Understanding the combined effects of multiple stressors: A new perspective on a longstanding challenge

REVIEW Assessing North Atlantic right whale health: threats, and development of tools critical for conservation of the species

(2021) MJ Moore et al.   DISEASES OF AQUATIC ORGANISMS

Classifying human influences on terrestrial ecosystems

(2021) Matthias C. Rillig et al.   GLOBAL CHANGE BIOLOGY

The Temporal Dynamics of Multiple Stressor Effects: From Individuals to Ecosystems

(2021) Michelle C. Jackson et al.   TRENDS IN ECOLOGY & EVOLUTION

A guide to state–space modeling of ecological time series

(2021) Marie Auger‐Méthé et al.   ECOLOGICAL MONOGRAPHS

Predicting consequences of POP-induced disruption of blubber glucose uptake, mass gain rate and thyroid hormone levels for weaning mass in grey seal pups

(2021) Kimberley A. Bennett et al.   ENVIRONMENT INTERNATIONAL

Refocusing multiple stressor research around the targets and scales of ecological impacts

(2021) Benno I. Simmons et al.   Nature Ecology & Evolution

Towards a unified study of multiple stressors: divisions and common goals across research disciplines

(2020) James A. Orr et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reproduction in a polluted world: implications for wildlife

(2020) Lucinda C Aulsebrook et al.   REPRODUCTION

Ecological impacts of human‐induced animal behaviour change

(2020) Margaret W. Wilson et al.   ECOLOGY LETTERS

Using a newly introduced framework to measure ecological stressor interactions

(2020) Elif Tekin et al.   ECOLOGY LETTERS

Statistical Implementations of Agent‐Based Demographic Models

(2020) Mevin Hooten et al.   INTERNATIONAL STATISTICAL REVIEW

Thresholds for ecological responses to global change do not emerge from empirical data

(2020) Helmut Hillebrand et al.   Nature Ecology & Evolution

A review of the combined effects of climate change and other local human stressors on the marine environment

(2020) Elena Gissi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Should We Care If Models Are Phenomenological or Mechanistic?

(2019) Craig R. White et al.   TRENDS IN ECOLOGY & EVOLUTION

Gross and histopathologic diagnoses from North Atlantic right whale Eubalaena glacialis mortalities between 2003 and 2018

(2019) SM Sharp et al.   DISEASES OF AQUATIC ORGANISMS

Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures

(2019) Antonio F. Hernandez et al.   ARCHIVES OF TOXICOLOGY

Climate Change, Human Impacts, and Coastal Ecosystems in the Anthropocene

(2019) Qiang He et al.   CURRENT BIOLOGY

Predicting the ecological status of rivers and streams under different climatic and socioeconomic scenarios using Bayesian Belief Networks

(2019) Eugenio Molina-Navarro et al.   LIMNOLOGICA

When things don't add up: quantifying impacts of multiple stressors from individual metabolism to ecosystem processing

(2018) Nika Galic et al.   ECOLOGY LETTERS

Predicting the effects of polychlorinated biphenyls on cetacean populations through impacts on immunity and calf survival

(2018) Ailsa J. Hall et al.   ENVIRONMENTAL POLLUTION

Vulnerability of the global terrestrial ecosystems to climate change

(2018) Delong Li et al.   GLOBAL CHANGE BIOLOGY

Advancing understanding and prediction in multiple stressor research through a mechanistic basis for null models

(2018) Ralf B. Schäfer et al.   GLOBAL CHANGE BIOLOGY

Experimental strategies to assess the biological ramifications of multiple drivers of global ocean change-A review

(2018) Philip W. Boyd et al.   GLOBAL CHANGE BIOLOGY

Direct and indirect effects of multiple stressors on stream invertebrates across watershed, reach and site scales: A structural equation modelling better informing on hydromorphological impacts

(2018) B. Villeneuve et al.   SCIENCE OF THE TOTAL ENVIRONMENT

To replicate, or not to replicate - that is the question: how to tackle nonlinear responses in ecological experiments

(2018) Juergen Kreyling et al.   ECOLOGY LETTERS

Multiple-stressor effects on freshwater fish: Importance of taxonomy and life stage

(2018) Katharina Lange et al.   FISH AND FISHERIES

Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments

(2018) Elaine A. Cohen Hubal et al.   Journal of Exposure Science and Environmental Epidemiology

Understanding the population consequences of disturbance

(2018) Enrico Pirotta et al.   Ecology and Evolution

Using the Value of Information to improve conservation decision making

(2018) Friederike C. Bolam et al.   BIOLOGICAL REVIEWS

Effects of three global change drivers on terrestrial C:N:P stoichiometry: a global synthesis

(2017) Kai Yue et al.   GLOBAL CHANGE BIOLOGY

Embracing uncertainty in applied ecology

(2017) E. J. Milner-Gulland et al.   JOURNAL OF APPLIED ECOLOGY

Determining the behavioural dose–response relationship of marine mammals to air gun noise and source proximity

(2017) Rebecca A. Dunlop et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Body condition changes arising from natural factors and fishing gear entanglements in North Atlantic right whales Eubalaena glacialis

(2017) HM Pettis et al.   Endangered Species Research

Fecal glucocorticoids and anthropogenic injury and mortality in North Atlantic right whales Eubalaena glacialis

(2017) RM Rolland et al.   Endangered Species Research

Slow recovery of Barataria Bay dolphin health following the Deepwater Horizon oil spill (2013-2014), with evidence of persistent lung disease and impaired stress response

(2017) CR Smith et al.   Endangered Species Research

Co-existence of multiple trade-off currencies shapes evolutionary outcomes

(2017) Alan A. Cohen et al.   PLoS One

Multiple Stressors in a Changing World: The Need for an Improved Perspective on Physiological Responses to the Dynamic Marine Environment

(2016) Alex R. Gunderson et al.   Annual Review of Marine Science

Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop

(2016) Kyla W. Taylor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Health of North Atlantic right whales Eubalaena glacialis over three decades: from individual health to demographic and population health trends

(2016) RM Rolland et al.   MARINE ECOLOGY PROGRESS SERIES

Rethinking our approach to multiple stressor studies in marine environments

(2016) BD Griffen et al.   MARINE ECOLOGY PROGRESS SERIES

Persistent pollutants, persistent threats

(2016) P. D. Jepson et al.   SCIENCE

Entanglement is a costly life-history stage in large whales

(2016) Julie van der Hoop et al.   Ecology and Evolution

Health of North Atlantic right whales Eubalaena glacialis over three decades: from individual health to demographic and population health trends

(2016) RM Rolland et al.   MARINE ECOLOGY PROGRESS SERIES

Rethinking our approach to multiple stressor studies in marine environments

(2016) BD Griffen et al.   MARINE ECOLOGY PROGRESS SERIES

Determinants of uncertainty in wildlife responses to human disturbance

(2015) Zulima Tablado et al.   BIOLOGICAL REVIEWS

Net effects of multiple stressors in freshwater ecosystems: a meta-analysis

(2015) Michelle C. Jackson et al.   GLOBAL CHANGE BIOLOGY

A review and meta-analysis of the effects of multiple abiotic stressors on marine embryos and larvae

(2015) Rachel Przeslawski et al.   GLOBAL CHANGE BIOLOGY

Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds

(2015) Vanessa Delfosse et al.   Nature Communications

Spatial and temporal changes in cumulative human impacts on the world’s ocean

(2015) Benjamin S. Halpern et al.   Nature Communications

Reconceptualizing synergism and antagonism among multiple stressors

(2015) Jeremy J. Piggott et al.   Ecology and Evolution

Policymakers’ and Scientists’ Ranks of Research Priorities for Resource-Management Policy

(2014) Murray A. Rudd et al.   BIOSCIENCE

Mapping Change in Human Pressure Globally on Land and within Protected Areas

(2014) JONAS GELDMANN et al.   CONSERVATION BIOLOGY

Assessing the Impact of Multiple Stressors on Aquatic Biota: The Receptor’s Side Matters

(2014) H. Segner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Dose-response relationships for the onset of avoidance of sonar by free-ranging killer whales

(2014) Patrick J. O. Miller et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Embracing thresholds for better environmental management

(2014) R. P. Kelly et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantifying Synergy: A Systematic Review of Mixture Toxicity Studies within Environmental Toxicology

(2014) Nina Cedergreen   PLoS One

Shape constrained additive models

(2014) Natalya Pya et al.   STATISTICS AND COMPUTING

Conservation physiology across scales: insights from the marine realm

(2014) S. J. Cooke et al.   Conservation Physiology

Identifying non-independent anthropogenic risks using a behavioral individual-based model

(2013) C.A.D. Semeniuk et al.   Ecological Complexity

Quantifying effects of abiotic and biotic drivers on community dynamics with multivariate autoregressive (MAR) models

(2013) Stephanie E. Hampton et al.   ECOLOGY

Unraveling the Health Effects of Environmental Mixtures: An NIEHS Priority

(2013) Danielle J. Carlin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Interactive short-term effects of equivalent temperature and air pollution on human mortality in Berlin and Lisbon

(2013) Katrin Burkart et al.   ENVIRONMENTAL POLLUTION

Simplifying complexity: Mixture toxicity assessment in the last 20 years

(2013) Rolf Altenburger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Evidence for multiple stressor interactions and effects on coral reefs

(2013) Stephen S. Ban et al.   GLOBAL CHANGE BIOLOGY

Managing for Interactions between Local and Global Stressors of Ecosystems

(2013) Christopher J. Brown et al.   PLoS One

Meta-analysis reveals complex marine biological responses to the interactive effects of ocean acidification and warming

(2013) Ben P. Harvey et al.   Ecology and Evolution

Predicting Interactions among Fishing, Ocean Warming, and Ocean Acidification in a Marine System with Whole-Ecosystem Models

(2012) Gary P. Griffith et al.   CONSERVATION BIOLOGY

Interactions between chemical and climate stressors: A role for mechanistic toxicology in assessing climate change risks

(2012) Michael J. Hooper et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

How do aquatic communities respond to contaminants? It depends on the ecological context

(2012) William H. Clements et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Simple additive effects are rare: a quantitative review of plant biomass and soil process responses to combined manipulations of CO2and temperature

(2012) Wouter I. J. Dieleman et al.   GLOBAL CHANGE BIOLOGY

Disrupting the effects of synergies between stressors: improved water quality dampens the effects of future CO2on a marine habitat

(2012) Laura J. Falkenberg et al.   JOURNAL OF APPLIED ECOLOGY

Integrating dynamic energy budget (DEB) theory with traditional bioenergetic models

(2012) R. M. Nisbet et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Energetic requirements of North Atlantic right whales and the implications for species recovery

(2012) SME Fortune et al.   MARINE ECOLOGY PROGRESS SERIES

The Anthropocene: From Global Change to Planetary Stewardship

(2011) Will Steffen et al.   AMBIO

Lethal entanglement in baleen whales

(2011) RM Cassoff et al.   DISEASES OF AQUATIC ORGANISMS

Response of Mytilus galloprovincialis (L.) to increasing seawater temperature and to marteliosis: Metabolic and physiological parameters

(2010) Andreas Anestis et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Multiple stressors in freshwater ecosystems

(2010) S. J. ORMEROD et al.   FRESHWATER BIOLOGY

Climate change predicted to cause severe increase of organic carbon in lakes

(2010) SØREN LARSEN et al.   GLOBAL CHANGE BIOLOGY

Passive and active adaptive management: Approaches and an example

(2010) Byron K. Williams   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Generalized concentration addition: A method for examining mixtures containing partial agonists

(2009) Gregory J. Howard et al.   JOURNAL OF THEORETICAL BIOLOGY

Movement, dive behavior, and survival of California sea lions (Zalophus californianus) posttreatment for domoic acid toxicosis

(2009) Kate Thomas et al.   MARINE MAMMAL SCIENCE

Irreversible climate change due to carbon dioxide emissions

(2009) Susan Solomon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between effects of environmental chemicals and natural stressors: A review

(2009) Martin Holmstrup et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Adaptive monitoring: a new paradigm for long-term research and monitoring

(2009) David B. Lindenmayer et al.   TRENDS IN ECOLOGY & EVOLUTION

Integrated Ecosystem Assessments: Developing the Scientific Basis for Ecosystem-Based Management of the Ocean

(2009) Phillip S Levin et al.   PLOS BIOLOGY

A multi-model framework for simulating wildlife population response to land-use and climate change

(2008) Brad H. McRae et al.   ECOLOGICAL MODELLING

UNDERSTANDING AND PREDICTING ECOLOGICAL DYNAMICS: ARE MAJOR SURPRISES INEVITABLE

(2008) Daniel F. Doak et al.   ECOLOGY

Quantifying the evidence for ecological synergies

(2008) Emily S. Darling et al.   ECOLOGY LETTERS

Interactive and cumulative effects of multiple human stressors in marine systems

(2008) Caitlin Mullan Crain et al.   ECOLOGY LETTERS

The Hill equation: a review of its capabilities in pharmacological modelling

(2008) Sylvain Goutelle et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY