Systems toxicology of chemically induced liver and kidney injuries: histopathology-associated gene co-expression modules

Temporal Changes in Rat Liver Gene Expression after Acute Cadmium and Chromium Exposure

(2015) Michael S. Madejczyk et al.   PLoS One

Effects of Valproic Acid and Dexamethasone Administration on Early Bio-Markers and Gene Expression Profile in Acute Kidney Ischemia-Reperfusion Injury in the Rat

(2015) Ryan W. Speir et al.   PLoS One

Systems Toxicology: From Basic Research to Risk Assessment

(2014) Shana J. Sturla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Open TG-GATEs: a large-scale toxicogenomics database

(2014) Yoshinobu Igarashi et al.   NUCLEIC ACIDS RESEARCH

Characterization of Chemically Induced Liver Injuries Using Gene Co-Expression Modules

(2014) Gregory J. Tawa et al.   PLoS One

Systems Level Analysis and Identification of Pathways and Networks Associated with Liver Fibrosis

(2014) Mohamed Diwan M. AbdulHameed et al.   PLoS One

Calponin Expression in Renal Tubulointerstitial Fibrosis Induced in Rats by Cisplatin

(2014) Takahiro Yuasa et al.   Journal of Toxicologic Pathology

Whole adult organism transcriptional profiling of acute metal exposures in male Zebrafish

(2014) Naissan Hussainzada et al.   BMC Pharmacology & Toxicology

Triamterene Crystalline Nephropathy

(2013) Samih H. Nasr et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Drug-Induced Liver Injury: Mechanisms, Types and Biomarkers

(2013) M. Vinken et al.   CURRENT MEDICINAL CHEMISTRY

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

(2013) M. Iskar et al.   Molecular Systems Biology

Exposure to Cobalt Causes Transcriptomic and Proteomic Changes in Two Rat Liver Derived Cell Lines

(2013) Matthew G. Permenter et al.   PLoS One

A reversible model for periportal fibrosis and a refined alternative to bile duct ligation

(2013) Philip M. E. Probert et al.   Toxicology Research

Systems Pharmacology to Predict Drug Toxicity: Integration Across Levels of Biological Organization

(2012) Jane P.F. Bai et al.   Annual Review of Pharmacology and Toxicology

The impact of network biology in pharmacology and toxicology

(2012) G. Panagiotou et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats

(2011) Marie-Noële Chobert et al.   LABORATORY INVESTIGATION

Biomarkers of liver fibrosis

(2010) Leon A Adams   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

(2010) Frank Dieterle et al.   NATURE BIOTECHNOLOGY

The Comparative Toxicogenomics Database: update 2011

(2010) A. P. Davis et al.   NUCLEIC ACIDS RESEARCH

Independent filtering increases detection power for high-throughput experiments

(2010) R. Bourgon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomics: Applications in mechanism elucidation

(2009) Venita Gresham et al.   ADVANCED DRUG DELIVERY REVIEWS

Attenuation of N-nitrosodiethylamine-induced liver fibrosis by high-molecular-weight fucoidan derived fromCladosiphon okamuranus

(2009) Kyoumi Nakazato et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Application of connectivity mapping in predictive toxicology based on gene-expression similarity

(2009) Joshua L. Smalley et al.   TOXICOLOGY

arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

(2008) Audrey Kauffmann et al.   BIOINFORMATICS

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development

(2008) Eric A.G. Blomme et al.   TOXICOLOGY LETTERS