Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis

(2018) Mark Trinder et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis

(2018) Kelly Roveran Genga et al.   Scientific Reports

Two-year follow-up of patients with septic shock presenting with low HDL: the effect upon acute kidney injury, death and estimated glomerular filtration rate

(2017) K. Roveran Genga et al.   JOURNAL OF INTERNAL MEDICINE

High-Density Lipoproteins: Nature’s Multifunctional Nanoparticles

(2016) Rui Kuai et al.   ACS Nano

Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity

(2016) Carolyne K Smith et al.   ANNALS OF THE RHEUMATIC DISEASES

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Influence of route of administration and lipidation of apolipoprotein A-I peptide on pharmacokinetics and cholesterol mobilization

(2016) Jie Tang et al.   JOURNAL OF LIPID RESEARCH

The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties

(2015) Anna Schwendeman et al.   JOURNAL OF LIPID RESEARCH

HDL in sepsis – risk factor and therapeutic approach

(2015) Emily E. Morin et al.   Frontiers in Pharmacology

Apolipoprotein A-I mimetic peptide 4F attenuates kidney injury, heart injury, and endothelial dysfunction in sepsis

(2014) Roberto S. Moreira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Strategies to improve drug development for sepsis

(2014) Mitchell P. Fink et al.   NATURE REVIEWS DRUG DISCOVERY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

High Density Lipoprotein Protects against Polymicrobe-induced Sepsis in Mice

(2013) Ling Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Martini Force Field Parameters for Glycolipids

(2013) César A. López et al.   Journal of Chemical Theory and Computation

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

(2013) Dominic De Nardo et al.   NATURE IMMUNOLOGY

Gender differences in sepsis

(2013) Martin K Angele et al.   Virulence

HDL and ApoA-I inhibit antigen presentation-mediated T cell activation by disrupting lipid rafts in antigen presenting cells

(2012) Shu-hui Wang et al.   ATHEROSCLEROSIS

The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins

(2011) Belinda A. Di Bartolo et al.   ATHEROSCLEROSIS

g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates

(2010) Jochen S. Hub et al.   Journal of Chemical Theory and Computation

ATP binding cassette G1-dependent cholesterol efflux during inflammation

(2010) Maria C. de Beer et al.   JOURNAL OF LIPID RESEARCH

Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol

(2010) Xuewei Zhu et al.   JOURNAL OF LIPID RESEARCH

The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats

(2010) Lijun Dai et al.   JOURNAL OF LIPID RESEARCH

Sepsis and Endothelial Permeability

(2010) Warren L. Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apolipoprotein A-I mimetic peptide treatment inhibits inflammatory responses and improves survival in septic rats

(2009) Zhenghao Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Apolipoprotein A-I inhibits chemotaxis, adhesion, activation of THP-1 cells and improves the plasma HDL inflammatory index

(2009) Li Wang et al.   CYTOKINE

Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

(2009) Ling Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Martini Coarse-Grained Force Field: Extension to Carbohydrates

(2009) Cesar A. López et al.   Journal of Chemical Theory and Computation

Low serum concentration of apolipoprotein A-I is an indicator of poor prognosis in cirrhotic patients with severe sepsis

(2009) Ming-Hung Tsai et al.   JOURNAL OF HEPATOLOGY

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

The metabolism and anti-atherogenic properties of HDL

(2008) Kerry-Anne Rye et al.   JOURNAL OF LIPID RESEARCH