Ionizing radiation technology to improve the physicochemical and biological properties of natural compounds by molecular modification: A review

A novel radiolytic rotenone derivative, rotenoisin A, displays potent anticarcinogenic activity in breast cancer cells

(2021) Dong-ho Bak et al.   JOURNAL OF RADIATION RESEARCH

Chrysin Derivative CM1 and Exhibited Anti-Inflammatory Action by Upregulating Toll-Interacting Protein Expression in Lipopolysaccharide-Stimulated RAW264.7 Macrophage Cells

(2021) Eui-Baek Byun et al.   MOLECULES

HMOC, a chrysin derivative, induces tolerogenic properties in lipopolysaccharide-stimulated dendritic cells

(2021) Ha-Yeon Song et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

(2021) Raife Dilek Turan et al.   Scientific Reports

Polyphenols from Food and Natural Products: Neuroprotection and Safety

(2020) Rui F. M. Silva et al.   Antioxidants

Improvement of 6-gingerol production in ginger rhizomes (Zingiber officinale Roscoe) plants by mutation breeding using gamma irradiation

(2020) Asmaa M. Magdy et al.   APPLIED RADIATION AND ISOTOPES

Gamma‑irradiation degraded sulfated polysaccharide from a new red algal strain Pyropia yezoensis Sookwawon 104 with in vitro antiproliferative activity

(2020) Dan He et al.   Oncology Letters

Effect of γ-irradiation on the structure and antioxidant activity of polysaccharide isolated from the fruiting bodies of Morchella sextelata

(2020) Chuan Xiong et al.   BIOSCIENCE REPORTS

Comparisons of Functional Properties of Polysaccharides from Nostoc flagelliforme under Three Culture Conditions

(2019) Shi-gang Shen et al.   Polymers

Nutraceutical Potential of Seaweed Polysaccharides: Structure, Bioactivity, Safety, and Toxicity

(2019) Bhakti Tanna et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

A novel chrysin derivative produced by gamma irradiation attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in Balb/c mice

(2019) Ha-Yeon Song et al.   FOOD AND CHEMICAL TOXICOLOGY

Tumor Microenvironment as A “Game Changer” in Cancer Radiotherapy

(2019) Magdalena Jarosz-Biej et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gamma-Irradiated Chrysin Improves Anticancer Activity in HT-29 Colon Cancer Cells Through Mitochondria-Related Pathway

(2019) Ha-Yeon Song et al.   JOURNAL OF MEDICINAL FOOD

Radiation-Induced Transformations of C6H6 Molecules in Solid Noble-Gas Matrices: Is Benzene Intrinsically Resistant in Condensed Media?

(2019) Mariia A. Lukianova et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Gamma-Irradiation-Prepared Low Molecular Weight Hyaluronic Acid Promotes Skin Wound Healing

(2019) Huang et al.   Polymers

GLM, a novel luteolin derivative, attenuates inflammatory responses in dendritic cells: Therapeutic potential against ulcerative colitis

(2019) Woo Sik Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A hydroxyethyl derivative of chrysin exhibits anti-inflammatory activity in dendritic cells and protective effects against dextran sodium salt-induced colitis in mice

(2019) Ha-Yeon Song et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Gamma-irradiated black ginseng extract inhibits mast cell degranulation and suppresses atopic dermatitis-like skin lesions in mice

(2018) Jung Ae Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Gamma irradiation-assisted degradation of rosmarinic acid and evaluation of structures and anti-adipogenic properties

(2018) Gyeong Han Jeong et al.   FOOD CHEMISTRY

Enhanced nutraceutical potential of gamma irradiated black soybean extracts

(2018) Veda Krishnan et al.   FOOD CHEMISTRY

Effect of gamma irradiation on the anti-oxidant and anti-melanogenic activity of black ginseng extract in B16F10 melanoma cells

(2018) Ha-Yeon Song et al.   RADIATION PHYSICS AND CHEMISTRY

Ionizing radiation processing and its potential in advancing biorefining and nanocellulose composite materials manufacturing

(2018) Michael T. Postek et al.   RADIATION PHYSICS AND CHEMISTRY

Effect of gamma irradiation on the extraction yield, antioxidant, and antityrosinase activities of pistachio green hull extract

(2018) Ali Abolhasani et al.   RADIATION PHYSICS AND CHEMISTRY

Effect of gamma irradiation on structure, physicochemical and immunomodulatory properties of Astragalus polysaccharides

(2018) Lina Ren et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

γ-Irradiation of oat grain – Effect on physico-chemical, structural, thermal, and antioxidant properties of extracted starch

(2017) Rumaisa Mukhtar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gamma-Irradiated Luteolin Inhibits 3-Isobutyl-1-Methylxanthine-Induced Melanogenesis Through the Regulation of CREB/MITF, PI3K/Akt, and ERK Pathways in B16BL6 Melanoma Cells

(2017) Eui-Baek Byun et al.   JOURNAL OF MEDICINAL FOOD

Enhanced biological activities of gamma-irradiated persimmon leaf extract

(2017) Byoung-Ok Cho et al.   JOURNAL OF RADIATION RESEARCH

Gamma-irradiated β-glucan modulates signaling molecular targets of hepatocellular carcinoma in rats

(2017) Sawsan M Elsonbaty et al.   TUMOR BIOLOGY

The modification of natural products for medical use

(2017) Zongru Guo   Acta Pharmaceutica Sinica B

Characterization of low molecular weight fragments from gamma irradiated κ-carrageenan used as plant growth promoter

(2016) Lucille V. Abad et al.   RADIATION PHYSICS AND CHEMISTRY

Effect of gamma irradiation on the change of solubility and anti-inflammation activity of chrysin in macrophage cells and LPS-injected endotoxemic mice

(2016) Eui-Baek Byun et al.   RADIATION PHYSICS AND CHEMISTRY

The early history of food irradiation

(2016) Dieter A.E. Ehlermann   RADIATION PHYSICS AND CHEMISTRY

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages

(2015) Eui-Baek Byun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Novel Radiolytic Rotenone Derivative, Rotenoisin B with Potent Anti-Carcinogenic Activity in Hepatic Cancer Cells

(2015) Srilatha Badaboina et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gamma-irradiatedβ-glucan induces immunomodulation and anticancer activity through MAPK and NF-κB pathways

(2015) Eui-Baek Byun et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Design, synthesis and exploring the quantitative structure–activity relationship of some antioxidant flavonoid analogues

(2014) Sreeparna Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Gamma irradiation induced modification of bean polysaccharides: Impact on physicochemical, morphological and antioxidant properties

(2014) Peerzada R. Hussain et al.   CARBOHYDRATE POLYMERS

Bioactive fungal polysaccharides as potential functional ingredients in food and nutraceuticals

(2014) Ioannis Giavasis   CURRENT OPINION IN BIOTECHNOLOGY

Protein Modification During Ingredient Preparation and Food Processing: Approaches to Improve Food Processability and Nutrition

(2014) Dongxiao Sun-Waterhouse et al.   Food and Bioprocess Technology

Anti-inflammatory effect of gamma-irradiated genistein through inhibition of NF-κB and MAPK signaling pathway in lipopolysaccharide-induced macrophages

(2014) Eui-Baek Byun et al.   FOOD AND CHEMICAL TOXICOLOGY

Degradation of cyanidin-3-rutinoside and formation of protocatechuic acid methyl ester in methanol solution by gamma irradiation

(2014) Seung Sik Lee et al.   FOOD CHEMISTRY

Antioxidant Capacities and Total Phenolic Contents Enhancement with Acute Gamma Irradiation in Curcuma alismatifolia (Zingiberaceae) Leaves

(2014) Sima Taheri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Gamma-Irradiated Influenza A Virus Provides Adjuvant Activity to a Co-Administered Poorly Immunogenic SFV Vaccine in Mice

(2014) Rachelle Babb et al.   Frontiers in Immunology

Preparation of low molecular weight fucoidan by gamma-irradiation and its anticancer activity

(2013) Jong-il Choi et al.   CARBOHYDRATE POLYMERS

Status of Bioactive Compounds in Foods, with Focus on Fruits and Vegetables

(2013) M. N. Shashirekha et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Radiolytic transformation of rotenone with potential anti-adipogenic activity

(2012) Chul-Hong Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High-dose green tea polyphenols induce nephrotoxicity in dextran sulfate sodium-induced colitis mice by down-regulation of antioxidant enzymes and heat-shock protein expressions

(2011) Hirofumi Inoue et al.   CELL STRESS & CHAPERONES

ENHANCED BIOLOGICAL ACTIVITIES OF LAMINARIN DEGRADED BY GAMMA-RAY IRRADIATION

(2011) JONG-IL CHOI et al.   JOURNAL OF FOOD BIOCHEMISTRY

Effect of gamma irradiation on the conversion of ginsenoside Rb1 to Rg3

(2011) Jae-Hun Kim et al.   RADIATION PHYSICS AND CHEMISTRY

Hepatotoxicity of high oral dose (−)-epigallocatechin-3-gallate in mice

(2009) Joshua D. Lambert et al.   FOOD AND CHEMICAL TOXICOLOGY

Antioxidant properties of Maillard reaction products obtained by gamma-irradiation of whey proteins

(2009) S.P. Chawla et al.   FOOD CHEMISTRY

γ-Irradiation Improves the Color and Antioxidant Properties of Chaga Mushroom (Inonotus obliquus) Extract

(2009) Jae-Hun Kim et al.   JOURNAL OF MEDICINAL FOOD

Radiolysis study of genistein in methanolic solution

(2009) Hee Jin Jung et al.   RADIATION PHYSICS AND CHEMISTRY

Immune-enhancing activities of low molecular weight β-glucan depolymerized by gamma irradiation

(2009) Nak-Yun Sung et al.   RADIATION PHYSICS AND CHEMISTRY

Wastewater treatment using gamma irradiation: Tétouan pilot station, Morocco

(2009) Loubna Tahri et al.   RADIATION PHYSICS AND CHEMISTRY

Effects of gamma irradiation on the physical and structural properties of β-glucan

(2007) Eui-Hong Byun et al.   RADIATION PHYSICS AND CHEMISTRY