Imaging the distribution of skin lipids and topically applied compounds in human skin using mass spectrometry

MALDI imaging facilitates new topical drug development process by determining quantitative skin distribution profiles

(2018) David Bonnel et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Inter-laboratory skin distribution study of 4- n -butyl resorcinol: The importance of liquid chromatography/mass spectrometry (HPLC–MS/MS) bioanalytical validation

(2017) William Wargniez et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Skin Penetration Enhancement by Natural Oils for Dihydroquercetin Delivery

(2017) Vytis Čižinauskas et al.   MOLECULES

MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) of skin: Aspects of sample preparation

(2017) Cristiana Santos de Macedo et al.   TALANTA

Fatty acids penetration into human skin ex vivo: A TOF-SIMS analysis approach

(2017) Vytis Čižinauskas et al.   Biointerphases

The chemistry, function and (patho)physiology of stratum corneum barrier ceramides

(2017) D. J. Moore et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Age-Related Changes to Human Stratum Corneum Lipids Detected Using Time-of-Flight Secondary Ion Mass Spectrometry Following in Vivo Sampling

(2016) Nichola J. Starr et al.   ANALYTICAL CHEMISTRY

Free fatty acids chain length distribution affects the permeability of skin lipid model membranes

(2016) Masayuki Uchiyama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry (TOF-SIMS)

(2015) Peter Sjövall et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Quantitative 3D molecular cutaneous absorption in human skin using label free nonlinear microscopy

(2015) Xueqin Chen et al.   JOURNAL OF CONTROLLED RELEASE

Lipid changes within the epidermis of living skin equivalents observed across a time-course by MALDI-MS imaging and profiling

(2015) Christopher A. Mitchell et al.   Lipids in Health and Disease

Imaging of Distribution of Topically Applied Drug Molecules in Mouse Skin by Combination of Time-of-Flight Secondary Ion Mass Spectrometry and Scanning Electron Microscopy

(2014) Peter Sjövall et al.   ANALYTICAL CHEMISTRY

Role of lipids in the formation and maintenance of the cutaneous permeability barrier

(2013) Kenneth R. Feingold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis

(2013) Peter M. Elias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The important role of stratum corneum lipids for the cutaneous barrier function

(2013) J. van Smeden et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Studying the penetration of fatty acids into human skin by ex vivo TOF-SIMS imaging

(2013) Toma Kezutyte et al.   Biointerphases

Controlled penetration of ceramides into and across the stratum corneum using various types of microemulsions and formulation associated toxicity studies

(2013) Fitsum F. Sahle et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cluster TOF-SIMS imaging as a tool for micrometric histology of lipids in tissue

(2013) Claudia Bich et al.   MASS SPECTROMETRY REVIEWS

Distribution and Visualisation of Chlorhexidine Within the Skin Using ToF-SIMS: A Potential Platform for the Design of More Efficacious Skin Antiseptic Formulations

(2013) Amy M. Judd et al.   PHARMACEUTICAL RESEARCH

Lipidomic and Spatio-Temporal Imaging of Fat by Mass Spectrometry in Mice Duodenum during Lipid Digestion

(2013) Alexandre Seyer et al.   PLoS One

The stratum corneum comprises three layers with distinct metal-ion barrier properties

(2013) Akiharu Kubo et al.   Scientific Reports

MALDI imaging in human skin tissue sections: focus on various matrices and enzymes

(2012) Bernd Enthaler et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

(2012) Ichiro Iwai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Imaging the Distribution of Sodium Dodecyl Sulfate in Skin by Confocal Raman and Infrared Microspectroscopy

(2012) G. Mao et al.   PHARMACEUTICAL RESEARCH

Imaging Mass Spectrometry Visualizes Ceramides and the Pathogenesis of Dorfman-Chanarin Syndrome Due to Ceramide Metabolic Abnormality in the Skin

(2012) Naoko Goto-Inoue et al.   PLoS One

MALDI-MS imaging of lipids in ex vivo human skin

(2011) Philippa J. Hart et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improved sample preparation for MALDI–MSI of endogenous compounds in skin tissue sections and mapping of exogenous active compounds subsequent to ex-vivo skin penetration

(2011) Bernd Enthaler et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS)

(2011) Melissa K. Passarelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

(2011) Jeroen van Smeden et al.   JOURNAL OF LIPID RESEARCH

Investigation of the Molecular Structure of the Human Stratum Corneum Ceramides [NP] and [EOS] by Mass Spectrometry

(2011) A. Hinder et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Synthesis of fluorescent C24-ceramide: Evidence for acyl chain length dependent differences in penetration of exogenous NBD-ceramides into human skin

(2009) Jakub Novotný et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thematic review series: Skin Lipids.Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism

(2008) Peter M. Elias et al.   JOURNAL OF LIPID RESEARCH

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

(2008) Christian W. Freudiger et al.   SCIENCE