Synthesis of some 5,6-diaryl-1,2,4-triazine derivatives and investigation of their cyclooxygenase (COX) inhibitory activity

Pharmacologic activities of 5, 6-Diaryl/heteroaryl-3-substituted-1, 2, 4-triazines as a privileged scaffold in drug development

(2021) Zahra Zakeri Khatir et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Effect of o-difluoro and p-methyl substituents on the structure, optical properties and anti-inflammatory activity of phenoxy thiazole acetamide derivatives: Theoretical and experimental studies

(2019) Hussien Ahmed Khamees et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, biological evaluation, and docking studies of novel 5,6-diaryl-1,2,4-triazine thiazole derivatives as a new class of α -glucosidase inhibitors

(2018) Guangcheng Wang et al.   BIOORGANIC CHEMISTRY

Synthesis, cyclooxygenase-2 inhibition, anti-inflammatory evaluation and docking study of substituted-N-(3,4,5-trimethoxyphenyl)-benzo[d]oxazole derivatives

(2018) Avneet Kaur et al.   Medicinal Chemistry

Design, synthesis, evaluation and molecular modelling studies of some novel 5,6-diphenyl-1,2,4-triazin-3(2H)-ones bearing five-member heterocyclic moieties as potential COX-2 inhibitors: A hybrid pharmacophore approach

(2016) Anupam G. Banerjee et al.   BIOORGANIC CHEMISTRY

Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond

(2016) Praveen Rao et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6–diphenyl–1,2,4–triazin–3(2 H )–one derivatives bearing 5–substituted 1,3,4–oxadiazole as potential anti–inflammatory and analgesic agents

(2015) Anupam G. Banerjee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo

(2015) Ghewa A. El-Achkar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis, cyclooxygenase inhibitory effects, and molecular modeling study of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and -2-alkylsulfonyl-1 H -imidazole derivatives

(2013) Amir Assadieskandar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors

(2013) Hamid Irannejad et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, anti-inflammatory evaluation, and docking studies of some new thiazole derivatives

(2013) Pran Kishore Deb et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents

(2012) I. Apostolidis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of thieno [2′,3′:4,5]pyrimido[1,2-b][1,2,4]triazines and thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidines as anti-inflammatory and analgesic agents

(2012) Hayam M. Ashour et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Solvent-Free Synthesis of Alkylthiazolium-Based Ionic Liquids and their Use as Catalysts in the Intramolecular Stetter Reaction

(2009) Giang Vo-Thanh et al.   SYNLETT

Synthesis, structure elucidation and identification of antitumoural properties of novel fused 1,2,4-triazine aryl derivatives

(2007) Krzysztof Sztanke et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY