Dynamic Nature of the p75 Neurotrophin Receptor in Response to Injury and Disease

Nerve Growth Factor Modulation of Retinal Ganglion Cell Physiology

(2014) Gloria Roberti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neurotrophin Strategies for Neuroprotection: Are They Sufficient?

(2014) Joseph P. Steiner et al.   Journal of Neuroimmune Pharmacology

Peripheral Nerve Injury Modulates Neurotrophin Signaling in the Peripheral and Central Nervous System

(2014) Mette Richner et al.   MOLECULAR NEUROBIOLOGY

Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition

(2013) Heather D. VanGuilder Starkey et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Oral Administration of a Small Molecule Targeted to Block proNGF Binding to p75 Promotes Myelin Sparing and Functional Recovery after Spinal Cord Injury

(2013) C. Tep et al.   JOURNAL OF NEUROSCIENCE

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

proNGF inhibits proliferation and oligodendrogenesis of postnatal hippocampal neural stem/progenitor cells through p75NTR in vitro

(2013) Jingjing Guo et al.   Stem Cell Research

A small molecule p75NTRligand protects neurogenesis after traumatic brain injury

(2013) Jian Shi et al.   STEM CELLS

Novel small molecule activators of the Trk family of receptor tyrosine kinases

(2012) Obiamaka Obianyo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Distribution of P75 neurotrophin receptor in adult human cochlea—an immunohistochemical study

(2012) Wei Liu et al.   CELL AND TISSUE RESEARCH

Proliferating Immature Schwann Cells Contribute to Nerve Regeneration After Ischemic Peripheral Nerve Injury

(2012) Masaki Kobayashi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced Seizures

(2012) A. P. Le et al.   JOURNAL OF NEUROSCIENCE

Nerve growth factor: from the early discoveries to the potential clinical use

(2012) Luigi Aloe et al.   Journal of Translational Medicine

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

(2012) Ying Sun et al.   PLoS One

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

(2012) Carlos F. Ibáñez et al.   TRENDS IN NEUROSCIENCES

Sortilin: a receptor to regulate neuronal viability and function

(2012) Anders Nykjaer et al.   TRENDS IN NEUROSCIENCES

Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity

(2012) D Scarpi et al.   Cell Death & Disease

Nerve growth factor: A key local regulator in the pathogenesis of inflammatory arthritis

(2011) Siba P. Raychaudhuri et al.   ARTHRITIS AND RHEUMATISM

Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?

(2011) Sune Skeldal et al.   BIOESSAYS

Targeting the Nogo Receptor Complex in Diseases of the Central Nervous System

(2011) C. L. McDonald et al.   CURRENT MEDICINAL CHEMISTRY

p75NTR Regulates A  Deposition by Increasing A  Production But Inhibiting A  Aggregation with Its Extracellular Domain

(2011) Y.-J. Wang et al.   JOURNAL OF NEUROSCIENCE

Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection

(2011) Ann B. Ragin et al.   JOURNAL OF NEUROVIROLOGY

The neurotrophin receptor p75NTR is induced on mature myofibres in inflammatory myopathies and promotes myotube survival to inflammatory stress

(2011) E. Colombo et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac

(2011) K. Deinhardt et al.   Science Signaling

Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury

(2010) T. K. Ali et al.   DIABETOLOGIA

Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons

(2010) K. Michaelsen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

p75 Neurotrophin Receptor-mediated Apoptosis in Sympathetic Neurons Involves a Biphasic Activation of JNK and Up-regulation of Tumor Necrosis Factor-α-converting Enzyme/ADAM17

(2010) Rajappa S. Kenchappa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling

(2010) C. Ceni et al.   JOURNAL OF CELL SCIENCE

ProNGF mediates death of Natural Killer cells through activation of the p75NTR–sortilin complex

(2010) Mary-Louise Rogers et al.   JOURNAL OF NEUROIMMUNOLOGY

Localization of brain-derived neurotrophic factor, neurotrophin-4, tropomyosin-related kinase b receptor, and p75NTRreceptor by high-resolution immunohistochemistry on the adult mouse neuromuscular junction

(2010) Neus Garcia et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

(2010) Christian B Vaegter et al.   NATURE NEUROSCIENCE

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease

(2010) Elliott J. Mufson et al.   NEUROSCIENCE LETTERS

Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats

(2010) Alvin V. Terry et al.   PHYSIOLOGY & BEHAVIOR

Mouse Natural Killer (NK) Cells Express the Nerve Growth Factor Receptor TrkA, which Is Dynamically Regulated

(2010) Natacha Ralainirina et al.   PLoS One

ProNGF induces TNFα-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway

(2010) Frédéric Lebrun-Julien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proNGF-p75NTR-Sortilin Signalling Complex as New Target for the Therapeutic Treatment of Parkinsons Disease

(2009) L. Chen et al.   CNS & Neurological Disorders-Drug Targets

Nerve growth factor attenuates proliferation of astrocytes via the p75 neurotrophin receptor

(2009) Andrea B. Cragnolini et al.   GLIA

A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

(2009) E. Perlson et al.   JOURNAL OF NEUROSCIENCE

The p75 Neurotrophin Receptor Promotes Amyloid- (1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo

(2009) J. K. Knowles et al.   JOURNAL OF NEUROSCIENCE

Neuronal release of proBDNF

(2009) Jianmin Yang et al.   NATURE NEUROSCIENCE

p75 reduces  -amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model

(2009) T. G. Bengoechea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Fractionation of Signaling Endosomes Containing Different Receptors

(2009) Gretchen McCaffrey et al.   TRAFFIC

Up-regulation of pro-nerve growth factor, neurotrophin receptor p75, and sortilin is associated with retrovirus-induced spongiform encephalomyelopathy

(2008) George Stoica et al.   BRAIN RESEARCH

Pan-neurotrophin receptor p75NTR expression is strongly induced in lesional atopic mast cells

(2008) T. C. Fischer et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors

(2008) Stephen Skaper   CNS & Neurological Disorders-Drug Targets

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

(2008) Raya Al-Shawi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats

(2008) Yong-jun Fan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

(2008) Elliott J Mufson et al.   Expert Review of Neurotherapeutics

BDNF and its receptors in human myasthenic thymus: Implications for cell fate in thymic pathology

(2008) Angela Berzi et al.   JOURNAL OF NEUROIMMUNOLOGY

Induction of Proneurotrophins and Activation of p75NTR-Mediated Apoptosis via Neurotrophin Receptor-Interacting Factor in Hippocampal Neurons after Seizures

(2008) M. Volosin et al.   JOURNAL OF NEUROSCIENCE

Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

(2008) L. Ulmann et al.   JOURNAL OF NEUROSCIENCE

Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

(2008) Areechun Sotthibundhu et al.   NEUROBIOLOGY OF AGING

Identification and kainic acid-induced up-regulation of low-affinity p75 neurotrophin receptor (p75NTR) in the nigral dopamine neurons of adult rats

(2008) Yan-Qin Wang et al.   NEUROCHEMISTRY INTERNATIONAL

Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants

(2008) Sarah E. James et al.   NEUROTOXICOLOGY

Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

(2008) Tao Yang et al.   PLoS One

The function of p75NTR in glia

(2008) Andrea B. Cragnolini et al.   TRENDS IN NEUROSCIENCES

The p75 neurotrophin receptor

(2007) Clare K. Underwood et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY