FTO mediates LINE1 m 6 A demethylation and chromatin regulation in mESCs and mouse development
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
FTO mediates LINE1 m
6
A demethylation and chromatin regulation in mESCs and mouse development
Authors
Keywords
-
Journal
SCIENCE
Volume 376, Issue 6596, Pages 968-973
Publisher
American Association for the Advancement of Science (AAAS)
Online
2022-05-06
DOI
10.1126/science.abe9582
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
- (2021) Ying Qing et al. MOLECULAR CELL
- m6A RNA methylation regulates the fate of endogenous retroviruses
- (2021) Tomasz Chelmicki et al. NATURE
- METTL3 regulates heterochromatin in mouse embryonic stem cells
- (2021) Wenqi Xu et al. NATURE
- The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
- (2021) Jiadong Liu et al. NATURE
- L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force
- (2021) Sung-Yeon Hwang et al. Nature Communications
- Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
- (2021) Yi Liu et al. Cell Metabolism
- FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell
- (2021) Sébastien Relier et al. Nature Communications
- Chromatin and transcriptional regulation by reversible RNA methylation
- (2021) Jiangbo Wei et al. CURRENT OPINION IN CELL BIOLOGY
- METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
- (2020) Hao Chen et al. CELL RESEARCH
- N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
- (2020) Jun Liu et al. SCIENCE
- Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation
- (2020) J. Yuyang Lu et al. Cell Reports
- Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
- (2020) Rui Su et al. CANCER CELL
- The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues
- (2020) Radha Raman Pandey et al. Cell Reports
- FTO controls reversible m6Am RNA methylation during snRNA biogenesis
- (2019) Jan Mauer et al. Nature Chemical Biology
- Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
- (2019) Yue Huang et al. CANCER CELL
- An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
- (2019) Soo-Mi Kweon et al. MOLECULAR CELL
- Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
- (2019) Hailing Shi et al. MOLECULAR CELL
- High-resolution, strand-specific R-loop mapping via S9.6-based DNA–RNA immunoprecipitation and high-throughput sequencing
- (2019) Lionel A. Sanz et al. Nature Protocols
- Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome
- (2019) Konstantinos Boulias et al. MOLECULAR CELL
- PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
- (2019) Erdem Sendinc et al. MOLECULAR CELL
- m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
- (2019) Seungwon Yang et al. Nature Communications
- Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues
- (2019) Jun’e Liu et al. MOLECULAR CELL
- A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity
- (2018) Michelle Percharde et al. CELL
- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
- (2018) Kenjiro Adachi et al. Cell Stem Cell
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells
- (2018) Diana Guallar et al. NATURE GENETICS
- N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
- (2018) Yang Wang et al. NATURE NEUROSCIENCE
- Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
- (2018) Jiangbo Wei et al. MOLECULAR CELL
- Molecular characteristics of early-stage female germ cells revealed by RNA sequencing of low-input cells and analysis of genome-wide DNA methylation
- (2018) Binbin Ma et al. DNA RESEARCH
- Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
- (2018) Shinichiro Akichika et al. SCIENCE
- Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis
- (2017) Liping Li et al. HUMAN MOLECULAR GENETICS
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo
- (2017) Joanna W Jachowicz et al. NATURE GENETICS
- The landscape of accessible chromatin in mammalian preimplantation embryos
- (2016) Jingyi Wu et al. NATURE
- Reversible methylation of m6Am in the 5′ cap controls mRNA stability
- (2016) Jan Mauer et al. NATURE
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- HISAT: a fast spliced aligner with low memory requirements
- (2015) Daehwan Kim et al. NATURE METHODS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Transcription factor trapping by RNA in gene regulatory elements
- (2015) A. A. Sigova et al. SCIENCE
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
- (2014) Pedro J. Batista et al. Cell Stem Cell
- A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice
- (2014) Safia Malki et al. DEVELOPMENTAL CELL
- “One code to find them all”: a perl tool to conveniently parse RepeatMasker output files
- (2014) Marc Bailly-Bechet et al. Mobile DNA
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates
- (2013) Li Shen et al. PLoS One
- The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
- (2012) Stefanie Seisenberger et al. MOLECULAR CELL
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- KAP1 controls endogenous retroviruses in embryonic stem cells
- (2010) Helen M. Rowe et al. NATURE
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice
- (2010) Xue Gao et al. PLoS One
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Inactivation of the Fto gene protects from obesity
- (2009) Julia Fischer et al. NATURE
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More