Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-05-19
DOI
10.1038/s41467-022-30387-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD
- (2021) Alexander Schmitz et al. Frontiers in Cellular Neuroscience
- Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide
- (2021) Hélène Tran et al. NATURE MEDICINE
- A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
- (2021) Yoshifumi Sonobe et al. Nature Communications
- The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
- (2020) Yevgeniya A. Abramzon et al. Frontiers in Neuroscience
- CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration
- (2020) Gopinath Krishnan et al. ACTA NEUROPATHOLOGICA
- Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS
- (2020) Katherine D. LaClair et al. ACTA NEUROPATHOLOGICA
- Antisense Drugs Make Sense for Neurological Diseases
- (2020) C. Frank Bennett et al. Annual Review of Pharmacology and Toxicology
- C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo
- (2019) So Yoen Choi et al. NATURE NEUROSCIENCE
- Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development
- (2019) Sonia M. Vallabh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells
- (2019) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers
- (2019) Alexander J. Cammack et al. NEUROLOGY
- Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model
- (2019) Lien Nguyen et al. NEURON
- Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers
- (2018) Lieke H.H. Meeter et al. Annals of Clinical and Translational Neurology
- Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease
- (2018) Nobutaka Sakae et al. Acta Neuropathologica Communications
- C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
- (2017) Youn-Bok Lee et al. HUMAN MOLECULAR GENETICS
- Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72 -associated amyotrophic lateral sclerosis
- (2017) Tania F. Gendron et al. Science Translational Medicine
- There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS
- (2016) Aaron D. Gitler et al. BRAIN RESEARCH
- C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
- (2016) Yong-Jie Zhang et al. NATURE NEUROSCIENCE
- Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons
- (2016) Rodrigo Lopez-Gonzalez et al. NEURON
- Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers
- (2015) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers
- (2015) Ian R. A. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72
- (2015) Marka van Blitterswijk et al. ACTA NEUROPATHOLOGICA
- Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
- (2015) Martin H. Schludi et al. ACTA NEUROPATHOLOGICA
- Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
- (2014) Yong-Jie Zhang et al. ACTA NEUROPATHOLOGICA
- C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
- (2014) Stephanie May et al. ACTA NEUROPATHOLOGICA
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now