Exogenous Aβ1-42 monomers improve synaptic and cognitive function in Alzheimer's disease model mice

Insight γ-Secretase: Structure, Function and Role in Alzheimer’s Disease

(2021) Suvadeep Mal et al.   CURRENT DRUG TARGETS

Calcium Dyshomeostasis in Alzheimer’s Disease Pathogenesis

(2021) Roberta Cascella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Theta Oscillations in Human Memory

(2020) Nora A. Herweg et al.   TRENDS IN COGNITIVE SCIENCES

Cross-Frequency Phase-Amplitude Coupling between Hippocampal Theta and Gamma Oscillations during Recall Destabilizes Memory and Renders It Susceptible to Reconsolidation Disruption

(2020) Andressa Radiske et al.   JOURNAL OF NEUROSCIENCE

Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells

(2020) Jia-Mou Ren et al.   Molecular Medicine Reports

A DNA-Based FLIM Reporter for Simultaneous Quantification of Lysosomal pH and Ca2+ during Autophagy Regulation

(2020) Zhonghui Zhang et al.   iScience

Amyloid-β Immunotherapy for Alzheimer's Disease - Is It Now A Long Shot…?

(2019) Francesco Panza et al.   ANNALS OF NEUROLOGY

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Molecular Modulation of Human α7 Nicotinic Receptor by Amyloid-β Peptides

(2019) Matías Lasala et al.   Frontiers in Cellular Neuroscience

Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts

(2019) Camila Fabiani et al.   Frontiers in Cellular Neuroscience

Striatal GluN2B involved in motor skill learning and stimulus-response learning

(2018) Yanhong Duan et al.   NEUROPHARMACOLOGY

The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

(2018) Salvatore Incontro et al.   Nature Communications

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

(2018) Eric McDade et al.   NEUROLOGY

Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease

(2018) Kai-Ge Ma et al.   NEUROPEPTIDES

A Physiological Role for Amyloid-β Protein: Enhancement of Learning and Memory

(2017) John E. Morley et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular genetics of early-onset Alzheimer's disease revisited

(2016) Rita Cacace et al.   Alzheimers & Dementia

Spatial Working Memory in Humans Depends on Theta and High Gamma Synchronization in the Prefrontal Cortex

(2016) Ivan Alekseichuk et al.   CURRENT BIOLOGY

Age-dependent inverse correlations in CSF and plasma amyloid-β(1–42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice

(2016) Soo Min Cho et al.   Scientific Reports

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Three-dimensional structure of human γ-secretase

(2014) Peilong Lu et al.   NATURE

Reduction in LFP cross-frequency coupling between theta and gamma rhythms associated with impaired STP and LTP in a rat model of brain ischemia

(2013) Xiaxia Xu et al.   Frontiers in Computational Neuroscience

α7nAchR/NMDAR coupling affects NMDAR function and object recognition

(2013) Shupeng Li et al.   Molecular Brain

The α7nACh–NMDA receptor complex is involved in cue-induced reinstatement of nicotine seeking

(2012) Shupeng Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory

(2012) Daniela Puzzo et al.   NEUROBIOLOGY OF AGING

Role of Key Aromatic Residues in the Ligand-binding Domain of α7 Nicotinic Receptors in the Agonist Action of β-Amyloid

(2011) Mei Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory

(2010) Daniela Puzzo et al.   ANNALS OF NEUROLOGY

Characterization of Age-Dependent and Progressive Cortical Neuronal Degeneration in Presenilin Conditional Mutant Mice

(2010) Mary Wines-Samuelson et al.   PLoS One

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration

(2009) K. Tabuchi et al.   JOURNAL OF NEUROSCIENCE

Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

(2008) Howard Jay Aizenstein et al.   ARCHIVES OF NEUROLOGY