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Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

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The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction

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Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer

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AMPK: Sensing Glucose as well as Cellular Energy Status

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Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

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Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy

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The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance

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Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer

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Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study

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Identification of CMTM6 and CMTM4 as PD-L1 protein regulators

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Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

(2017) Jinfang Zhang et al.   NATURE

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

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AMPK: guardian of metabolism and mitochondrial homeostasis

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Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet

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Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

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Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity

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Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

(2016) Jonathan M. Pitt et al.   IMMUNITY

Obesity and Cancer Mechanisms: Cancer Metabolism

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Proteogenomics connects somatic mutations to signalling in breast cancer

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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

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PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

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Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet

(2015) Nicholas Douris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer

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Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies

(2015) G. Zadra et al.   MOLECULAR CANCER RESEARCH

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

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(2015) P. Sharma et al.   SCIENCE

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

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Phosphorylation of Angiomotin by Lats1/2 Kinases Inhibits F-actin Binding, Cell Migration, and Angiogenesis

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Inhibition of AMPK Catabolic Action by GSK3

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(2013) Bing Xiao et al.   Nature Communications

Obesity, Energy Balance, and Cancer: New Opportunities for Prevention

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Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response

(2012) Petra Beli et al.   MOLECULAR CELL

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

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Suppression of AMPK Activation via S485 Phosphorylation by IGF-I during Hyperglycemia Is Mediated by AKT Activation in Vascular Smooth Muscle Cells

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The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway

(2011) Sharon S. McDaniel et al.   EPILEPSIA

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

A Perspective on Cancer Cell Metastasis

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Diabetes and Cancer: A Consensus Report

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Calorie restriction and cancer prevention: metabolic and molecular mechanisms

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AMP-activated protein kinase activator A-769662 is an inhibitor of the Na+-K+-ATPase

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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism

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