie Wittmann et al.   FEBS Journal

Genome analysis of Bacillus amyloliquefaciens FZB42 reveals its potential for biocontrol of plant pathogens

(2008) X.H. Chen et al.   JOURNAL OF BIOTECHNOLOGY

More than Anticipated – Production of Antibiotics and Other Secondary Metabolites by Bacillus amyloliquefaciens FZB42

(2008) Xiao-Hua Chen et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Morphing peptide backbones into heterocycles

(2008) C. T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA