Neutrophil and natural killer cell imbalances prevent muscle stem cell–mediated regeneration following murine volumetric muscle loss

TGFβ signalling acts as a molecular brake of myoblast fusion

(2021) Julie Melendez et al.   Nature Communications

TGFβ signaling curbs cell fusion and muscle regeneration

(2021) Francesco Girardi et al.   Nature Communications

The Role of Innate and Adaptive Immune Cells in Skeletal Muscle Regeneration

(2021) Natalia Ziemkiewicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Evolving Roles of Muscle-Resident Fibro-Adipogenic Progenitors in Health, Regeneration, Neuromuscular Disorders, and Aging

(2021) Marine Theret et al.   Frontiers in Physiology

Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging

(2021) Jacqueline A Larouche et al.   eLife

Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils

(2021) Bo Ri Seo et al.   Science Translational Medicine

Divergent Roles of Inflammation in Skeletal Muscle Recovery From Injury

(2020) Emily E. Howard et al.   Frontiers in Physiology

Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis

(2020) David M. Stepien et al.   JOURNAL OF IMMUNOLOGY

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells

(2020) James F. Markworth et al.   JCI Insight

Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss

(2020) Suradip Das et al.   Communications Biology

Determination of a Critical Size Threshold for Volumetric Muscle Loss in the Mouse Quadriceps

(2019) Shannon Emily Anderson et al.   TISSUE ENGINEERING PART C-METHODS

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations

(2019) Lorenzo Giordani et al.   MOLECULAR CELL

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases

(2019) Junio Dort et al.   Stem Cells International

Therapeutic Approaches for Volumetric Muscle Loss Injury: A Systematic Review and Meta-Analysis

(2019) Sarah M. Greising et al.   TISSUE ENGINEERING PART B-REVIEWS

Interleukin-36γ–producing macrophages drive IL-17–mediated fibrosis

(2019) Sven D. Sommerfeld et al.   Science Immunology

NicheNet: modeling intercellular communication by linking ligands to target genes

(2019) Robin Browaeys et al.   NATURE METHODS

Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury

(2019) Benjamin T. Corona et al.   TISSUE ENGINEERING PART A

Cell Fusion: Merging Membranes and Making Muscle

(2019) Michael J. Petrany et al.   TRENDS IN CELL BIOLOGY

Early rehabilitation for volumetric muscle loss injury augments endogenous regenerative aspects of muscle strength and oxidative capacity

(2018) Sarah M. Greising et al.   BMC MUSCULOSKELETAL DISORDERS

Neutrophils in tissue injury and repair

(2018) Jing Wang   CELL AND TISSUE RESEARCH

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

(2018) Michael N. Wosczyna et al.   DEVELOPMENTAL CELL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Tregcells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration

(2018) Marisella Panduro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration

(2018) Jacqueline Larouche et al.   Cell Death & Disease

The Role of T Lymphocytes in Skeletal Muscle Repair From Traumatic and Contraction-Induced Injury

(2018) Michael R. Deyhle et al.   Frontiers in Physiology

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Tissue-Specific Roles of NKT Cells in Tumor Immunity

(2018) Masaki Terabe et al.   Frontiers in Immunology

MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool

(2018) Alicia Mayeuf-Louchart et al.   Skeletal Muscle

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

(2018) Marcus Ruscetti et al.   SCIENCE

CCAAT/Enhancer Binding Protein β inhibits myogenic differentiation via ID3

(2018) Hamood AlSudais et al.   Scientific Reports

A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System

(2017) Alon Oyler-Yaniv et al.   IMMUNITY

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration

(2016) Micah T. Webster et al.   Cell Stem Cell

Influence of exercise and aging on extracellular matrix composition in the skeletal muscle stem cell niche

(2016) Koyal Garg et al.   JOURNAL OF APPLIED PHYSIOLOGY

Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype

(2016) Joana Capote et al.   JOURNAL OF CELL BIOLOGY

Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength

(2016) Serge Summermatter et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

(2016) Michelle Rozo et al.   NATURE MEDICINE

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

(2016) Laura Lukjanenko et al.   NATURE MEDICINE

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

(2016) K. Sadtler et al.   SCIENCE

Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development

(2016) Matthew Timothy Tierney et al.   Cell Reports

Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

(2016) Carlos A. Aguilar et al.   Stem Cell Reports

Volumetric Muscle Loss

(2016) Brian F. Grogan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Biomimetic scaffolds for regeneration of volumetric muscle loss in skeletal muscle injuries

(2015) Jonathan M. Grasman et al.   Acta Biomaterialia

Natural Killer Cells Limit Cardiac Inflammation and Fibrosis by Halting Eosinophil Infiltration

(2015) SuFey Ong et al.   AMERICAN JOURNAL OF PATHOLOGY

Creatine kinase B is necessary to limit myoblast fusion during myogenesis

(2015) Adriana Simionescu-Bankston et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanical Tension Drives Cell Membrane Fusion

(2015) Ji Hoon Kim et al.   DEVELOPMENTAL CELL

IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ

(2015) Yin Guo et al.   JOURNAL OF IMMUNOLOGY

Volumetric muscle loss leads to permanent disability following extremity trauma

(2015) Benjamin T. Corona et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Therapeutic strategies for preventing skeletal muscle fibrosis after injury

(2015) Koyal Garg et al.   Frontiers in Pharmacology

Upregulated IL-1β in dysferlin-deficient muscle attenuates regeneration by blunting the response to pro-inflammatory macrophages

(2015) Tatiana V. Cohen et al.   Skeletal Muscle

Expression of CCAAT/Enhancer Binding Protein Beta in Muscle Satellite Cells Inhibits Myogenesis in Cancer Cachexia

(2015) François Marchildon et al.   PLoS One

Losartan administration reduces fibrosis but hinders functional recovery after volumetric muscle loss injury

(2014) Koyal Garg et al.   JOURNAL OF APPLIED PHYSIOLOGY

Volumetric muscle loss: Persistent functional deficits beyond frank loss of tissue

(2014) Koyal Garg et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss

(2014) B. M. Sicari et al.   Science Translational Medicine

Isolation, Culture, and Transplantation of Muscle Satellite Cells

(2014) Norio Motohashi et al.   Jove-Journal of Visualized Experiments

Cellular Mechanisms of Tissue Fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis

(2013) Richard L. Lieber et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion

(2013) C. Florian Bentzinger et al.   Cell Stem Cell

Macrophage activation and skeletal muscle healing following traumatic injury

(2013) Margaret L Novak et al.   JOURNAL OF PATHOLOGY

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Human NK Cells Induce Neutrophil Apoptosis via an NKp46- and Fas-Dependent Mechanism

(2012) F. B. Thoren et al.   JOURNAL OF IMMUNOLOGY

Molecular definition of the identity and activation of natural killer cells

(2012) Natalie A Bezman et al.   NATURE IMMUNOLOGY

The defensive alliance between neutrophils and NK cells as a novel arm of innate immunity

(2010) Claudio Costantini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage Migration Inhibitory Factor in Normal Human Skeletal Muscle and Inflammatory Myopathies

(2010) Jens Reimann et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Role of matrix metalloproteinases in skeletal muscle

(2010) Xiaoping Chen et al.   Cell Adhesion & Migration

Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β

(2009) Sylvia A. Vetrone et al.   JOURNAL OF CLINICAL INVESTIGATION

Fibrinogen drives dystrophic muscle fibrosis via a TGF /alternative macrophage activation pathway

(2008) B. Vidal et al.   GENES & DEVELOPMENT

Secreted Protein Acidic and Rich in Cysteine (SPARC) in Human Skeletal Muscle

(2008) Louise H. Jørgensen et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY