Ketogenic diet inhibits tumor growth by enhancing immune response, attenuating immunosuppression, inhibiting angiogenesis and EMT in CT26 colon tumor allografts mouse model

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

(2021) Xiaoming Dai et al.   MOLECULAR CELL

A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood donors independent of age and sex

(2020) Susanne Axelsson et al.   BMC IMMUNOLOGY

Regulation of sister chromatid cohesion by nuclear PD-L1

(2020) Jia Yu et al.   CELL RESEARCH

CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p

(2020) Jinjin Lai et al.   Cancer Cell International

Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer

(2020) Yehui Shi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A ketogenic diet elicits anti-tumor properties through inducing oxidative stress, inhibiting MMP-9 expression and rebalancing M1/M2 tumor-associated macrophages phenotype in a mouse model of colon cancer

(2020) Ning Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches

(2020) Rezan Güler et al.   Scientific Reports

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

(2020) Gladys Ferrere et al.   JCI Insight

Transient increase of activated regulatory T cells early after kidney transplantation

(2019) Young-Seon Mederacke et al.   Scientific Reports

Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL

(2019) Yeong-Jin Kim et al.   Cancer Cell International

Ketogenic diet in the treatment of cancer – Where do we stand?

(2019) Daniela D. Weber et al.   Molecular Metabolism

Ketogenic diet combined with antioxidant N-acetylcysteine inhibits tumor growth in a mouse model of anaplastic thyroid cancer

(2019) Abha Aggarwal et al.   SURGERY

Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer

(2019) E Fiegle et al.   NEOPLASIA

Down Regulation of c-FLIPL Enhance PD-1 Blockade Efficacy in B16 Melanoma

(2019) Yao Wang et al.   Frontiers in Oncology

Structure-based derivation and intramolecular cyclization of peptide inhibitors from PD-1/PD-L1 complex interface as immune checkpoint blockade for breast cancer immunotherapy

(2019) Kun Zhou et al.   BIOPHYSICAL CHEMISTRY

The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications

(2019) Xiaomeng Liu et al.   Molecular Cancer

Basophil-derived IL-4 promotes epicutaneous antigen sensitization concomitant with the development of food allergy

(2018) Maryam Hussain et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation

(2018) Difeng Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR2/4 ligand-amplified liver inflammation promotes initiation of autoimmune hepatitis due to sustained IL-6/IL-12/IL-4/IL-25 expression

(2018) Gang Chi et al.   MOLECULAR IMMUNOLOGY

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa

(2018) Kabir A. Khan et al.   Nature Reviews Clinical Oncology

Development of Search Strategy for Peptide Inhibitors of Immune Checkpoints

(2018) S. V. Podlesnykh et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Surgical trauma-induced CCL18 promotes recruitment of regulatory T cells and colon cancer progression

(2018) Zhirong Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics

(2017) Priti S. Hegde et al.   SEMINARS IN CANCER BIOLOGY

MicroRNA-105 is involved in TNF-α-related tumor microenvironment enhanced colorectal cancer progression

(2017) Zetao Shen et al.   Cell Death & Disease

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

(2017) Takuro Noguchi et al.   Cancer Immunology Research

Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet

(2016) Danielle M. Lussier et al.   BMC CANCER

Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases

(2016) Ileana S. Mauldin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells

(2016) Yi Huo et al.   Oncotarget

Regulation of the p53 response and its relationship to cancer

(2015) David W. Meek   BIOCHEMICAL JOURNAL

The prognostic role of the epithelial-mesenchymal transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma

(2015) Rocco Cappellesso et al.   HISTOPATHOLOGY

Network Effect of Wt-mutant p53 Interactions and Implications on p53 Gene Therapy

(2014) Xiaona Ji et al.   CURRENT PHARMACEUTICAL DESIGN

Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer

(2013) M. Sznol et al.   CLINICAL CANCER RESEARCH

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma

(2012) Mohammed G. Abdelwahab et al.   PLoS One

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

(2011) Marie Tosolini et al.   CANCER RESEARCH

Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review

(2010) Katsuhiko Nosho et al.   JOURNAL OF PATHOLOGY

Bax is upregulated by p53 signal pathway in the SPE B-induced apoptosis

(2010) Wei-Ting Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

A novel anti-cancer effect of genistein: reversal of epithelial mesenchymal transition in prostate cancer cells1

(2008) Lin-lin ZHANG et al.   ACTA PHARMACOLOGICA SINICA

The role of signal transducers and activators of transcription in colon cancer

(2007) Lidija Klampfer   Frontiers in Bioscience-Landmark