Article
Chemistry, Multidisciplinary
Haixian Ren, Fangjun Huo, Caixia Yin
Summary: Hypochlorous acid, with low physiological concentration, is crucial in killing pathogens and has anti-inflammatory properties in the human immune system. Sensitively detecting tiny concentration changes of HOCl is necessary for understanding inflammation-associated diseases and cancer. The probe JBD effectively detects endogenous hypochlorous acid and provides insights into its role in oxidative stress and immune responses.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Spectroscopy
Xiong Chen, Detao Jiang, Chen Jiang, Cheng Yao
Summary: In this study, phenothiazine was chosen as a fluorophore to construct a NIR fluorescent probe PMM for monitoring the level of hypochlorous acid (HOCl) in lysosomes. PMM is a colorimetric and ratiometric fluorescent probe with high sensitivity, low detection limit, high selectivity, and anti-interference. It has been successfully used for fluorescence imaging of exogenous and endogenous HOCl in HepG2 cells, as well as in vivo detection in nude mice.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Feng Ding, Han Wen, Ruijiang Zhuo, Jiawei Li, Hui Zheng, Yuru Deng, Jianliang Shen, Xiaojun He
Summary: This study presents a novel chemosensor CMTH based on coumarin for highly sensitive and selective detection of HClO in various organisms, with ultrafast response time and good water solubility being its key features.
ANALYTICA CHIMICA ACTA
(2021)
Article
Spectroscopy
Youming Shen, Xiangyang Zhang, Chunxiang Zhang, Yucai Tang
Summary: HClO and H2S play various roles in biological organisms, and the redox balance between them is closely related to physiological and pathological processes. Therefore, developing a reversible ratiometric fluorescent probe for monitoring the redox process between HClO and H2S is of great significance.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Huimin Shangguan, Qianwei Liu, Yuanjuan Wang, Zixuan Teng, Rumeng Tian, Tong Wu, Lei Yang, Ling Jiang, Xingjiang Liu, Liuhe Wei
Summary: In this study, a chromenoquinoline-based ratiometric fluorescent probe was developed for the detection and quantification of hypochlorous acid (HClO). The probe exhibited a large Stokes shift, high synthetic yield, simple synthesis method, short response time, low detection limit, and low toxicity. The probe was successfully validated in live cells and zebrafish.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Wangbo Qu, Taiyu Guo, Bin Yang, Ruowei Tian, Shuang Qiu, Xinyue Chen, Zhirong Geng, Zhilin Wang
Summary: DFSN is a fluorescent probe with AIE and ESIPT, which can efficiently track hypochlorous acid in vivo. The probe has good selectivity and sensitivity, and can detect hypochlorous acid with the naked eye.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Aishan Zheng, Han Liu, Chuanhao Peng, Xiaonan Gao, Kehua Xu, Bo Tang
Summary: CVS is a mitochondria-targeting near-Infrared fluorescent probe designed for sensing and detecting HOCl with high selectivity and low detection limit. It has been successfully applied to image HOCl in mitochondria of HepG2 cells, providing a perspective method for further study of physiological and pathological functions related to HOCl.
Article
Chemistry, Analytical
Yi-Qing Sun, Yue Cheng, Xue-Bo Yin
Summary: By utilizing a dual-ligand strategy and metal-organic framework technology, high sensitivity, visual detection, and rapid response for hypochlorous acid were achieved, providing a new method for HClO detection.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Manoj Kumar Goshisht, Neetu Tripathi, Goutam Kumar Patra, Manohar Chaskar
Summary: Biological species, such as ROS, RSS, RNS, F-, Pd2+, Cu2+, Hg2+, play vital roles in cellular functions but their abnormal concentrations can lead to serious diseases. Monitoring these species in cellular organelles is crucial. Ratiometric fluorescent probes have gained attention as a potential solution, offering increased sensitivity by measuring intensity changes in two emission bands caused by the analyte. This review article discusses publications (2015-2022) on organelle-targeting ratiometric fluorescent probes, including strategies, mechanisms, scope, and challenges.
Article
Chemistry, Applied
Guangshuai Zhou, Shaobo Hou, Ning Zhao, Nathaniel Finney, Yali Wang
Summary: A highly sensitive ratiometric fluorescent probe, NAP-RS, was designed for measuring fluctuations of lysosomal HOCl. The probe exhibited a clear fluorescence response to HOCl at biologically-relevant concentrations, with rapid response time and ultrasensitivity. Additionally, it could be used for visualizing exogenous and endogenous lysosomal HOCl.
Article
Spectroscopy
Yaqian Li, Yi Zhou, Xiu Liu, Jieni Lei, Xin Qin, Guangyi Li, Zi Yang
Summary: In this paper, a near-infrared ratiometric fluorescent probe (YQ-1) was developed to detect hypochlorous acid (HClO) for comprehending its biological functions within cells. YQ-1 exhibited a fluorescence shift from red to green with a large blue shift (165 nm) in the presence of HClO, and the solution's color changed from pink to yellow. YQ-1 quickly detected HClO (within 40 s) with a low detection limit (4.47 x 10-7 mol/L) and was not affected by other interferences.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Shaohui Han, Hong Wang, Haipu Li, Ke Li, Jianxiu Wang, Xiangzhi Song
Summary: Intracellular redox homeostasis is crucial for living organisms, but real-time monitoring of this process is challenging. This article presents a dual-functional, reversible, and ratiometric fluorescent probe designed to monitor the redox state between ClO- and GSH. The probe shows good performance and can be used for imaging the dynamic redox state in acute lung injury progression.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yuanqiang Hao, Yintang Zhang, Qiuling Sun, Shu Chen, Zilong Tang, Rongjin Zeng, Maotian Xu
Summary: Hypochlorous acid (HOCl) is a potent reactive oxygen species essential in biological processes. A new ratiometric fluorescent probe has been designed and synthesized for sensitive and selective detection of HOCl, with advantages including rapid response, high signal to noise ratio, and utility for visualizing HOCl in cells and organisms.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Hui Dong, Le Zhao, Tao Wang, Yanan Chen, Wanqing Hao, Ziyi Zhang, Yizhao Hao, Cunliang Zhang, Xiuhua Wei, Yintang Zhang, Yanli Zhou, Maotian Xu
Summary: In this study, a dual-mode sensor based on a single probe (Re-BChE) was developed for accurate detection of biomarkers in blood. The sensor demonstrated high sensitivity and low detection limit for BChE using both electrochemical and fluorescence methods. The dual-mode readout of the sensor can correct errors and achieve more accurate results.
ANALYTICAL CHEMISTRY
(2023)
Article
Spectroscopy
Biao Gu, Mengqin Liu, Jiumei Long, Xinrong Ye, Zhifeng Xu, Youming Shen
Summary: In this contribution, a novel AIE-based fluorescent chemosensor has been developed for the rapid and accurate detection of intracellular hypochlorous acid (HClO). The probe demonstrates high sensitivity and selectivity towards HClO and is capable of imaging exogenous and endogenous HClO in living cells through dual channels. This research has potential applications in the biological and environmental fields.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)