ProBDNF and Brain-Derived Neurotrophic Factor Prodomain Differently Modulate Acetylcholine Release in Regenerating and Mature Mouse Motor Synapses

Therapeutic potential of targeting G protein-gated inwardly rectifying potassium (GIRK) channels in the central nervous system

(2021) Danko Jeremic et al.   PHARMACOLOGY & THERAPEUTICS

In vivo functions of p75NTR: challenges and opportunities for an emerging therapeutic target

(2021) Subash C. Malik et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

BDNF signaling in context: From synaptic regulation to psychiatric disorders

(2021) Camille S. Wang et al.   CELL

Enhanced pro-BDNF-p75NTR pathway activity in denervated skeletal muscle

(2021) Katherine Aby et al.   LIFE SCIENCES

Metabotropic Modulation of Potassium Channels During Synaptic Plasticity

(2020) D. Fernández-Fernández et al.   NEUROSCIENCE

Interaction between Calcium Chelators and the Activity of P2X7 Receptors in Mouse Motor Synapses

(2020) Anna Miteva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Histamine H3 Receptor Activation Modulates Glutamate Release in the Corticostriatal Synapse by Acting at CaV2.1 (P/Q-Type) Calcium Channels and GIRK (KIR3) Potassium Channels

(2020) Héctor Vázquez-Vázquez et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases

(2020) Mingyue Wang et al.   BRAIN RESEARCH BULLETIN

BDNF pro-peptide: physiological mechanisms and implications for depression

(2019) Masami Kojima et al.   CELL AND TISSUE RESEARCH

Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity

(2019) Ana Paula De Vincenti et al.   Frontiers in Cellular Neuroscience

Regulation of Acetylcholine Quantal Release by Coupled Thrombin/BDNF Signaling in Mouse Motor Synapses

(2019) Alexander Gaydukov et al.   Cells

Role of A1 receptor-activated GIRK channels in the suppression of hippocampal seizure activity

(2019) Emily Hill et al.   NEUROPHARMACOLOGY

Mechanism of P2X7 receptor-dependent enhancement of neuromuscular transmission in pannexin 1 knockout mice

(2018) Anna S. Miteva et al.   Purinergic Signalling

Growth factors and hormones pro-peptides: the unexpected adventures of the BDNF prodomain

(2017) Juan Pablo Zanin et al.   JOURNAL OF NEUROCHEMISTRY

PROneurotrophins and CONSequences

(2017) Rui O. Costa et al.   MOLECULAR NEUROBIOLOGY

Neuronal plasticity and neurotrophic factors in drug responses

(2017) E Castrén et al.   MOLECULAR PSYCHIATRY

Trk Receptors and Neurotrophin Cross-Interactions: New Perspectives Toward Manipulating Therapeutic Side-Effects

(2017) Yazan Haddad et al.   Frontiers in Molecular Neuroscience

Presynaptic Membrane Receptors Modulate ACh Release, Axonal Competition and Synapse Elimination during Neuromuscular Junction Development

(2017) Josep Tomàs et al.   Frontiers in Molecular Neuroscience

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

(2017) Erica Hurtado et al.   Frontiers in Molecular Neuroscience

G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity

(2017) Linda M. May et al.   Frontiers in Neuroscience

P2Y 13 receptors mediate presynaptic inhibition of acetylcholine release induced by adenine nucleotides at the mouse neuromuscular junction

(2016) Juan F. Guarracino et al.   NEUROSCIENCE

Calcitonin gene-related peptide increases acetylcholine quantal size in neuromuscular junctions of mice

(2016) Alexander E. Gaydukov et al.   NEUROSCIENCE LETTERS

Neurobiological actions by three distinct subtypes of brain-derived neurotrophic factor: Multi-ligand model of growth factor signaling

(2016) Toshiyuki Mizui et al.   PHARMACOLOGICAL RESEARCH

A1 adenosine receptor-mediated GIRK channels contribute to the resting conductance of CA1 neurons in the dorsal hippocampus

(2015) Chung Sub Kim et al.   JOURNAL OF NEUROPHYSIOLOGY

G-protein-coupled inward rectifier potassium channels involved in corticostriatal presynaptic modulation

(2015) David Meneses et al.   SYNAPSE

Dynamic Nature of the p75 Neurotrophin Receptor in Response to Injury and Disease

(2014) Rick Meeker et al.   Journal of Neuroimmune Pharmacology

Pro-Brain-Derived Neurotrophic Factor Inhibits GABAergic Neurotransmission by Activating Endocytosis and Repression of GABAA Receptors

(2014) B. Riffault et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling

(2014) Cristy Phillips et al.   Frontiers in Cellular Neuroscience

Multidirectional Effects of Calmodulin Kinase II on Transmitter Release in Mature and Newly Formed Mouse Motor Synapses

(2013) P. O. Bogatcheva et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

ProBDNF and Mature BDNF as Punishment and Reward Signals for Synapse Elimination at Mouse Neuromuscular Junctions

(2013) H. S. Je et al.   JOURNAL OF NEUROSCIENCE

Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity

(2013) Natália Assaife-Lopes et al.   Purinergic Signalling

Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction

(2013) Agustin Anastasia et al.   Nature Communications

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons

(2012) Sandra Dieni et al.   JOURNAL OF CELL BIOLOGY

Nerve injury increases brain-derived neurotrophic factor levels to suppress BK channel activity in primary sensory neurons

(2012) Xue-Hong Cao et al.   JOURNAL OF NEUROCHEMISTRY

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury

(2012) Galina Dvoriantchikova et al.   PLoS One

Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses

(2012) H. S. Je et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus

(2011) H. Mizoguchi et al.   JOURNAL OF NEUROSCIENCE

Blocking p75NTR receptors alters polyinnervationz of neuromuscular synapses during development

(2011) Neus Garcia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Adenosine drives recycled vesicles to a slow-release pool at the mouse neuromuscular junction

(2010) Paula P. Perissinotti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Localization of brain-derived neurotrophic factor, neurotrophin-4, tropomyosin-related kinase b receptor, and p75NTRreceptor by high-resolution immunohistochemistry on the adult mouse neuromuscular junction

(2010) Neus Garcia et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles

(2010) Hiroshi Hibino et al.   PHYSIOLOGICAL REVIEWS

Facilitation of Acetylcholine Secretion in Mouse Motor Synapses Caused by Calcium Release from Depots upon Activation of L-Type Calcium Channels

(2009) A. E. Gaydukov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Pro-BDNF–induced synaptic depression and retraction at developing neuromuscular synapses

(2009) Feng Yang et al.   JOURNAL OF CELL BIOLOGY

Involvement of brain-derived neurotrophic factor (BDNF) in the functional elimination of synaptic contacts at polyinnervated neuromuscular synapses during development

(2009) N. Garcia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Control of extracellular cleavage of ProBDNF by high frequency neuronal activity

(2009) G. Nagappan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival

(2009) Hisatsugu Koshimizu et al.   Molecular Brain

Activation of pro-BDNF by the pericellular serine protease plasmin

(2008) Kelly Gray et al.   FEBS LETTERS

Adenosine A1receptors inhibit GABAergic transmission in rat tuberomammillary nucleus neurons

(2008) Do-Seop Yum et al.   JOURNAL OF NEUROCHEMISTRY

p75 Neurotrophin Receptor Mediates Neuronal Cell Death by Activating GIRK Channels through Phosphatidylinositol 4,5-Bisphosphate

(2008) E. J. Coulson et al.   JOURNAL OF NEUROSCIENCE

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

(2008) Tomoya Matsumoto et al.   NATURE NEUROSCIENCE