Activity levels of cathepsins B and L in tumor cells are a biomarker for efficacy of reovirus-mediated tumor cell killing

The Nogo Receptor NgR1 Mediates Infection by Mammalian Reovirus

(2014) Jennifer L. Konopka-Anstadt et al.   Cell Host & Microbe

Phase 1 Clinical Trial of Intratumoral Reovirus Infusion for the Treatment of Recurrent Malignant Gliomas in Adults

(2014) Kimberly P Kicielinski et al.   MOLECULAR THERAPY

Oncolytic Reovirus in Canine Mast Cell Tumor

(2013) Chung Chew Hwang et al.   PLoS One

Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer

(2013) J S Carew et al.   Cell Death & Disease

TGF-β Signaling, Activated Stromal Fibroblasts, and Cysteine Cathepsins B and L Drive the Invasive Growth of Human Melanoma Cells

(2012) Miao Yin et al.   AMERICAN JOURNAL OF PATHOLOGY

Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

(2012) Katie Twigger et al.   BMC CANCER

Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies

(2012) E. M. Karapanagiotou et al.   CLINICAL CANCER RESEARCH

TRAIL and Noxa Are Selectively Upregulated in Prostate Cancer Cells Downstream of the RIG-I/MAVS Signaling Pathway by Nonreplicating Sendai Virus Particles

(2012) T. Matsushima-Miyagi et al.   CLINICAL CANCER RESEARCH

Recent Clinical Experience with Oncolytic Viruses

(2012) O. G. Donnelly et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Reovirus: A Targeted Therapeutic--Progress And Potential

(2012) R. Maitra et al.   MOLECULAR CANCER RESEARCH

Phase II Trial of Intravenous Administration of Reolysin® (Reovirus Serotype-3-dearing Strain) in Patients with Metastatic Melanoma

(2012) Evanthia Galanis et al.   MOLECULAR THERAPY

Procathepsin L secretion, which triggers tumour progression, is regulated by Rab4a in human melanoma cells

(2011) Alice Barbarin et al.   BIOCHEMICAL JOURNAL

Apoptosis Induced by Mammalian Reovirus Is Beta Interferon (IFN) Independent and Enhanced by IFN Regulatory Factor 3- and NF- B-Dependent Expression of Noxa

(2011) J. J. Knowlton et al.   JOURNAL OF VIROLOGY

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction and augments bortezomib-mediated apoptosis in multiple myeloma

(2011) K R Kelly et al.   ONCOGENE

Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection

(2011) Shaun Rosebeck et al.   VIROLOGY

Susceptibility of mantle cell lymphomas to reovirus oncolysis

(2009) Tommy Alain et al.   LEUKEMIA RESEARCH

Transient infection of freshly isolated human colorectal tumor cells by reovirus T3D intermediate subviral particles

(2008) W J van Houdt et al.   CANCER GENE THERAPY

Reovirus infection of cancer cells is not due to activated Ras pathway

(2008) L Song et al.   CANCER GENE THERAPY