Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA

The Srs2 helicase dampens DNA damage checkpoint by recycling RPA from chromatin

(2021) Nalini Dhingra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Maintenance by DNA Helicase B

(2020) Lindsey Hazeslip et al.   Genes

Bulk and single-molecule analysis of a bacterial DNA2-like helicase–nuclease reveals a single-stranded DNA looping motor

(2020) Oliver J Wilkinson et al.   NUCLEIC ACIDS RESEARCH

Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair

(2020) Colleen C. Caldwell et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

DNA stretching induces Cas9 off-target activity

(2019) Matthew D. Newton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamics and selective remodeling of the DNA-binding domains of RPA

(2019) Nilisha Pokhrel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RPA Phosphorylation Inhibits DNA Resection

(2019) Michael M. Soniat et al.   MOLECULAR CELL

Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase

(2019) Michael R. Wasserman et al.   CELL

Dynamics of DNA nicking and unwinding by the RepC–PcrA complex

(2019) Carolina Carrasco et al.   NUCLEIC ACIDS RESEARCH

Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Fragile X Mental Retardation Gene

(2018) Gulfem D. Guler et al.   Frontiers in Molecular Neuroscience

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA

(2018) Luke A. Yates et al.   Nature Communications

Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism

(2017) Sanket Awate et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

(2017) Nilisha Pokhrel et al.   NUCLEIC ACIDS RESEARCH

Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation

(2017) Luisina De Tullio et al.   Cell Reports

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

HELB Is a Feedback Inhibitor of DNA End Resection

(2016) Ján Tkáč et al.   MOLECULAR CELL

Chemo-mechanical pushing of proteins along single-stranded DNA

(2016) Joshua E. Sokoloski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicase Processivity and Not the Unwinding Velocity Exhibits Universal Increase with Force

(2015) David L. Pincus et al.   BIOPHYSICAL JOURNAL

Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin

(2015) Jeannine Gerhardt et al.   EXPERIMENTAL CELL RESEARCH

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

(2015) Felix R Day et al.   NATURE GENETICS

Characteristics and concepts of dynamic hub proteins in DNA processing machinery from studies of RPA

(2015) Norie Sugitani et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

An Overview of the Molecular Mechanisms of Recombinational DNA Repair

(2015) Stephen C. Kowalczykowski   Cold Spring Harbor Perspectives in Biology

Human DNA Helicase B Functions in Cellular Homologous Recombination and Stimulates Rad51-Mediated 5′-3′ Heteroduplex Extension In Vitro

(2015) Hanjian Liu et al.   PLoS One

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

(2014) Alexandre Maréchal et al.   CELL RESEARCH

A toolbox for generating single-stranded DNA in optical tweezers experiments

(2013) Andrea Candelli et al.   BIOPOLYMERS

Elastic properties and secondary structure formation of single-stranded DNA at monovalent and divalent salt conditions

(2013) Alessandro Bosco et al.   NUCLEIC ACIDS RESEARCH

On the mechanism of recombination hotspot scanning during double-stranded DNA break resection

(2013) C. Carrasco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Human DNA Helicase B (HDHB) Binds to Replication Protein A and Facilitates Cellular Recovery from Replication Stress

(2011) Gulfem Dilek Guler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combining optical trapping, fluorescence microscopy and micro-fluidics for single molecule studies of DNA–protein interactions

(2011) Andrea Candelli et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Inching over hurdles: How DNA helicases move on crowded lattices

(2010) Maria Spies et al.   CELL CYCLE

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Efficient preparation of internally modified single-molecule constructs using nicking enzymes

(2010) N. Luzzietti et al.   NUCLEIC ACIDS RESEARCH

Visualizing helicases unwinding DNA at the single molecule level

(2010) Natali Fili et al.   NUCLEIC ACIDS RESEARCH

The AddAB helicase–nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain

(2010) Joseph T.P. Yeeles et al.   NUCLEIC ACIDS RESEARCH

Mechanistic Basis of 5′-3′ Translocation in SF1B Helicases

(2009) Kayarat Saikrishnan et al.   CELL

Single-Molecule Analysis Reveals Differential Effect of ssDNA-Binding Proteins on DNA Translocation by XPD Helicase

(2009) Masayoshi Honda et al.   MOLECULAR CELL

DNA binding to RecD: role of the 1B domain in SF1B helicase activity

(2008) Kayarat Saikrishnan et al.   EMBO JOURNAL

Ferroplasma acidarmanus RPA2 Facilitates Efficient Unwinding of Forked DNA Substrates by Monomers of FacXPD Helicase

(2008) Robert A. Pugh et al.   JOURNAL OF MOLECULAR BIOLOGY