Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron

Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529

(2022) Tongqing Zhou et al.   SCIENCE

Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

(2021) Zhuoming Liu et al.   Cell Host & Microbe

Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

(2021) Gabriele Cerutti et al.   Cell Host & Microbe

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

(2021) Pengfei Wang et al.   NATURE

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

(2021) Zijun Wang et al.   NATURE

Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody

(2021) Bharat Madan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients

(2021) Ahmed S. Fahad et al.   Frontiers in Immunology

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

(2021) Matthew McCallum et al.   CELL

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

(2021) Shabir A. Madhi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

(2021) Bryan E. Jones et al.   Science Translational Medicine

In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

(2021) Dapeng Li et al.   CELL

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

(2021) Delphine Planas et al.   NATURE

Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

(2021) Jianliang Xu et al.   NATURE

mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates

(2021) Kizzmekia S. Corbett et al.   NATURE IMMUNOLOGY

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

(2021) Lingshu Wang et al.   SCIENCE

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

(2021) Amarendra Pegu et al.   SCIENCE

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

(2021) Kizzmekia S. Corbett et al.   SCIENCE

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

(2021) Joseph R. Francica et al.   Science Translational Medicine

Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

(2021) Gabriele Cerutti et al.   Cell Reports

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

(2021) Bailey B. Banach et al.   Cell Reports

Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera

(2021) Takuya Tada et al.   iScience

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

(2020) Xiaolong Tian et al.   Emerging Microbes & Infections

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

(2020) Yan Wu et al.   SCIENCE

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

(2020) Meng Yuan et al.   SCIENCE

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

(2020) Lihong Liu et al.   NATURE

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

(2020) Lakshmanane Premkumar et al.   Science Immunology

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

(2020) Luca Piccoli et al.   CELL

Spike mutation D614G alters SARS-CoV-2 fitness

(2020) Jessica A. Plante et al.   NATURE

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

(2020) Alina Baum et al.   SCIENCE

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

(2020) Tongqing Zhou et al.   Cell Reports

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

(2020) Lizhou Zhang et al.   Nature Communications

Ultrasonically-guided flow focusing generates precise emulsion droplets for high-throughput single cell analyses

(2019) Colton E. Lagerman et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

(2018) Bo Wang et al.   NATURE BIOTECHNOLOGY

Optimization of Soluble Expression and Purification of Recombinant Human Rhinovirus Type-14 3C Protease Using Statistically Designed Experiments: Isolation and Characterization of the Enzyme

(2017) Georgia Antoniou et al.   MOLECULAR BIOTECHNOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

(2011) X. Wu et al.   SCIENCE

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE